RM35_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RM35_HUMAN
• UniProt AC: Q9NZE8
• Protein Name: 39S ribosomal protein L35, mitochondrial
• Gene Name: MRPL35
• Organism: Homo sapiens (Human).
• Sequence Length: 188
• Subcellular Localization: Mitochondrion .
• Protein Sequence: MAASAFAGAVRAASGILRPLNILASSTYRNCVKNASLISALSTGRFSHIQTPVVSSTPRLTTSERNLTCGHTSVILNRMAPVLPSVLKLPVRSLTYFSARKGKRKTVKAVIDRFLRLHCGLWVRRKAGYKKKLWKKTPARKKRLREFVFCNKTQSKLLDKMTTSFWKRRNWYVDDPYQKYHDRTNLKV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MAASAFAGAVR ----CCHHHHHHHHH	17.87	-
39	Phosphorylation	VKNASLISALSTGRF HHCHHHHHHHHHCCC	28.57	-
56	Phosphorylation	IQTPVVSSTPRLTTS CCCCCCCCCCCCCCC	30.71	-
72	Phosphorylation	RNLTCGHTSVILNRM CCCCCCCHHHHHHCC	15.24	22210691
73	Phosphorylation	NLTCGHTSVILNRMA CCCCCCHHHHHHCCC	11.07	22210691
88	Ubiquitination	PVLPSVLKLPVRSLT CCCHHHHHCCHHHHH	48.89	33845483
106	Phosphorylation	ARKGKRKTVKAVIDR CCCCCCHHHHHHHHH	31.13	-
132	Acetylation	RKAGYKKKLWKKTPA HHCCCHHHHHHCCHH	56.26	158693
152	Ubiquitination	REFVFCNKTQSKLLD HHHHHCCHHHHHHHH	49.47	33845483
152	Acetylation	REFVFCNKTQSKLLD HHHHHCCHHHHHHHH	49.47	27452117
160	Methylation	TQSKLLDKMTTSFWK HHHHHHHHHHHHHHH	37.81	23644510
163	Phosphorylation	KLLDKMTTSFWKRRN HHHHHHHHHHHHHCC	20.59	-
167	2-Hydroxyisobutyrylation	KMTTSFWKRRNWYVD HHHHHHHHHCCCCCC	39.20	-
179	Acetylation	YVDDPYQKYHDRTNL CCCCHHHHCCCCCCC	38.41	21466224
180	Phosphorylation	VDDPYQKYHDRTNLK CCCHHHHCCCCCCCC	8.07	22985185
184	Phosphorylation	YQKYHDRTNLKV--- HHHCCCCCCCCC---	51.46	22985185

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RM35_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RM35_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RM35_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
RM47_HUMAN	MRPL47	physical	28514442
RT30_HUMAN	MRPS30	physical	28514442
RM04_HUMAN	MRPL4	physical	28514442
RM10_HUMAN	MRPL10	physical	28514442
RM28_HUMAN	MRPL28	physical	28514442
RM12_HUMAN	MRPL12	physical	28514442
RM30_HUMAN	MRPL30	physical	28514442
MRS2_HUMAN	MRS2	physical	28514442
RM39_HUMAN	MRPL39	physical	28514442
DCAF1_HUMAN	VPRBP	physical	28514442
RM13_HUMAN	MRPL13	physical	28514442
UBE2O_HUMAN	UBE2O	physical	28514442
RM38_HUMAN	MRPL38	physical	28514442
RM41_HUMAN	MRPL41	physical	28514442
RM40_HUMAN	MRPL40	physical	28514442
RM27_HUMAN	MRPL27	physical	28514442
MASU1_HUMAN	MALSU1	physical	28514442
MAP2_HUMAN	METAP2	physical	28514442
RM15_HUMAN	MRPL15	physical	28514442
RM34_HUMAN	MRPL34	physical	28514442
ROA1_HUMAN	HNRNPA1	physical	28514442
NP1L1_HUMAN	NAP1L1	physical	28514442
IPO5_HUMAN	IPO5	physical	28514442
NP1L4_HUMAN	NAP1L4	physical	28514442
KI67_HUMAN	MKI67	physical	28514442
RT18A_HUMAN	MRPS18A	physical	28514442
RNBP6_HUMAN	RANBP6	physical	28514442
RM48_HUMAN	MRPL48	physical	28514442
RM20_HUMAN	MRPL20	physical	28514442
RM55_HUMAN	MRPL55	physical	28514442
RM49_HUMAN	MRPL49	physical	28514442
RM02_HUMAN	MRPL2	physical	28514442
RM03_HUMAN	MRPL3	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.