| UniProt ID | SNX20_HUMAN | |
|---|---|---|
| UniProt AC | Q7Z614 | |
| Protein Name | Sorting nexin-20 | |
| Gene Name | SNX20 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 316 | |
| Subcellular Localization |
Early endosome membrane Peripheral membrane protein Cytoplasmic side . Cell membrane . Cytoplasm . Nucleus . |
|
| Protein Description | May play a role in cellular vesicle trafficking. Has been proposed to function as a sorting protein that targets SELPLG into endosomes, but has no effect on SELPLG internalization from the cell surface, or on SELPLG-mediated cell-cell adhesion.. | |
| Protein Sequence | MASPEHPGSPGCMGPITQCTARTQQEAPATGPDLPHPGPDGHLDTHSGLSSNSSMTTRELQQYWQNQKCRWKHVKLLFEIASARIEERKVSKFVVYQIIVIQTGSFDNNKAVLERRYSDFAKLQKALLKTFREEIEDVEFPRKHLTGNFAEEMICERRRALQEYLGLLYAIRCVRRSREFLDFLTRPELREAFGCLRAGQYPRALELLLRVLPLQEKLTAHCPAAAVPALCAVLLCHRDLDRPAEAFAAGERALQRLQAREGHRYYAPLLDAMVRLAYALGKDFVTLQERLEESQLRRPTPRGITLKELTVREYLH | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MASPEHPGSP -----CCCCCCCCCC | 29.53 | 23401153 | |
| 9 | Phosphorylation | ASPEHPGSPGCMGPI CCCCCCCCCCCCCCC | 23.67 | 23401153 | |
| 17 | Phosphorylation | PGCMGPITQCTARTQ CCCCCCCCCCCCCCC | 22.26 | 24043423 | |
| 20 | Phosphorylation | MGPITQCTARTQQEA CCCCCCCCCCCCCCC | 14.89 | 24043423 | |
| 89 | Ubiquitination | SARIEERKVSKFVVY HHHHHHHCCCCEEEE | 54.89 | 32015554 | |
| 91 (in isoform 3) | Phosphorylation | - | 24.34 | 27282143 | |
| 91 (in isoform 4) | Phosphorylation | - | 24.34 | - | |
| 105 (in isoform 3) | Phosphorylation | - | 32.58 | 27282143 | |
| 108 (in isoform 3) | Phosphorylation | - | 50.30 | - | |
| 164 | Phosphorylation | RRRALQEYLGLLYAI HHHHHHHHHHHHHHH | 7.97 | 27067055 | |
| 169 | Phosphorylation | QEYLGLLYAIRCVRR HHHHHHHHHHHHHHH | 12.67 | 27067055 | |
| 278 | Phosphorylation | DAMVRLAYALGKDFV HHHHHHHHHHCCCCC | 13.62 | 22210691 | |
| 286 | Phosphorylation | ALGKDFVTLQERLEE HHCCCCCCHHHHHHH | 23.79 | 26329039 | |
| 294 | Phosphorylation | LQERLEESQLRRPTP HHHHHHHHHCCCCCC | 25.74 | 26329039 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SNX20_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SNX20_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SNX20_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| FAM9B_HUMAN | FAM9B | physical | 25416956 | |
| JMJD4_HUMAN | JMJD4 | physical | 28514442 | |
| DIRA1_HUMAN | DIRAS1 | physical | 28514442 | |
| CCHL_HUMAN | HCCS | physical | 28514442 | |
| VP13B_HUMAN | VPS13B | physical | 28514442 | |
| HSP7C_HUMAN | HSPA8 | physical | 28514442 | |
| ENOF1_HUMAN | ENOSF1 | physical | 28514442 | |
| SAHH3_HUMAN | AHCYL2 | physical | 28514442 | |
| HSP74_HUMAN | HSPA4 | physical | 28514442 | |
| PSMD7_HUMAN | PSMD7 | physical | 28514442 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
