VP13B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VP13B_HUMAN
• UniProt AC: Q7Z7G8
• Protein Name: Vacuolar protein sorting-associated protein 13B
• Gene Name: VPS13B
• Organism: Homo sapiens (Human).
• Sequence Length: 4022
• Protein Description: May be involved in protein sorting in post Golgi membrane traffic..
• Protein Sequence: MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSGHIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSIKPRRMQQAAPTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDIVLSVNITSAECYTVGELWDRAFMDISATDLVLRKVINFSDCTVCLDKRNASGKIEFYQDPLLYKCSFRTRLHFTYENLNSKMPSVIKIHTLVESLKLSITDQQLPMFIRIMQLGIALYYGEIGNFKEGEIEDLTCHNKDMLGNITGSEDETRIDMQYPAQHKGQELYSQQDEEQPQGWVSWAWSFVPAIVSYDDGEEDFVGNDPASTMHQQKAQTLKDPIVSIGFYCTKATVTFKLTEMQVESSYYSPQKVKSKEVLCWEQEGTTVEALMMGEPFFDCQIGFVGCRAMCLKGIMGVKDFEENMNRSETEACFFICGDNLSTKGFTYLTNSLFDYRSPENNGTRAEFILDSTHHKETYTEIAGMQRFGAFYMDYLYTMENTSGKGSTNQQDFSSGKSEDLGTVQEKSTKSLVIGPLDFRLDSSAVHRILKMIVCALEHEYEPYSRLKSDIKDENETILNPEEVALLEEYIPTRHTSVTLLKCTCTISMAEFNLLDHLLPVIMGEKNSSNFMNTTNFQSLRPLPSIRILVDKINLEHSVPMYAEQLVHVVSSLTQPSDNLLHYCYVHCYLKIFGFQAGLTSLDCSGSYCLPVPVIPSFSTALYGKLLKLPTCWTKRSQIAITEGIFELPNLTIQATRAQTLLLQAIYQSWSHLGNVSSSAVIEALINEIFLSIGVKSKNPLPTLEGSIQNVELKYCSTSLVKCASGTMGSIKICAKAPVDSGKEKLIPLLQGPSDTKDLHSTKWLNESRKPESLLAPDLMAFTIQVPQYIDYCHNSGAVLLCSIQGLAVNIDPILYTWLIYQPQKRTSRHMQQQPVVAVPLVMPVCRRKEDEVSIGSAPLAKQQSYQASEYASSPVKTKTVTESRPLSVPVKAMLNISESCRSPEERMKEFIGIVWNAVKHLTLQLEVQSCCVFIPNDSLPSPSTIVSGDIPGTVRSWYHGQTSMPGTLVLCLPQIKIISAGHKYMEPLQEIPFVIPRPILEEGDAFPWTISLHNFSIYTLLGKQVTLCLVEPMGCTSTLAVTSQKLLATGPDTRHSFVVCLHVDLESLEIKCSNPQVQLFYELTDIMNKVWNKIQKRGNLNLSPTSPETMAGPVPTSPVRSSIGTAPPDTSTCSPSADIGTTTEGDSIQAGEESPFSDSVTLEQTTSNIGGTSGRVSLWMQWVLPKITIKLFAPDPENKGTEVCMVSELEDLSASIDVQDVYTKVKCKIESFNIDHYRSSLGEECWSLGQCGGVFLSCTDKLNRRTLLVRPISKQDPFSNCSGFFPSTTTKLLDGTHQQHGFLSLTYTKAVTKNVRHKLTSRNERRSFHKLSEGLMDGSPHFLHEILLSAQAFDIVLYFPLLNAIASIFQAKLPKTQKEKRKSPGQPMRTHTLTSRNLPLIYVNTSVIRIFIPKTEEMQPTVEANQAAKEDTVVLKIGSVAMAPQADNPLGRSVLRKDIYQRALNLGILRDPGSEIEDRQYQIDLQSINIGTAQWHQLKPEKESVSGGVVTETERNSQNPALEWNMASSIRRHQERRAILTPVLTDFSVRITGAPAVIFTKVVSPENLHTEEILVCGHSLEVNITTNLDFFLSVAQVQLLHQLIVANMTGLEPSNKAAEISKQEQKKVDIFDGGMAETSSRYSGAQDSGIGSDSVKIRIVQIEQHSGASQHRIARPSRQSSIVKNLNFIPFDIFITASRISLMTYSCMALSKSKSQEQKNNEKTDKSSLNLPEVDSDVAKPNQACISTVTAEDLLRSSISFPSGKKIGVLSLESLHASTRSSARQALGITIVRQPGRRGTGDLQLEPFLYFIVSQPSLLLSCHHRKQRVEVSIFDAVLKGVASDYKCIDPGKTLPEALDYCTVWLQTVPGEIDSKSGIPPSFITLQIKDFLNGPADVNLDISKPLKANLSFTKLDQINLFLKKIKNAHSLAHSEETSAMSNTMVNKDDLPVSKYYRGKLSKPKIHGDGVQKISAQENMWRAVSCFQKISVQTTQIVISMETVPHTSKPCLLASLSNLNGSLSVKATQKVPGIILGSSFLLSINDFLLKTSLKERSRILIGPCCATANLEAKWCKHSGNPGPEQSIPKISIDLRGGLLQVFWGQEHLNCLVLLHELLNGYLNEEGNFEVQVSEPVPQMSSPVEKNQTFKSEQSSDDLRTGLFQYVQDAESLKLPGVYEVLFYNETEDCPGMMLWRYPEPRVLTLVRITPVPFNTTEDPDISTADLGDVLQVPCSLEYWDELQKVFVAFREFNLSESKVCELQLPDINLVNDQKKLVSSDLWRIVLNSSQNGADDQSSASESGSQSTCDPLVTPTALAACTRVDSCFTPWFVPSLCVSFQFAHLEFHLCHHLDQLGTAAPQYLQPFVSDRNMPSELEYMIVSFREPHMYLRQWNNGSVCQEIQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHVVHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSWRSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQIIICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELCVKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSPLFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPSDCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDSPMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEAFQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQKLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATFSICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAIVRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKMLIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTTEWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIVTFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCVEICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKLCITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGKQVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIFTTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRGPGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPESLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGVFTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGRPEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNLLTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEPPPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MLESYVTPILM ----CCHHCHHHHHH	37.22	23663014
5	Phosphorylation	---MLESYVTPILMS ---CCHHCHHHHHHH	10.04	23663014
7	Phosphorylation	-MLESYVTPILMSYV -CCHHCHHHHHHHHH	9.07	23663014
12	Phosphorylation	YVTPILMSYVNRYIK CHHHHHHHHHHHHHH	23.60	23663014
13	Phosphorylation	VTPILMSYVNRYIKN HHHHHHHHHHHHHHH	6.43	23663014
76	Phosphorylation	VPWTKLGSEPVVITI CCCHHCCCCCEEEEE	49.52	-
102	Phosphorylation	GIQDDHESCGSNSTN CCCCCCCCCCCCCCC	21.99	25849741
105	Phosphorylation	DDHESCGSNSTNRST CCCCCCCCCCCCCHH	31.75	25849741
117	Ubiquitination	RSTAESTKSSIKPRR CHHHHHHHHCCCCHH	52.03	-
142	Phosphorylation	LPPGYVQSLIRRVVN CCCHHHHHHHHHHHH	18.73	24719451
157	Ubiquitination	NVNIVINNLILKYVE CHHHEEECHHHHHHC	19.82	22817900
231	Ubiquitination	YQDPLLYKCSFRTRL ECCCCHHHCCCCCEE	24.30	-
233	Phosphorylation	DPLLYKCSFRTRLHF CCCHHHCCCCCEEEE	17.38	30177828
236	Phosphorylation	LYKCSFRTRLHFTYE HHHCCCCCEEEEEHH	35.26	30177828
241	Phosphorylation	FRTRLHFTYENLNSK CCCEEEEEHHCCCCC	21.12	23401153
242	Phosphorylation	RTRLHFTYENLNSKM CCEEEEEHHCCCCCC	11.24	23401153
247	Phosphorylation	FTYENLNSKMPSVIK EEHHCCCCCCCCEEE	33.23	23401153
251	Phosphorylation	NLNSKMPSVIKIHTL CCCCCCCCEEEHHHH	32.73	23401153
312	Phosphorylation	KDMLGNITGSEDETR CHHCCCCCCCCCCCC	38.36	28348404
314	Phosphorylation	MLGNITGSEDETRID HCCCCCCCCCCCCCC	32.97	28348404
318	Phosphorylation	ITGSEDETRIDMQYP CCCCCCCCCCCCCCC	45.29	28348404
321	Ubiquitination	SEDETRIDMQYPAQH CCCCCCCCCCCCCCC	18.16	22817900
395	Ubiquitination	VSIGFYCTKATVTFK EEEEEEECCEEEEEE	16.60	22817900
410	Phosphorylation	LTEMQVESSYYSPQK EEEEEEECCCCCCCC	25.45	28796482
411	Phosphorylation	TEMQVESSYYSPQKV EEEEEECCCCCCCCC	18.00	28796482
412	Phosphorylation	EMQVESSYYSPQKVK EEEEECCCCCCCCCC	19.76	28796482
413	Phosphorylation	MQVESSYYSPQKVKS EEEECCCCCCCCCCC	18.80	28796482
414	Phosphorylation	QVESSYYSPQKVKSK EEECCCCCCCCCCCC	16.78	28796482
430	Ubiquitination	VLCWEQEGTTVEALM EEEEEECCCHHHHHH	26.78	27667366
436	Ubiquitination	EGTTVEALMMGEPFF CCCHHHHHHCCCCCC	1.21	22817900
504	Ubiquitination	SLFDYRSPENNGTRA CCCCCCCCCCCCCCE	39.06	27667366
521	Ubiquitination	ILDSTHHKETYTEIA EEECCCCCCCHHHHH	44.11	-
524	Phosphorylation	STHHKETYTEIAGMQ CCCCCCCHHHHHHHH	11.94	27642862
552	Phosphorylation	ENTSGKGSTNQQDFS CCCCCCCCCCHHHCC	27.89	23312004
553	Phosphorylation	NTSGKGSTNQQDFSS CCCCCCCCCHHHCCC	45.79	23312004
559	Phosphorylation	STNQQDFSSGKSEDL CCCHHHCCCCCCCCC	46.61	28348404
560	Phosphorylation	TNQQDFSSGKSEDLG CCHHHCCCCCCCCCC	50.67	28348404
562	Ubiquitination	QQDFSSGKSEDLGTV HHHCCCCCCCCCCCC	53.25	21906983
562 (in isoform 1)	Ubiquitination	-	53.25	21906983
562 (in isoform 2)	Ubiquitination	-	53.25	21906983
562 (in isoform 3)	Ubiquitination	-	53.25	21906983
562 (in isoform 4)	Ubiquitination	-	53.25	21906983
563	Phosphorylation	QDFSSGKSEDLGTVQ HHCCCCCCCCCCCCC	39.61	28985074
568	Phosphorylation	GKSEDLGTVQEKSTK CCCCCCCCCCCCCCC	26.72	17924679
572	Ubiquitination	DLGTVQEKSTKSLVI CCCCCCCCCCCEEEE	46.46	-
574	Phosphorylation	GTVQEKSTKSLVIGP CCCCCCCCCEEEEEC	35.40	17924679
575	Ubiquitination	TVQEKSTKSLVIGPL CCCCCCCCEEEEECC	49.21	-
606	Phosphorylation	VCALEHEYEPYSRLK HHHHHCCCCCHHHCC	24.90	22210691
610	Phosphorylation	EHEYEPYSRLKSDIK HCCCCCHHHCCCCCC	41.68	22210691
680	Phosphorylation	SSNFMNTTNFQSLRP CCCCCCCCCCCCCCC	29.09	25599653
684	Phosphorylation	MNTTNFQSLRPLPSI CCCCCCCCCCCCCCE	23.39	24719451
690	Phosphorylation	QSLRPLPSIRILVDK CCCCCCCCEEEEEEC	31.98	24719451
764	Ubiquitination	VPVIPSFSTALYGKL CCCCCCCHHHHHHHH	19.67	22817900
773	Ubiquitination	ALYGKLLKLPTCWTK HHHHHHHCCCCCCCC	63.96	-
808	Ubiquitination	TRAQTLLLQAIYQSW HHHHHHHHHHHHHHH	3.48	22817900
813	Ubiquitination	LLLQAIYQSWSHLGN HHHHHHHHHHCCCCC	32.10	22817900
873	Ubiquitination	VKCASGTMGSIKICA EECCCCCCCEEEEEE	4.52	27667366
882	Ubiquitination	SIKICAKAPVDSGKE EEEEEEECCCCCCCC	7.27	22817900
887	Ubiquitination	AKAPVDSGKEKLIPL EECCCCCCCCCCHHH	37.36	22817900
901	Phosphorylation	LLQGPSDTKDLHSTK HHCCCCCCCCCCCCC	30.69	-
907	Phosphorylation	DTKDLHSTKWLNESR CCCCCCCCCCCCCCC	18.58	23403867
999	Phosphorylation	RRKEDEVSIGSAPLA CCCCCCCEECCCCCH	21.13	25159151
1002	Phosphorylation	EDEVSIGSAPLAKQQ CCCCEECCCCCHHHH	25.66	20164059
1007	Ubiquitination	IGSAPLAKQQSYQAS ECCCCCHHHHCCCHH	57.46	29967540
1010	Phosphorylation	APLAKQQSYQASEYA CCCHHHHCCCHHHHC	19.40	28450419
1011	Phosphorylation	PLAKQQSYQASEYAS CCHHHHCCCHHHHCC	12.08	28985074
1014	Phosphorylation	KQQSYQASEYASSPV HHHCCCHHHHCCCCC	18.67	28450419
1016	Phosphorylation	QSYQASEYASSPVKT HCCCHHHHCCCCCCC	14.86	28450419
1018	Phosphorylation	YQASEYASSPVKTKT CCHHHHCCCCCCCCE	33.98	25159151
1019	Phosphorylation	QASEYASSPVKTKTV CHHHHCCCCCCCCEE	26.07	28450419
1022	Ubiquitination	EYASSPVKTKTVTES HHCCCCCCCCEECCC	47.92	29967540
1023	Phosphorylation	YASSPVKTKTVTESR HCCCCCCCCEECCCC	31.98	28348404
1025	Phosphorylation	SSPVKTKTVTESRPL CCCCCCCEECCCCCC	37.58	23312004
1027	Phosphorylation	PVKTKTVTESRPLSV CCCCCEECCCCCCCC	33.21	23186163
1029	Phosphorylation	KTKTVTESRPLSVPV CCCEECCCCCCCCCH	29.81	25159151
1033	Phosphorylation	VTESRPLSVPVKAML ECCCCCCCCCHHHHC	27.36	28450419
1043	Phosphorylation	VKAMLNISESCRSPE HHHHCCCCHHCCCHH	23.53	30624053
1045	Phosphorylation	AMLNISESCRSPEER HHCCCCHHCCCHHHH	14.19	29214152
1048	Phosphorylation	NISESCRSPEERMKE CCCHHCCCHHHHHHH	40.78	30624053
1188	Phosphorylation	CTSTLAVTSQKLLAT CCHHEEEECHHHHHC	21.60	24667141
1189	Phosphorylation	TSTLAVTSQKLLATG CHHEEEECHHHHHCC	20.79	24667141
1195	Phosphorylation	TSQKLLATGPDTRHS ECHHHHHCCCCCCCE	49.57	24667141
1239	Ubiquitination	IMNKVWNKIQKRGNL HHHHHHHHHHHHCCC	30.70	29967540
1249	Phosphorylation	KRGNLNLSPTSPETM HHCCCCCCCCCCCCC	25.67	23186163
1251	Phosphorylation	GNLNLSPTSPETMAG CCCCCCCCCCCCCCC	54.24	28450419
1251	Ubiquitination	GNLNLSPTSPETMAG CCCCCCCCCCCCCCC	54.24	22817900
1252	Phosphorylation	NLNLSPTSPETMAGP CCCCCCCCCCCCCCC	24.91	28450419
1255	Phosphorylation	LSPTSPETMAGPVPT CCCCCCCCCCCCCCC	18.72	28450419
1256	Ubiquitination	SPTSPETMAGPVPTS CCCCCCCCCCCCCCC	3.75	22817900
1262	Phosphorylation	TMAGPVPTSPVRSSI CCCCCCCCCCCHHHC	45.99	29255136
1263	Phosphorylation	MAGPVPTSPVRSSIG CCCCCCCCCCHHHCC	18.48	29255136
1334	Phosphorylation	QWVLPKITIKLFAPD EEHHHCEEEEEECCC	20.41	24719451
1397	Ubiquitination	ECWSLGQCGGVFLSC HCHHCCCCCCEEEEC	4.93	22817900
1425	Phosphorylation	ISKQDPFSNCSGFFP CCCCCCCCCCCCCCC	42.17	24043423
1428	Phosphorylation	QDPFSNCSGFFPSTT CCCCCCCCCCCCCCC	42.77	24043423
1433	Phosphorylation	NCSGFFPSTTTKLLD CCCCCCCCCCEEECC	32.98	24043423
1434	Phosphorylation	CSGFFPSTTTKLLDG CCCCCCCCCEEECCC	38.43	24043423
1435	Phosphorylation	SGFFPSTTTKLLDGT CCCCCCCCEEECCCC	26.69	24043423
1436	Phosphorylation	GFFPSTTTKLLDGTH CCCCCCCEEECCCCC	21.56	24043423
1506	Ubiquitination	FDIVLYFPLLNAIAS HHHHHHHHHHHHHHH	23.52	27667366
1529	Phosphorylation	TQKEKRKSPGQPMRT CHHHHCCCCCCCCCC	37.99	-
1564	Sulfoxidation	FIPKTEEMQPTVEAN EECCCCCCCCCCCHH	4.75	21406390
1606	Phosphorylation	SVLRKDIYQRALNLG HHHHHHHHHHHHCCC	11.33	22817900
1627	Phosphorylation	SEIEDRQYQIDLQSI CCCCCCEEEEEEEEC	14.34	24043423
1633	Phosphorylation	QYQIDLQSINIGTAQ EEEEEEEECEECCCC	25.54	24043423
1638	Phosphorylation	LQSINIGTAQWHQLK EEECEECCCCCEECC	16.33	24043423
1663	Phosphorylation	VTETERNSQNPALEW ECCCCCCCCCCCHHH	37.24	26503514
1674	Phosphorylation	ALEWNMASSIRRHQE CHHHHHHHHHHHHHH	18.61	20363803
1675	Phosphorylation	LEWNMASSIRRHQER HHHHHHHHHHHHHHH	15.58	20363803
1676	Ubiquitination	EWNMASSIRRHQERR HHHHHHHHHHHHHHH	4.09	22817900
1687	Phosphorylation	QERRAILTPVLTDFS HHHHHHHHHHHCCCE	12.77	-
1737	Ubiquitination	ITTNLDFFLSVAQVQ EECCHHHHHHHHHHH	5.05	22817900
1773	Ubiquitination	ISKQEQKKVDIFDGG HHHHHHCCCCCCCCC	44.85	-
1776	Ubiquitination	QEQKKVDIFDGGMAE HHHCCCCCCCCCCCC	3.67	22817900
1777	Ubiquitination	EQKKVDIFDGGMAET HHCCCCCCCCCCCCC	6.55	22817900
1777 (in isoform 2)	Ubiquitination	-	6.55	21906983
1785	Ubiquitination	DGGMAETSSRYSGAQ CCCCCCCCCCCCCCC	12.34	27667366
1788	Phosphorylation	MAETSSRYSGAQDSG CCCCCCCCCCCCCCC	17.26	27251275
1789	Phosphorylation	AETSSRYSGAQDSGI CCCCCCCCCCCCCCC	26.92	23090842
1794	Phosphorylation	RYSGAQDSGIGSDSV CCCCCCCCCCCCCCE	21.89	28450419
1798	Phosphorylation	AQDSGIGSDSVKIRI CCCCCCCCCCEEEEE	25.45	25159151
1800	Phosphorylation	DSGIGSDSVKIRIVQ CCCCCCCCEEEEEEE	27.32	28450419
1801	Ubiquitination	SGIGSDSVKIRIVQI CCCCCCCEEEEEEEE	7.78	22817900
1802	Ubiquitination	GIGSDSVKIRIVQIE CCCCCCEEEEEEEEE	30.16	21906983
1802 (in isoform 1)	Ubiquitination	-	30.16	21906983
1812	Phosphorylation	IVQIEQHSGASQHRI EEEEEECCCCCCCCC	35.43	30266825
1815	Phosphorylation	IEQHSGASQHRIARP EEECCCCCCCCCCCC	30.00	30266825
1826	Phosphorylation	IARPSRQSSIVKNLN CCCCCCCCCHHHCCC	22.41	23186163
1846	Ubiquitination	IFITASRISLMTYSC EEEEEHHHHHHHHHH	3.25	27667366
1847	Phosphorylation	FITASRISLMTYSCM EEEEHHHHHHHHHHH	15.81	-
1852	Phosphorylation	RISLMTYSCMALSKS HHHHHHHHHHHHHCC	6.56	-
1884	Ubiquitination	LPEVDSDVAKPNQAC CCCCCCCCCCCCCCE	9.50	22817900
1885	Ubiquitination	PEVDSDVAKPNQACI CCCCCCCCCCCCCEE	26.95	27667366
1886	Ubiquitination	EVDSDVAKPNQACIS CCCCCCCCCCCCEEE	44.33	27667366
1889	Ubiquitination	SDVAKPNQACISTVT CCCCCCCCCEEEEEC	46.25	22817900
1904	Phosphorylation	AEDLLRSSISFPSGK HHHHHHHCCCCCCCC	18.80	22985185
1910	Ubiquitination	SSISFPSGKKIGVLS HCCCCCCCCEEEEEE	35.20	27667366
1911	Ubiquitination	SISFPSGKKIGVLSL CCCCCCCCEEEEEEH	45.62	27667366
1967	Ubiquitination	SQPSLLLSCHHRKQR CCCCHHHHCCCCCCC	16.04	29967540
1978	Phosphorylation	RKQRVEVSIFDAVLK CCCCEEEEHHHHHHH	12.20	-
1989	Phosphorylation	AVLKGVASDYKCIDP HHHHHHHCCCCCCCC	38.78	29396449
1991	Phosphorylation	LKGVASDYKCIDPGK HHHHHCCCCCCCCCC	12.79	29396449
1992	Ubiquitination	KGVASDYKCIDPGKT HHHHCCCCCCCCCCC	36.73	29967540
2048	Phosphorylation	ADVNLDISKPLKANL CCCCCCCCCCCCCCC	28.08	24719451
2052	Methylation	LDISKPLKANLSFTK CCCCCCCCCCCCCCC	43.70	115978777
2056	Phosphorylation	KPLKANLSFTKLDQI CCCCCCCCCCCHHHH	30.58	24719451
2074	Ubiquitination	LKKIKNAHSLAHSEE HHHHHCHHHHHCCCC	32.51	33845483
2075	Phosphorylation	KKIKNAHSLAHSEET HHHHCHHHHHCCCCC	25.49	29978859
2079	Phosphorylation	NAHSLAHSEETSAMS CHHHHHCCCCCHHHC	31.36	29978859
2082	Phosphorylation	SLAHSEETSAMSNTM HHHCCCCCHHHCCCC	20.10	29978859
2083	Phosphorylation	LAHSEETSAMSNTMV HHCCCCCHHHCCCCC	25.84	29978859
2086	Phosphorylation	SEETSAMSNTMVNKD CCCCHHHCCCCCCCC	28.94	29978859
2088	Phosphorylation	ETSAMSNTMVNKDDL CCHHHCCCCCCCCCC	18.39	29978859
2098	Phosphorylation	NKDDLPVSKYYRGKL CCCCCCHHHHCCCCC	17.01	29978859
2099	Ubiquitination	KDDLPVSKYYRGKLS CCCCCHHHHCCCCCC	46.68	33845483
2100	Phosphorylation	DDLPVSKYYRGKLSK CCCCHHHHCCCCCCC	7.29	29978859
2101	Phosphorylation	DLPVSKYYRGKLSKP CCCHHHHCCCCCCCC	19.34	29978859
2103	Ubiquitination	PVSKYYRGKLSKPKI CHHHHCCCCCCCCEE	21.09	27667366
2106	Phosphorylation	KYYRGKLSKPKIHGD HHCCCCCCCCEECCC	50.85	24719451
2163	Ubiquitination	LLASLSNLNGSLSVK HHHHHHCCCCCCCCC	7.44	22817900
2166	Phosphorylation	SLSNLNGSLSVKATQ HHHCCCCCCCCCCCC	19.19	24719451
2168	Ubiquitination	SNLNGSLSVKATQKV HCCCCCCCCCCCCCC	24.22	22817900
2177	Ubiquitination	KATQKVPGIILGSSF CCCCCCCCEEECHHH	23.66	27667366
2222	Phosphorylation	EAKWCKHSGNPGPEQ HHHHHHCCCCCCCCC	26.26	22817900
2224	Ubiquitination	KWCKHSGNPGPEQSI HHHHCCCCCCCCCCC	41.17	22817900
2229	Ubiquitination	SGNPGPEQSIPKISI CCCCCCCCCCCEEEE	50.20	22817900
2235	Phosphorylation	EQSIPKISIDLRGGL CCCCCEEEEECCCCE	19.04	22817900
2263	Ubiquitination	VLLHELLNGYLNEEG HHHHHHHHCCCCCCC	50.08	22817900
2264	Ubiquitination	LLHELLNGYLNEEGN HHHHHHHCCCCCCCC	28.42	22817900
2268	Ubiquitination	LLNGYLNEEGNFEVQ HHHCCCCCCCCEEEE	65.76	22817900
2269	Ubiquitination	LNGYLNEEGNFEVQV HHCCCCCCCCEEEEE	59.36	22817900
2269 (in isoform 2)	Ubiquitination	-	59.36	21906983
2284	Phosphorylation	SEPVPQMSSPVEKNQ CCCCCCCCCCCCCCC	26.66	24275569
2288	Ubiquitination	PQMSSPVEKNQTFKS CCCCCCCCCCCCCCC	50.07	22817900
2289	Ubiquitination	QMSSPVEKNQTFKSE CCCCCCCCCCCCCCC	55.37	22817900
2293	Ubiquitination	PVEKNQTFKSEQSSD CCCCCCCCCCCCCCH	6.20	22817900
2294	Ubiquitination	VEKNQTFKSEQSSDD CCCCCCCCCCCCCHH	57.37	21906983
2294 (in isoform 1)	Ubiquitination	-	57.37	21906983
2341	Phosphorylation	PGMMLWRYPEPRVLT CCCEEECCCCCCEEE	10.60	28509920
2348	Phosphorylation	YPEPRVLTLVRITPV CCCCCEEEEEEEECC	21.98	28509920
2419	Ubiquitination	NLVNDQKKLVSSDLW CCCCCCHHHHCCHHH	48.79	-
2450	Ubiquitination	ASESGSQSTCDPLVT CCCCCCCCCCCCCCC	32.47	22817900
2524	Ubiquitination	PSELEYMIVSFREPH CCCCEEEEEECCCCC	1.99	22817900
2541	Phosphorylation	LRQWNNGSVCQEIQF EECCCCCCHHHHHHH	23.11	-
2546	Ubiquitination	NGSVCQEIQFLAQAD CCCHHHHHHHHHHCC	1.13	27667366
2710	Phosphorylation	QYRGRTASLIIKVQQ EECCCEEEEEEEHHH	21.35	24247654
2743	Ubiquitination	YLSQSIELKVVQHYI HHHHCEEEEEEHHHC	4.93	29967540
2768	Ubiquitination	HFDCLTAKQKLPSYI HHHHCHHHCCCCHHH	42.61	29967540
2773	Phosphorylation	TAKQKLPSYILENNE HHHCCCCHHHCCCCC	34.93	-
2774	Phosphorylation	AKQKLPSYILENNEL HHCCCCHHHCCCCCC	13.95	-
2856	Ubiquitination	MRSHLPDPIIIHLEK HHHCCCCCEEEEEEC	20.10	29967540
2881	Ubiquitination	IPGKGQEKPLQNIEP CCCCCCCCCCCCCCC	43.04	29967540
2892	Ubiquitination	NIEPDLVHHLTFQAR CCCCCHHHHHEEECC	19.96	29967540
2893	Ubiquitination	IEPDLVHHLTFQARE CCCCHHHHHEEECCC	21.05	22817900
2897	Ubiquitination	LVHHLTFQAREEYDP HHHHHEEECCCCCCC	33.98	29967540
2905	Phosphorylation	AREEYDPSDCAVPIS CCCCCCCCCCCCEEC	42.28	-
2914	Phosphorylation	CAVPISTSLIKQIAT CCCEECHHHHHHHHH	22.70	24719451
2917	Ubiquitination	PISTSLIKQIATKVH EECHHHHHHHHHCCC	40.73	29967540
2922	Ubiquitination	LIKQIATKVHPGGTV HHHHHHHCCCCCCHH	29.53	29967540
2926	Ubiquitination	IATKVHPGGTVNQIL HHHCCCCCCHHHHHH	29.53	29967540
2951	Ubiquitination	QPIWPYNKKDSDRNE CCCCCCCCCCCCCCH	52.71	29967540
2980	Phosphorylation	IWKPYVRTLLIELLP HCHHHHHHHHHHHHH	18.84	22210691
3029	Ubiquitination	FQEAFQIGIYWANTN HHHHHEEEEEEECCC	8.99	29967540
3051	Phosphorylation	IKLVHNLTSPKWKDG HHHHHCCCCCCCCCC	48.58	30108239
3052	Phosphorylation	KLVHNLTSPKWKDGG HHHHCCCCCCCCCCC	27.87	25159151
3054	Ubiquitination	VHNLTSPKWKDGGNG HHCCCCCCCCCCCCC	67.64	29967540
3142	Phosphorylation	EYFRVPDSATFSICP EEEECCCCCEEEECC	24.12	30631047
3146	Phosphorylation	VPDSATFSICPGGEQ CCCCCEEEECCCCCC	20.94	30631047
3179	Ubiquitination	QSVLDASLLQKQIML HHHHCHHHHHHHHHH	6.69	27667366
3251	Ubiquitination	YLTLSEDPSPRVIIH EEECCCCCCCCEEEE	42.03	29967540
3268	Acetylation	CPVKMLIKENIKDIP CCHHHHHHHCCCCCC	40.52	7851271
3276	Ubiquitination	ENIKDIPKFEVYCKK HCCCCCCCCEEEECC	55.26	29967540
3458	Ubiquitination	DLQLDNQLYNKSNFH CCCHHCCHHCCCCCE	6.79	27667366
3482	Phosphorylation	KAEPIQCSKMQSLLI CCCCCCCCHHHHEEC	18.13	-
3483	Ubiquitination	AEPIQCSKMQSLLIS CCCCCCCHHHHEECC	48.89	29967540
3486	Phosphorylation	IQCSKMQSLLISNKE CCCCHHHHEECCCHH	22.96	23403867
3490	Phosphorylation	KMQSLLISNKELEEY HHHHEECCCHHHHHH	41.65	-
3498	Acetylation	NKELEEYKEKCFIKL CHHHHHHHHHHEEEE	54.71	18529111
3500	Acetylation	ELEEYKEKCFIKLCI HHHHHHHHHEEEEEE	30.23	18529119
3519	Ubiquitination	GKSILCDINEFSFEL CCEEEEECCCCEEEE	5.33	27667366
3526	Ubiquitination	INEFSFELKPARLYV CCCCEEEECCCEEEE	8.30	22817900
3532	Phosphorylation	ELKPARLYVEDTFVY EECCCEEEEEHHHHH	9.02	27251275
3536	Phosphorylation	ARLYVEDTFVYYIKT CEEEEEHHHHHHHHH	11.07	18452278
3540	Phosphorylation	VEDTFVYYIKTLFDT EEHHHHHHHHHHHHC	7.22	18452278
3547	Phosphorylation	YIKTLFDTYLPNSRL HHHHHHHCCCCCCCC	21.44	27251275
3548	Phosphorylation	IKTLFDTYLPNSRLA HHHHHHCCCCCCCCC	23.23	27251275
3552	Phosphorylation	FDTYLPNSRLAGHST HHCCCCCCCCCCCCC	27.08	27251275
3558	Phosphorylation	NSRLAGHSTHLSGGK CCCCCCCCCCCCCCC	19.32	24719451
3558	Ubiquitination	NSRLAGHSTHLSGGK CCCCCCCCCCCCCCC	19.32	27667366
3559	Phosphorylation	SRLAGHSTHLSGGKQ CCCCCCCCCCCCCCE	22.59	24719451
3559	Ubiquitination	SRLAGHSTHLSGGKQ CCCCCCCCCCCCCCE	22.59	27667366
3573	Phosphorylation	QVLPMQVTQHARALV EEECCHHHHHHHHHC	9.57	-
3583	Ubiquitination	ARALVNPVKLRKLVI HHHHCCHHHHHHEEE	8.44	27667366
3584	Ubiquitination	RALVNPVKLRKLVIQ HHHCCHHHHHHEEEE	43.78	27667366
3617	Phosphorylation	DHTPLSFSVFERGPI CCCCCCEEECCCCCC	23.63	24719451
3679	Phosphorylation	ADFFRLPYEGLTRGP HHHHCCCCCCCCCCC	27.50	25599653
3708	Phosphorylation	VKHISKGTLTSITNL HHHCCCCCHHHHHHH	30.51	-
3710	Phosphorylation	HISKGTLTSITNLAT HCCCCCHHHHHHHHH	20.23	-
3733	Phosphorylation	LSLDEEHYNRQEEWR CCCCHHHHHHHHHHH	18.47	27642862
3767	Ubiquitination	ISLLGAIAGIVDQPM HHHHHHHHHHCCHHH	10.92	29967540
3792	Ubiquitination	ASAGHKAKGVISGVG HHHCHHHHHCEECCC	59.52	29967540
3805	Ubiquitination	VGKGIMGVFTKPIGG CCCCCCEEECCCCCC	2.81	22817900
3810	Ubiquitination	MGVFTKPIGGAAELV CEEECCCCCCHHHHH	9.42	29967540
3829	Ubiquitination	YGILHGAGLSQLPKQ CCHHCCCCHHHCCCC	30.38	29967540
3835	Ubiquitination	AGLSQLPKQRHQPSD CCHHHCCCCCCCCCC	69.43	29967540
3854	Ubiquitination	QAPNSHVKYVWKMLQ CCCCHHHHHHHHHHH	28.76	29967540
3866	Ubiquitination	MLQSLGRPEVHMALD HHHHCCCCHHHEEEE	46.28	22817900
3905	Ubiquitination	VSVSEDTQQQAFPVT EECCCCCCCCCCCCC	45.79	22817900
3906	Ubiquitination	SVSEDTQQQAFPVTE ECCCCCCCCCCCCCE	38.37	22817900
3906 (in isoform 2)	Ubiquitination	-	38.37	21906983
3930	Ubiquitination	NNLLTVQLKQPRVAC CCEEEEEECCCCEEC	4.90	22817900
3931	Ubiquitination	NLLTVQLKQPRVACD CEEEEEECCCCEECE	40.96	22817900
3931 (in isoform 1)	Ubiquitination	-	40.96	21906983
3949	Phosphorylation	DGVRERLSEQQYNRL CCHHHHHCHHHHHHH	39.31	23312004
3953	Phosphorylation	ERLSEQQYNRLVDYI HHHCHHHHHHHHHHH	11.27	23312004

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VP13B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VP13B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VP13B_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of VP13B_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 216550: Cohen syndrome (COH1)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.;
Anal. Sci. 24:161-166(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2222 AND SER-2235, ANDMASS SPECTROMETRY.
PubMed: 18187866

"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.;
J. Proteome Res. 6:4150-4162(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-563; THR-568 ANDTHR-574, AND MASS SPECTROMETRY.
PubMed: 17924679

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-999 AND SER-1002, ANDMASS SPECTROMETRY.
PubMed: 17081983