| UniProt ID | K0408_HUMAN | |
|---|---|---|
| UniProt AC | Q6ZU52 | |
| Protein Name | Uncharacterized protein KIAA0408 | |
| Gene Name | KIAA0408 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 694 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MDLHKQWENTETNWHKEKMELLDQFDNERKEWESQWKIMQKKIEELCREVKLWRKININESAKIIDLYHEKTIPEKVIESSPNYPDLGQSEFIRTNHKDGLRKENKREQSLVSGGNQMCKEQKATKKSKVGFLDPLATDNQKECEAWPDLRTSEEDSKSCSGALSTALEELAKVSEELCSFQEEIRKRSNHRRMKSDSFLQEMPNVTNIPHGDPMINNDQCILPISLEKEKQKNRKNLSCTNVLQSNSTKKCGIDTIDLKRNETPPVPPPRSTSRNFPSSDSEQAYERWKERLDHNSWVPHEGRSKRNYNPHFPLRQQEMSMLYPNEGKTSKDGIIFSSLVPEVKIDSKPPSNEDVGLSMWSCDIGIGAKRSPSTSWFQKTCSTPSNPKYEMVIPDHPAKSHPDLHVSNDCSSSVAESSSPLRNFSCGFERTTRNEKLAAKTDEFNRTVFRTDRNCQAIQQNHSCSKSSEDLKPCDTSSTHTGSISQSNDVSGIWKTNAHMPVPMENVPDNPTKKSTTGLVRQMQGHLSPRSYRNMLHEHDWRPSNLSGRPRSADPRSNYGVVEKLLKTYETATESALQNSKCFQDNWTKCNSDVSGGATLSQHLEMLQMEQQFQQKTAVWGGQEVKQGIDPKKITEESMSVNASHGKGFSRPARPANRRLPSRWASRSPSAPPALRRTTHNYTISLRSEALMV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 6 (in isoform 2) | Ubiquitination | - | 41.80 | 21906983 | |
| 9 (in isoform 2) | Ubiquitination | - | 40.01 | 21906983 | |
| 51 | Ubiquitination | EELCREVKLWRKINI HHHHHHHHHHHHCCC | 37.26 | - | |
| 61 | Phosphorylation | RKININESAKIIDLY HHCCCCCCCEEECCH | 30.30 | - | |
| 68 | Phosphorylation | SAKIIDLYHEKTIPE CCEEECCHHCCCCCH | 12.27 | - | |
| 110 | Phosphorylation | KENKREQSLVSGGNQ CCCHHHHHHHCCHHH | 26.45 | 29449344 | |
| 113 | Phosphorylation | KREQSLVSGGNQMCK HHHHHHHCCHHHHHH | 46.40 | 29449344 | |
| 123 | Ubiquitination | NQMCKEQKATKKSKV HHHHHHHHCCCCCCC | 60.15 | 21906983 | |
| 126 | Ubiquitination | CKEQKATKKSKVGFL HHHHHCCCCCCCCCC | 60.97 | 2190698 | |
| 159 | Phosphorylation | TSEEDSKSCSGALST CCHHHHHHHHHHHHH | 19.91 | 27251275 | |
| 161 | Phosphorylation | EEDSKSCSGALSTAL HHHHHHHHHHHHHHH | 33.90 | 27251275 | |
| 241 | Phosphorylation | NRKNLSCTNVLQSNS CCCCCCHHHHHCCCC | 25.61 | - | |
| 248 | Phosphorylation | TNVLQSNSTKKCGID HHHHCCCCCCCCCCE | 47.02 | - | |
| 273 | Phosphorylation | PVPPPRSTSRNFPSS CCCCCCCCCCCCCCC | 32.74 | 23403867 | |
| 274 | Phosphorylation | VPPPRSTSRNFPSSD CCCCCCCCCCCCCCC | 26.86 | 23403867 | |
| 324 | Phosphorylation | QQEMSMLYPNEGKTS HHHHHCCCCCCCCCC | 8.72 | 24719451 | |
| 330 | Phosphorylation | LYPNEGKTSKDGIIF CCCCCCCCCCCCEEE | 52.44 | 24719451 | |
| 331 | Phosphorylation | YPNEGKTSKDGIIFS CCCCCCCCCCCEEEC | 32.03 | - | |
| 338 | Phosphorylation | SKDGIIFSSLVPEVK CCCCEEECCCCCCEE | 16.62 | 20058876 | |
| 401 | Phosphorylation | IPDHPAKSHPDLHVS CCCCCCCCCCCCCCC | 42.21 | - | |
| 418 | Phosphorylation | CSSSVAESSSPLRNF CCCHHHHCCCCCCCC | 26.78 | 23312004 | |
| 419 | Phosphorylation | SSSVAESSSPLRNFS CCHHHHCCCCCCCCC | 27.72 | 23312004 | |
| 420 | Phosphorylation | SSVAESSSPLRNFSC CHHHHCCCCCCCCCC | 36.91 | 23312004 | |
| 451 | Methylation | EFNRTVFRTDRNCQA CHHHHHHHCHHHHHH | 31.23 | 24377405 | |
| 451 | Dimethylation | EFNRTVFRTDRNCQA CHHHHHHHCHHHHHH | 31.23 | - | |
| 517 | Phosphorylation | DNPTKKSTTGLVRQM CCCCCCCHHHHHHHH | 33.49 | 27174698 | |
| 518 | Phosphorylation | NPTKKSTTGLVRQMQ CCCCCCHHHHHHHHC | 35.29 | 27174698 | |
| 529 | Phosphorylation | RQMQGHLSPRSYRNM HHHCCCCCHHHHHHH | 16.76 | 27174698 | |
| 532 | Phosphorylation | QGHLSPRSYRNMLHE CCCCCHHHHHHHHHH | 31.65 | 27174698 | |
| 533 | Phosphorylation | GHLSPRSYRNMLHEH CCCCHHHHHHHHHHC | 13.79 | 27174698 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of K0408_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of K0408_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of K0408_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CEP72_HUMAN | CEP72 | physical | 16189514 | |
| VINEX_HUMAN | SORBS3 | physical | 16189514 | |
| TEX11_HUMAN | TEX11 | physical | 16189514 | |
| ABI3_HUMAN | ABI3 | physical | 16189514 | |
| BEGIN_HUMAN | BEGAIN | physical | 16189514 | |
| HOOK2_HUMAN | HOOK2 | physical | 16189514 | |
| CC85B_HUMAN | CCDC85B | physical | 16189514 | |
| CARD9_HUMAN | CARD9 | physical | 16189514 | |
| KDM1A_HUMAN | KDM1A | physical | 23455924 | |
| ANM6_HUMAN | PRMT6 | physical | 23455924 | |
| VINEX_HUMAN | SORBS3 | physical | 25416956 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
