| UniProt ID | SNT1_YEAST | |
|---|---|---|
| UniProt AC | P25357 | |
| Protein Name | Probable DNA-binding protein SNT1 | |
| Gene Name | SNT1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 1226 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Part of the Set3C complex, which is required to repress early/middle sporulation genes during meiosis.. | |
| Protein Sequence | MGYPPPTRRLGDKKRYHYSNNPNRRHPSAVYSKNSFPKSSNNGFVSSPTADNSTNPSVTPSTASVPLPTAAPGSTFGIEAPRPSRYDPSSVSRPSSSSYSSTRKIGSRYNPDVERSSSTTSSTPESMNTSTITHTNTDIGNSRYSRKTMSRYNPQSTSSTNVTHFPSALSNAPPFYVANGSSRRPRSMDDYSPDVTNKLETNNVSSVNNNSPHSYYSRSNKWRSIGTPSRPPFDNHVGNMTTTSNTNSIHQREPFWKANSTTILKSTHSQSSPSLHTKKFHDANKLDKPEASVKVETPSKDETKAISYHDNNFPPRKSVSKPNAPLEPDNIKVGEEDALGKKEVHKSGREIAKEHPTPVKMKEHDELEARAKKVSKINIDGKQDEIWTTAKTVASAVEVSKESQKELTRSVERKESPEIRDYERAYDPKALKTDVTKLTVDNDNKSYEEPLEKVEGCIFPLPKAETRLWELKNQKRNKIISEQKYLLKKAIRNFSEYPFYAQNKLIHQQATGLILTKIISKIKKEEHLKKINLKHDYFDLQKKYEKECEILTKLSENLRKEEIENKRKEHELMEQKRREEGIETEKEKSLRHPSSSSSSRRRNRADFVDDAEMENVLLQIDPNYKHYQAAATIPPLILDPIRKHSYKFCDVNNLVTDKKLWASRILKDASDNFTDHEHSLFLEGYLIHPKKFGKISHYMGGLRSPEECVLHYYRTKKTVNYKQLLIDKNKKRKMSAAAKRRKRKERSNDEEVEVDESKEESTNTIEKEEKSENNAEENVQPVLVQGSEVKGDPLGTPEKVENMIEQRGEEFAGELENAERVNDLKRAHDEVGEESNKSSVIETNNGVQIMDPKGAVQNGYYPEETKELDFSLENALQRKKHKSAPEHKTSYWSVRESQLFPELLKEFGSQWSLISEKLGTKSTTMVRNYYQRNAARNGWKLLVDETDLKRDGTSSESVQQSQILIQPERPNINAYSNIPPQQRPALGYFVGQPTHGHNTSISSIDGSIRPFGPDFHRDTFSKISAPLTTLPPPRLPSIQFPRSEMAEPTVTDLRNRPLDHIDTLADAASSVTNNQNFSNERNAIDIGRKSTTISNLLNNSDRSMKSSFQSASRHEAQLEDTPSMNNIVVQEIKPNITTPRSSSISALLNPVNGNGQSNPDGRPLLPFQHAISQGTPTFPLPAPRTSPISRAPPKFNFSNDPLAALAAVASAPDAMSSFLSKKENNN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 33 | Acetylation | HPSAVYSKNSFPKSS CCCCCCCCCCCCCCC | 38.63 | 22865919 | |
| 86 | Phosphorylation | EAPRPSRYDPSSVSR CCCCCCCCCCCCCCC | 36.22 | 28889911 | |
| 92 | Phosphorylation | RYDPSSVSRPSSSSY CCCCCCCCCCCCCCC | 40.18 | 28889911 | |
| 95 | Phosphorylation | PSSVSRPSSSSYSST CCCCCCCCCCCCCCC | 41.56 | 28889911 | |
| 96 | Phosphorylation | SSVSRPSSSSYSSTR CCCCCCCCCCCCCCC | 26.45 | 28889911 | |
| 116 | Phosphorylation | YNPDVERSSSTTSST CCCCCCCCCCCCCCC | 18.35 | 22369663 | |
| 117 | Phosphorylation | NPDVERSSSTTSSTP CCCCCCCCCCCCCCC | 37.61 | 22369663 | |
| 118 | Phosphorylation | PDVERSSSTTSSTPE CCCCCCCCCCCCCCC | 36.63 | 22369663 | |
| 119 | Phosphorylation | DVERSSSTTSSTPES CCCCCCCCCCCCCCC | 32.42 | 22369663 | |
| 120 | Phosphorylation | VERSSSTTSSTPESM CCCCCCCCCCCCCCC | 23.72 | 22369663 | |
| 121 | Phosphorylation | ERSSSTTSSTPESMN CCCCCCCCCCCCCCC | 32.10 | 22369663 | |
| 122 | Phosphorylation | RSSSTTSSTPESMNT CCCCCCCCCCCCCCC | 45.98 | 22369663 | |
| 123 | Phosphorylation | SSSTTSSTPESMNTS CCCCCCCCCCCCCCC | 30.73 | 23749301 | |
| 126 | Phosphorylation | TTSSTPESMNTSTIT CCCCCCCCCCCCCEE | 20.66 | 22369663 | |
| 129 | Phosphorylation | STPESMNTSTITHTN CCCCCCCCCCEEECC | 20.71 | 22369663 | |
| 130 | Phosphorylation | TPESMNTSTITHTNT CCCCCCCCCEEECCC | 16.89 | 22369663 | |
| 131 | Phosphorylation | PESMNTSTITHTNTD CCCCCCCCEEECCCC | 28.05 | 22369663 | |
| 133 | Phosphorylation | SMNTSTITHTNTDIG CCCCCCEEECCCCCC | 23.80 | 22369663 | |
| 135 | Phosphorylation | NTSTITHTNTDIGNS CCCCEEECCCCCCCC | 31.03 | 22369663 | |
| 137 | Phosphorylation | STITHTNTDIGNSRY CCEEECCCCCCCCCC | 30.10 | 22369663 | |
| 142 | Phosphorylation | TNTDIGNSRYSRKTM CCCCCCCCCCCCCCH | 27.64 | 22369663 | |
| 152 | Phosphorylation | SRKTMSRYNPQSTSS CCCCHHHCCCCCCCC | 24.72 | 22369663 | |
| 156 | Phosphorylation | MSRYNPQSTSSTNVT HHHCCCCCCCCCCCC | 31.36 | 22369663 | |
| 157 | Phosphorylation | SRYNPQSTSSTNVTH HHCCCCCCCCCCCCC | 22.81 | 22369663 | |
| 158 | Phosphorylation | RYNPQSTSSTNVTHF HCCCCCCCCCCCCCC | 40.17 | 22369663 | |
| 159 | Phosphorylation | YNPQSTSSTNVTHFP CCCCCCCCCCCCCCC | 24.88 | 22369663 | |
| 160 | Phosphorylation | NPQSTSSTNVTHFPS CCCCCCCCCCCCCCH | 33.21 | 21440633 | |
| 163 | Phosphorylation | STSSTNVTHFPSALS CCCCCCCCCCCHHHH | 21.62 | 22369663 | |
| 167 | Phosphorylation | TNVTHFPSALSNAPP CCCCCCCHHHHCCCC | 40.68 | 22369663 | |
| 170 | Phosphorylation | THFPSALSNAPPFYV CCCCHHHHCCCCEEE | 30.57 | 22369663 | |
| 176 | Phosphorylation | LSNAPPFYVANGSSR HHCCCCEEECCCCCC | 12.39 | 22369663 | |
| 181 | Phosphorylation | PFYVANGSSRRPRSM CEEECCCCCCCCCCC | 22.07 | 22369663 | |
| 182 | Phosphorylation | FYVANGSSRRPRSMD EEECCCCCCCCCCCC | 33.44 | 22369663 | |
| 187 | Phosphorylation | GSSRRPRSMDDYSPD CCCCCCCCCCCCCCC | 29.28 | 28889911 | |
| 192 | Phosphorylation | PRSMDDYSPDVTNKL CCCCCCCCCCCCCCC | 22.94 | 28889911 | |
| 198 | Acetylation | YSPDVTNKLETNNVS CCCCCCCCCCCCCCC | 38.03 | 24489116 | |
| 205 | Phosphorylation | KLETNNVSSVNNNSP CCCCCCCCCCCCCCC | 30.60 | 30377154 | |
| 206 | Phosphorylation | LETNNVSSVNNNSPH CCCCCCCCCCCCCCC | 25.28 | 19779198 | |
| 211 | Phosphorylation | VSSVNNNSPHSYYSR CCCCCCCCCCCCCCC | 26.55 | 21440633 | |
| 214 | Phosphorylation | VNNNSPHSYYSRSNK CCCCCCCCCCCCCCC | 29.20 | 24961812 | |
| 215 | Phosphorylation | NNNSPHSYYSRSNKW CCCCCCCCCCCCCCC | 11.48 | 19779198 | |
| 217 | Phosphorylation | NSPHSYYSRSNKWRS CCCCCCCCCCCCCCC | 22.47 | 24961812 | |
| 219 | Phosphorylation | PHSYYSRSNKWRSIG CCCCCCCCCCCCCCC | 36.50 | 24961812 | |
| 257 | Acetylation | HQREPFWKANSTTIL CCCCCCHHCCCCEEE | 37.76 | 22865919 | |
| 269 | Phosphorylation | TILKSTHSQSSPSLH EEEECCCCCCCCCCC | 31.67 | 29136822 | |
| 271 | Phosphorylation | LKSTHSQSSPSLHTK EECCCCCCCCCCCCC | 47.43 | 21440633 | |
| 272 | Phosphorylation | KSTHSQSSPSLHTKK ECCCCCCCCCCCCCC | 15.75 | 28132839 | |
| 278 | Acetylation | SSPSLHTKKFHDANK CCCCCCCCCCCCCCC | 42.57 | 25381059 | |
| 279 | Acetylation | SPSLHTKKFHDANKL CCCCCCCCCCCCCCC | 49.43 | 25381059 | |
| 285 | Acetylation | KKFHDANKLDKPEAS CCCCCCCCCCCCCCE | 60.84 | 24489116 | |
| 300 | Acetylation | VKVETPSKDETKAIS EEEECCCCCCCCCEE | 61.87 | 25381059 | |
| 318 | Phosphorylation | NNFPPRKSVSKPNAP CCCCCCCCCCCCCCC | 32.66 | 20377248 | |
| 320 | Phosphorylation | FPPRKSVSKPNAPLE CCCCCCCCCCCCCCC | 49.87 | 28152593 | |
| 353 | Acetylation | KSGREIAKEHPTPVK HHHHHHHHHCCCCCC | 63.32 | 25381059 | |
| 357 | Phosphorylation | EIAKEHPTPVKMKEH HHHHHCCCCCCCCCH | 42.49 | 25521595 | |
| 395 | Phosphorylation | TTAKTVASAVEVSKE HHHHHHHHHHHHCHH | 28.63 | 28889911 | |
| 400 | Phosphorylation | VASAVEVSKESQKEL HHHHHHHCHHHHHHH | 19.73 | 30377154 | |
| 403 | Phosphorylation | AVEVSKESQKELTRS HHHHCHHHHHHHHHH | 50.73 | 30377154 | |
| 410 | Phosphorylation | SQKELTRSVERKESP HHHHHHHHHHHCCCH | 24.08 | 21551504 | |
| 416 | Phosphorylation | RSVERKESPEIRDYE HHHHHCCCHHHHCHH | 30.76 | 29136822 | |
| 481 | Phosphorylation | QKRNKIISEQKYLLK HHHHHHHHHHHHHHH | 37.13 | 21126336 | |
| 484 | Acetylation | NKIISEQKYLLKKAI HHHHHHHHHHHHHHH | 33.54 | 24489116 | |
| 495 | Phosphorylation | KKAIRNFSEYPFYAQ HHHHHHHHCCCHHHC | 39.51 | 25704821 | |
| 517 | Acetylation | ATGLILTKIISKIKK HHHHHHHHHHHHHCC | 34.30 | 22865919 | |
| 534 | Acetylation | HLKKINLKHDYFDLQ HHHHCCCCCCHHHHH | 29.91 | 24489116 | |
| 576 | Acetylation | EHELMEQKRREEGIE HHHHHHHHHHHHCCC | 39.87 | 22865919 | |
| 594 | Phosphorylation | EKSLRHPSSSSSSRR HHHHCCCCCCCHHHH | 36.41 | 28889911 | |
| 597 | Phosphorylation | LRHPSSSSSSRRRNR HCCCCCCCHHHHHHH | 33.99 | 28889911 | |
| 598 | Phosphorylation | RHPSSSSSSRRRNRA CCCCCCCHHHHHHHH | 29.79 | 28889911 | |
| 599 | Phosphorylation | HPSSSSSSRRRNRAD CCCCCCHHHHHHHHH | 31.58 | 28889911 | |
| 696 | Phosphorylation | PKKFGKISHYMGGLR HHHHCCCCHHCCCCC | 16.44 | 27017623 | |
| 698 | Phosphorylation | KFGKISHYMGGLRSP HHCCCCHHCCCCCCH | 7.23 | 23749301 | |
| 704 | Phosphorylation | HYMGGLRSPEECVLH HHCCCCCCHHHHHHH | 41.53 | 23749301 | |
| 712 | Phosphorylation | PEECVLHYYRTKKTV HHHHHHHHHHCCCCC | 7.18 | 27017623 | |
| 713 | Phosphorylation | EECVLHYYRTKKTVN HHHHHHHHHCCCCCC | 10.89 | 27017623 | |
| 739 | Ubiquitination | RKMSAAAKRRKRKER HHHHHHHHHHHHHHH | 48.27 | 22106047 | |
| 747 | Phosphorylation | RRKRKERSNDEEVEV HHHHHHHCCCCCCCC | 50.12 | 24961812 | |
| 758 | Acetylation | EVEVDESKEESTNTI CCCCCCCHHHHCCCC | 64.55 | 22865919 | |
| 761 | Phosphorylation | VDESKEESTNTIEKE CCCCHHHHCCCCCHH | 28.22 | 24961812 | |
| 762 | Phosphorylation | DESKEESTNTIEKEE CCCHHHHCCCCCHHH | 39.39 | 24961812 | |
| 764 | Phosphorylation | SKEESTNTIEKEEKS CHHHHCCCCCHHHHC | 30.51 | 24961812 | |
| 770 | Acetylation | NTIEKEEKSENNAEE CCCCHHHHCCCCHHH | 65.25 | 24489116 | |
| 771 | Phosphorylation | TIEKEEKSENNAEEN CCCHHHHCCCCHHHC | 49.16 | 24961812 | |
| 790 | Acetylation | LVQGSEVKGDPLGTP EEECCEECCCCCCCH | 54.25 | 24489116 | |
| 796 | Phosphorylation | VKGDPLGTPEKVENM ECCCCCCCHHHHHHH | 35.64 | 22369663 | |
| 799 | Acetylation | DPLGTPEKVENMIEQ CCCCCHHHHHHHHHH | 56.93 | 24489116 | |
| 837 | Acetylation | EVGEESNKSSVIETN HHCCCCCCCCEEEEC | 54.08 | 24489116 | |
| 853 | Acetylation | GVQIMDPKGAVQNGY CEEEECCCCCCCCCC | 56.06 | 24489116 | |
| 888 | Acetylation | HKSAPEHKTSYWSVR CCCCCCCCCCHHHHH | 37.19 | 24489116 | |
| 897 | Phosphorylation | SYWSVRESQLFPELL CHHHHHHHHHHHHHH | 22.94 | 28889911 | |
| 917 | Acetylation | QWSLISEKLGTKSTT HHHHHHHHHCCCCHH | 45.48 | 24489116 | |
| 949 | Acetylation | LVDETDLKRDGTSSE EEEHHHHCCCCCCCH | 51.78 | 24489116 | |
| 1022 | Acetylation | FHRDTFSKISAPLTT CCCCCCCCCCCCCCC | 36.17 | 24489116 | |
| 1037 | Phosphorylation | LPPPRLPSIQFPRSE CCCCCCCCCCCCHHH | 33.35 | 28889911 | |
| 1091 | Phosphorylation | IDIGRKSTTISNLLN HHHCCHHHHHHHHHH | 31.05 | 19779198 | |
| 1094 | Phosphorylation | GRKSTTISNLLNNSD CCHHHHHHHHHHCCC | 21.23 | 28889911 | |
| 1100 | Phosphorylation | ISNLLNNSDRSMKSS HHHHHHCCCHHHHHH | 33.07 | 22369663 | |
| 1103 | Phosphorylation | LLNNSDRSMKSSFQS HHHCCCHHHHHHHHH | 35.24 | 28889911 | |
| 1106 | Phosphorylation | NSDRSMKSSFQSASR CCCHHHHHHHHHHHH | 27.95 | 28889911 | |
| 1137 | Phosphorylation | QEIKPNITTPRSSSI EECCCCCCCCCCCCC | 37.07 | 19779198 | |
| 1138 | Phosphorylation | EIKPNITTPRSSSIS ECCCCCCCCCCCCCH | 16.95 | 28889911 | |
| 1143 | Phosphorylation | ITTPRSSSISALLNP CCCCCCCCCHHHCCC | 23.08 | 19779198 | |
| 1210 | Phosphorylation | AALAAVASAPDAMSS HHHHHHHCCHHHHHH | 33.46 | 19779198 | |
| 1217 | Phosphorylation | SAPDAMSSFLSKKEN CCHHHHHHHHHHHHC | 19.68 | 19779198 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SNT1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SNT1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SNT1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-187; SER-395; THR-796;SER-1037 AND THR-1138, AND MASS SPECTROMETRY. | |
| "Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-796, AND MASSSPECTROMETRY. | |
