| UniProt ID | MUD2_YEAST | |
|---|---|---|
| UniProt AC | P36084 | |
| Protein Name | Splicing factor MUD2 | |
| Gene Name | MUD2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 527 | |
| Subcellular Localization | ||
| Protein Description | Splicing factor that contacts pre-mRNA directly and is a component of the pre-mRNA-U1 snRNP complex (commitment complex 2) that forms during early spliceosome assembly in yeast extracts.. | |
| Protein Sequence | MADEKRLEDLRSKIMESIGKSEKDVVPIENKRFNTDNAVIDTHFKRQKSDGELPKAPKSRNVSHSNNRGPSSIITMSTNRTTYEQTRAGPHRQSYRDASGRSYNRENRYSSHNTGPQWNNNPYNRQRDERRGRNERFDRRGRNGNGNYDRFNYQRKNEGSKFNGDRDKRQLQTNKYDMNYNSQNVMYPGSSFDSPAYYNMASSKANSRLVISGLSQSSDPSIVARLKDLLENFISGLQKTESNAEDFKISNFYIGEGRPDHIIVEFSSQICSTMVLACRSFFNAKLGTFDLKWRRPNDYVQQLDHLVDFCRGTVIALENLENIGEGEDYRMKELFSSLNVTNGTAKPLFYKCSSNTNNTGKESEFTKCILLSFEVVTQDILDKLKPYKWFKPNDGKISQVTSWITFQSLPNLVTQSVRVESRVLLLLNCLDPLDLKDETFITEIKETLKYSIAGADTIKICQPGVDYRLNFENLASGAGNIYIKFKTLEAAKHAMEELPGTQFNDRTVLCTYIDEDDFDMMEATQLS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 17 | Phosphorylation | LRSKIMESIGKSEKD HHHHHHHHHCCCCCC | 21.18 | 28889911 | |
| 23 | Acetylation | ESIGKSEKDVVPIEN HHHCCCCCCEEECCC | 64.01 | 25381059 | |
| 45 | Acetylation | AVIDTHFKRQKSDGE CEEEHHHHHCCCCCC | 46.44 | 24489116 | |
| 49 | Phosphorylation | THFKRQKSDGELPKA HHHHHCCCCCCCCCC | 42.37 | 17287358 | |
| 156 | Acetylation | DRFNYQRKNEGSKFN CCCCCCCCCCCCCCC | 43.77 | 25381059 | |
| 161 | Acetylation | QRKNEGSKFNGDRDK CCCCCCCCCCCCHHH | 54.42 | 25381059 | |
| 292 | Acetylation | KLGTFDLKWRRPNDY CCCEECCEECCCCHH | 40.26 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MUD2_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MUD2_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MUD2_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "Analysis of phosphorylation sites on proteins from Saccharomycescerevisiae by electron transfer dissociation (ETD) massspectrometry."; Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.; Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-49, AND MASSSPECTROMETRY. | |
