PRM6_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PRM6_YEAST
• UniProt AC: Q04705
• Protein Name: Pheromone-regulated membrane protein 6
• Gene Name: PRM6
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 352
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MESSLQKLKFQDIDINLIPTAKWTTKLQYILYTWCQSILHVAMFFSDIYTCIKLLAFNTWSNNIIQPFLEFRISKWLFSGCILCSSLILIWELVIGLRVYRKKEITSNYMNGISRLINCLFNFKKYQIFELIVLTDEKKFSKWLFFSYFEISGCLRLLFGDSPRQIINGLTLWSVLLTVSNETSSGTHSTQSLGNLDDLNGIINKIKHIAKTNYEESVILSFMLFSFIIWVILISKLILSIIIFIIFIRPRFLSSKRKVKGYELKLRKYVSKVIDENLSRTVYELGILIDDEEEGTICGDNKTQKKFDYDSPDYGDESTIPSYYCYSDVETYERVYTPIKAYFPQKYKHKYI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
147	Phosphorylation	FSKWLFFSYFEISGC HCHHHHHHHHCCHHH	22.90	27214570
148	Phosphorylation	SKWLFFSYFEISGCL CHHHHHHHHCCHHHH	10.48	27214570
235	Phosphorylation	IIWVILISKLILSII HHHHHHHHHHHHHHH	20.26	19684113
240	Phosphorylation	LISKLILSIIIFIIF HHHHHHHHHHHHHHH	12.54	19684113

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PRM6_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PRM6_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PRM6_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BAR1_YEAST	BAR1	genetic	23204190
H4_YEAST	HHF1	genetic	27708008
YPQ3_YEAST	RTC2	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.