| UniProt ID | CSF1_YEAST | |
|---|---|---|
| UniProt AC | Q12150 | |
| Protein Name | Protein CSF1 | |
| Gene Name | CSF1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 2958 | |
| Subcellular Localization |
Membrane Single-pass type II membrane protein . |
|
| Protein Description | Required for the glucose and other nutrients uptake at low temperature.. | |
| Protein Sequence | MEAISQLRGVPLTHQKDFSWVFLVDWILTVVVCLTMIFYMGRIYAYLVSFILEWLLWKRAKIKINVETLRVSLLGGRIHFKNLSVIHKDYTISVLEGSLTWKYWLLNCRKAELIENNKSSSGKKAKLPCKISVECEGLEIFIYNRTVAYDNVINLLSKDERDKFEKYLNEHSFPEPFSDGSSADKLDEDLSESAYTTNSDASIVNDRDYQETDIGKHPKLLMFLPIELKFSRGSLLLGNKFTPSVMILSYESGKGIIDVLPPKERLDLYRNKTQMEFKNFEISIKQNIGYDDAIGLKFKIDRGKVSKLWKTFVRVFQIVTKPVVPKKTKKSAGTSDDNFYHKWKGLSLYKASAGDAKASDLDDVEFDLTNHEYAKFTSILKCPKVTIAYDVDVPGVVPHGAHPTIPDIDGPDVGNNGAPPDFALDVQIHGGSICYGPWAQRQVSHLQRVLSPVVSRTAKPIKKLPPGSRRIYTLFRMNISIMEDTTWRIPTRESSKDPEFLKHYKETNEEYRPFGWMDLRFCKDTYANFNISVCPTVQGFQNNFHVHFLETEIRSSVNHDILLKSKVFDIDGDIGYPLGWNSKAIWIINMKSEQLEAFLLREHITLVADTLSDFSAGDPTPYELFRPFVYKVNWEMEGYSIYLNVNDHNIVNNPLDFNENCYLSLHGDKLSIDVTVPRESILGTYTDMSYEISTPMFRMMLNTPPWNTLNEFMKHKEVGRAYDFTIKGSYLLYSELDIDNVDTLVIECNSKSTVLHCYGFVMRYLTNVKMNYFGEFFNFVTSEEYTGVLGAREVGDVTTKSSVADLASTVDSGYQNSSLKNESEDKGPMKRSDLKRTTNETDIWFTFSVWDGALILPETIYSFDPCIALHFAELVVDFRSCNYYMDIMAVLNGTSIKRHVSKQINEVFDFIRRNNGADEQEHGLLSDLTIHGHRMYGLPPTEPTYFCQWDINLGDLCIDSDIEFIKGFFNSFYKIGFGYNDLENILLYDTETINDMTSLTVHVEKIRIGLKDPVMKSQSVISAESILFTLIDFENEKYSQRIDVKIPKLTISLNCVMGDGVDTSFLKFETKLRFTNFEQYKDIDKKRSEQRRYITIHDSPYHRCPFLLPLFYQDSDTYQNLYGAIAPSSSIPTLPLPTLPDTIDYIIEDIVGEYATLLETTNPFKNIFAETPSTMEPSRASFSEDDNDEEADPSSFKPVAFTEDRNHERDNYVVDVSYILLDVDPLLFIFAKSLLEQLYSENMVQVLDDIEIGIVKRLSNLQEGITSISNIDIHIAYLNLIWQETGEEGFELYLDRIDYQMSEKSLEKNRTNKLLEVAALAKVKTVRVTVNQKKNPDLSEDRPPALSLGIEGFEVWSSTEDRQVNSLNLTSSDITIDESQMEWLFEYCSDQGNLIQEVCTSFNSIQNTRSNSKTELISKLTAASEYYQISHDPYVITKPAFIMRLSKGHVRENRSWKIITRLRHILTYLPDDWQSNIDEVLKEKKYTSAKDAKNIFMSVFSTWRNWEFSDVARSYIYGKLFTAENEKHKQNLIKKLLKCTMGSFYLTVYGEGYEVEHNFVVADANLVVDLTPPVTSLPSNREETIEITGRVGSVKGKFSDRLLKLQDLIPLIAAVGEDDKSDPKKELSKQFKMNTVLLVDKSELQLVMDQTKLMSRTVGGRVSLLWENLKDSTSQAGSLVIFSQKSEVWLKHTSVILGEAQLRDFSVLATTEAWSHKPTILINNQCADLHFRAMSSTEQLVTAITEIRESLMMIKERIKFKPKSKKKSQFVDQKINTVLSCYFSNVSSEVMPLSPFYIRHEAKQLDIYFNKFGSNEILLSIWDTDFFMTSHQTKEQYLRFSFGDIEIKGGISREGYSLINVDISISMIKLTFSEPRRIVNSFLQDEKLASQGINLLYSLKPLFFSSNLPKKEKQAPSIMINWTLDTSITYFGVLVPVASTYFVFELHMLLLSLTNTNNGMLPEETKVTGQFSIENILFLIKERSLPIGLSKLLDFSIKVSTLQRTVDTEQSFQVESSHFRVCLSPDSLLRLMWGAHKLLDLSHYYSRRHAPNIWNTKMFTGKSDKSKEMPINFRSIHILSYKFCIGWIFQYGAGSNPGLMLGYNRLFSAYEKDFGKFTVVDAFFSVANGNTSSTFFSEGNEKDKYNRSFLPNMQISYWFKRCGELKDWFFRFHGEALDVNFVPSFMDVIESTLQSMRAFQELKKNILDVSESLRAENDNSYASTSVESASSSLAPFLDNIRSVNSNFKYDGGVFRVYTYEDIETKSEPSFEIKSPVVTINCTYKHDEDKVKPHKFRTLITVDPTHNTLYAGCAPLLMEFSESLQKMIKKHSTDEKPNFTKPSSQNVDYKRLLDQFDVAVKLTSAKQQLSLSCEPKAKVQADVGFESFLFSMATNEFDSEQPLEFSLTLEHTKASIKHIFSREVSTSFEVGFMDLTLLFTHPDVISMYGTGLVSDLSVFFNVKQLQNLYLFLDIWRFSSILHTRPVQRTVNKEIEMSSLTSTNYADAGTEIPWCFTLIFTNVSGDVDLGPSLGMISLRTQRTWLATDHYNEKRQLLHAFTDGISLTSEGRLSGLFEVANASWLSEVKWPPEKSKNTHPLVSTSLNIDDIAVKAAFDYHMFLIGTISNIHFHLHNEKDAKGVLPDLLQVSFSSDEIILSSTALVVANILDIYNTIVRMRQDNKISYMETLRDSNPGESRQPILYKDILRSLKLLRTDLSVNISSSKVQISPISLFDVEVLVIRIDKVSIRSETHSGKKLKTDLQLQVLDVSAALSTSKEELDEEVGASIAIDDYMHYASKIVGGTIIDIPKLAVHMTTLQEEKTNNLEYLFACSFSDKISVRWNLGPVDFIKEMWTTHVKALAVRRSQVANISFGQTEEELEESIKKEEAASKFNYIALEEPQIEVPQIRDLGDATPPMEWFGVNRKKFPKFTHQTAVIPVQKLVYLAEKQYVKILDDTH | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 82 | N-linked_Glycosylation | GGRIHFKNLSVIHKD CCEEEEECEEEEECC | 36.28 | - | |
| 117 | N-linked_Glycosylation | KAELIENNKSSSGKK HHHHHHCCCCCCCCC | 32.56 | - | |
| 144 | N-linked_Glycosylation | GLEIFIYNRTVAYDN CEEEEEEECCCCHHH | 28.47 | - | |
| 271 | N-linked_Glycosylation | ERLDLYRNKTQMEFK HHHHHHCCCCHHHHC | 37.86 | - | |
| 349 | Phosphorylation | KWKGLSLYKASAGDA HHHCCEEEECCCCCC | 10.92 | 28889911 | |
| 359 | Phosphorylation | SAGDAKASDLDDVEF CCCCCCCCCCCCCEE | 37.69 | 20377248 | |
| 473 | Phosphorylation | PGSRRIYTLFRMNIS CCCCEEEEEEEEEEE | 19.63 | 28889911 | |
| 478 | N-linked_Glycosylation | IYTLFRMNISIMEDT EEEEEEEEEEECCCC | 22.16 | - | |
| 530 | N-linked_Glycosylation | KDTYANFNISVCPTV CCCCCCCEEEECCCC | 25.98 | - | |
| 576 | Phosphorylation | DIDGDIGYPLGWNSK ECCCCCCCCCCCCCE | 8.80 | 19779198 | |
| 708 | Phosphorylation | LNTPPWNTLNEFMKH HCCCCCCHHHHHHHC | 27.39 | 28889911 | |
| 730 | Phosphorylation | DFTIKGSYLLYSELD EEEECCEEEEEEEEC | 14.92 | 28132839 | |
| 733 | Phosphorylation | IKGSYLLYSELDIDN ECCEEEEEEEECCCC | 9.48 | 28132839 | |
| 799 | Phosphorylation | REVGDVTTKSSVADL EEECCCCCCCHHHHH | 28.86 | 28889911 | |
| 808 | Phosphorylation | SSVADLASTVDSGYQ CHHHHHHHHHCCCCC | 35.94 | 28132839 | |
| 809 | Phosphorylation | SVADLASTVDSGYQN HHHHHHHHHCCCCCC | 23.79 | 28132839 | |
| 812 | Phosphorylation | DLASTVDSGYQNSSL HHHHHHCCCCCCCCC | 34.76 | 28132839 | |
| 816 | N-linked_Glycosylation | TVDSGYQNSSLKNES HHCCCCCCCCCCCCC | 25.69 | - | |
| 818 | Phosphorylation | DSGYQNSSLKNESED CCCCCCCCCCCCCCC | 51.41 | 28889911 | |
| 821 | N-linked_Glycosylation | YQNSSLKNESEDKGP CCCCCCCCCCCCCCC | 64.42 | - | |
| 839 | N-linked_Glycosylation | SDLKRTTNETDIWFT HHHCCCCCCCCEEEE | 49.94 | - | |
| 880 | Phosphorylation | ELVVDFRSCNYYMDI HHHEEHHHCCHHHHH | 13.50 | 30377154 | |
| 883 | Phosphorylation | VDFRSCNYYMDIMAV EEHHHCCHHHHHHHH | 12.42 | 30377154 | |
| 884 | Phosphorylation | DFRSCNYYMDIMAVL EHHHCCHHHHHHHHH | 3.70 | 30377154 | |
| 892 | N-linked_Glycosylation | MDIMAVLNGTSIKRH HHHHHHHCCHHHHHH | 45.13 | - | |
| 894 | Phosphorylation | IMAVLNGTSIKRHVS HHHHHCCHHHHHHHH | 26.63 | 30377154 | |
| 895 | Phosphorylation | MAVLNGTSIKRHVSK HHHHCCHHHHHHHHH | 27.75 | 30377154 | |
| 1029 | Phosphorylation | SAESILFTLIDFENE CHHHHHHHHHHCCCC | 21.25 | 28747907 | |
| 1181 | Phosphorylation | TMEPSRASFSEDDND CCCCCCCCCCCCCCC | 28.35 | 28889911 | |
| 1183 | Phosphorylation | EPSRASFSEDDNDEE CCCCCCCCCCCCCCC | 37.31 | 28889911 | |
| 1304 | Ubiquitination | IDYQMSEKSLEKNRT HCHHCCHHHHHHCHH | 53.70 | 23749301 | |
| 1309 | N-linked_Glycosylation | SEKSLEKNRTNKLLE CHHHHHHCHHCHHHH | 46.78 | - | |
| 1368 | N-linked_Glycosylation | DRQVNSLNLTSSDIT CCCCCEEECCCCCEE | 40.88 | - | |
| 1453 | N-linked_Glycosylation | SKGHVRENRSWKIIT CCCCCCCCCHHHHHH | 32.49 | - | |
| 1486 | Phosphorylation | EVLKEKKYTSAKDAK HHHHHCCCCCHHHHH | 19.59 | 27017623 | |
| 1683 | Phosphorylation | AGSLVIFSQKSEVWL CCCEEEEECCCCEEE | 26.10 | 27017623 | |
| 1785 | N-linked_Glycosylation | VLSCYFSNVSSEVMP HHHHHHCCCCCCCCC | 28.00 | - | |
| 1841 | Phosphorylation | KEQYLRFSFGDIEIK HHHHCCEEECCEEEE | 23.14 | 28889911 | |
| 1852 | Phosphorylation | IEIKGGISREGYSLI EEEECCCCCCCEEEE | 27.79 | 27017623 | |
| 1866 | Phosphorylation | INVDISISMIKLTFS EEEEEEEEEEEEECC | 13.99 | 27017623 | |
| 1921 | N-linked_Glycosylation | QAPSIMINWTLDTSI CCCCEEEEEECCCCE | 14.32 | - | |
| 2130 | N-linked_Glycosylation | FFSVANGNTSSTFFS EEEECCCCCCCCCCC | 36.27 | - | |
| 2132 | Phosphorylation | SVANGNTSSTFFSEG EECCCCCCCCCCCCC | 31.23 | 27017623 | |
| 2133 | Phosphorylation | VANGNTSSTFFSEGN ECCCCCCCCCCCCCC | 27.48 | 27017623 | |
| 2134 | Phosphorylation | ANGNTSSTFFSEGNE CCCCCCCCCCCCCCC | 28.59 | 27017623 | |
| 2146 | N-linked_Glycosylation | GNEKDKYNRSFLPNM CCCCCCCCHHCCCCC | 38.57 | - | |
| 2184 | Phosphorylation | LDVNFVPSFMDVIES CCCCCCHHHHHHHHH | 28.09 | 28152593 | |
| 2280 | N-linked_Glycosylation | KSPVVTINCTYKHDE CCCEEEEEEEEECCC | 11.60 | - | |
| 2337 | N-linked_Glycosylation | HSTDEKPNFTKPSSQ CCCCCCCCCCCCCCC | 69.18 | - | |
| 2398 | Phosphorylation | MATNEFDSEQPLEFS HHCCCCCCCCCEEEE | 43.37 | 19779198 | |
| 2411 | Phosphorylation | FSLTLEHTKASIKHI EEEEEECHHHHHHHH | 20.94 | 19779198 | |
| 2414 | Phosphorylation | TLEHTKASIKHIFSR EEECHHHHHHHHHCC | 33.45 | 19779198 | |
| 2425 | Phosphorylation | IFSREVSTSFEVGFM HHCCCCCCCEEEECC | 42.48 | 27017623 | |
| 2426 | Phosphorylation | FSREVSTSFEVGFMD HCCCCCCCEEEECCE | 16.35 | 27017623 | |
| 2439 | Phosphorylation | MDLTLLFTHPDVISM CEEEEEECCHHHHHH | 32.25 | 27017623 | |
| 2447 | Phosphorylation | HPDVISMYGTGLVSD CHHHHHHHCCCCCCC | 12.54 | 27017623 | |
| 2449 | Phosphorylation | DVISMYGTGLVSDLS HHHHHHCCCCCCCHH | 15.17 | 27017623 | |
| 2520 | N-linked_Glycosylation | CFTLIFTNVSGDVDL EEEEEEECCCCCCCC | 18.40 | - | |
| 2578 | N-linked_Glycosylation | SGLFEVANASWLSEV CHHHEECCCHHHHCC | 39.42 | - | |
| 2719 | N-linked_Glycosylation | LRTDLSVNISSSKVQ HCCCCEEECCCCCEE | 25.67 | - | |
| 2759 | Phosphorylation | HSGKKLKTDLQLQVL CCCCCCCCCEEHHHH | 52.99 | 22890988 | |
| 2769 | Phosphorylation | QLQVLDVSAALSTSK EHHHHCHHHHHCCCH | 13.90 | 22890988 | |
| 2773 | Phosphorylation | LDVSAALSTSKEELD HCHHHHHCCCHHHHH | 26.38 | 22890988 | |
| 2774 | Phosphorylation | DVSAALSTSKEELDE CHHHHHCCCHHHHHH | 44.67 | 22890988 | |
| 2775 | Phosphorylation | VSAALSTSKEELDEE HHHHHCCCHHHHHHH | 34.39 | 22890988 | |
| 2786 | Phosphorylation | LDEEVGASIAIDDYM HHHHHCCCHHHHHHH | 13.46 | 28747907 | |
| 2795 | Phosphorylation | AIDDYMHYASKIVGG HHHHHHHHHHHHCCC | 8.95 | 28747907 | |
| 2797 | Phosphorylation | DDYMHYASKIVGGTI HHHHHHHHHHCCCEE | 18.75 | 28747907 | |
| 2815 | Phosphorylation | PKLAVHMTTLQEEKT HHHHEEHHCCCCHHC | 14.96 | 28747907 | |
| 2816 | Phosphorylation | KLAVHMTTLQEEKTN HHHEEHHCCCCHHCC | 20.90 | 28747907 | |
| 2822 | Phosphorylation | TTLQEEKTNNLEYLF HCCCCHHCCCCEEEE | 32.39 | 28747907 | |
| 2827 | Phosphorylation | EKTNNLEYLFACSFS HHCCCCEEEEEEECC | 15.41 | 28747907 | |
| 2832 | Phosphorylation | LEYLFACSFSDKISV CEEEEEEECCCCEEE | 25.10 | 28747907 | |
| 2834 | Phosphorylation | YLFACSFSDKISVRW EEEEEECCCCEEEEE | 23.00 | 28747907 | |
| 2854 | Phosphorylation | DFIKEMWTTHVKALA HHHHHHHHHHHHHHH | 13.00 | 27017623 | |
| 2869 | N-linked_Glycosylation | VRRSQVANISFGQTE HHHHHHCCEECCCCH | 31.42 | - | |
| 2914 | Phosphorylation | IRDLGDATPPMEWFG CCCCCCCCCCCCCCC | 32.44 | 27017623 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CSF1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CSF1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CSF1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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