| UniProt ID | SKT5_YEAST | |
|---|---|---|
| UniProt AC | P34226 | |
| Protein Name | Protein SKT5 | |
| Gene Name | SKT5 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 696 | |
| Subcellular Localization |
Cell membrane Lipid-anchor Cytoplasmic side . |
|
| Protein Description | Possible role in protoplast regeneration and killer toxin of K.lactis (PGKL) resistance.. | |
| Protein Sequence | MASSPQVHPYKKHLMQSQHINFDNRGLQFQNSSLKVGQDFSDNKENRENRDNEDFSTADLPKRSANQPLINEHLRAASVPLLSNDIGNSQEEDFVPVPPPQLHLNNSNNTSLSSLGSTPTNSPSPGALRQTNSSTSLTKEQIKKRTRSVDLSHMYLLNGSSDTQLTATNESVADLSHQMISRYLGGKNNTSLVPRLKTIEMYRQNVKKSKDPEVLFQYAQYMLQTALTIESSNALVQDSDKEGNVSQSDLKLQFLKEAQSYLKKLSIKGYSDAQYLLADGYSSGAFGKIENKEAFVLFQAAAKHGHIESAYRASHCLEEGLGTTRDSRKSVNFLKFAASRNHPSAMYKLGLYSFYGRMGLPTDVNTKLNGVKWLSRAAARANELTAAAPYELAKIYHEGFLDVVIPDEKYAMELYIQAASLGHVPSATLLAQIYETGNDTVGQDTSLSVHYYTQAALKGDSVAMLGLCAWYLLGAEPAFEKDENEAFQWALRAANAGLPKAQFTLGYFYEHGKGCDRNMEYAWKWYEKAAGNEDKRAINKLRSRDGGLASIGKKQHKKNKSISTLNLFSTVDSQTSNVGSNSRVSSKSETFFTGNPKRDREPQGLQINMNSNTNRNGIKTGSDTSIRKSSSSAKGMSREVAEQSMAAKQEVSLSNMGSSNMIRKDFPAVKTESKKPTSLKNKKDKQGKKKKDCVIM | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MASSPQVHPY -----CCCCCCCCCC | 41.05 | 22369663 | |
| 4 | Phosphorylation | ----MASSPQVHPYK ----CCCCCCCCCCH | 15.15 | 22369663 | |
| 10 | Phosphorylation | SSPQVHPYKKHLMQS CCCCCCCCHHHHHHC | 20.14 | 22369663 | |
| 32 | Phosphorylation | RGLQFQNSSLKVGQD CCCCCCCCCCCCCCC | 26.68 | 22369663 | |
| 33 | Phosphorylation | GLQFQNSSLKVGQDF CCCCCCCCCCCCCCC | 39.50 | 22369663 | |
| 41 | Phosphorylation | LKVGQDFSDNKENRE CCCCCCCCCCHHHCC | 48.87 | 19779198 | |
| 44 | Ubiquitination | GQDFSDNKENRENRD CCCCCCCHHHCCCCC | 62.45 | 23749301 | |
| 56 | Phosphorylation | NRDNEDFSTADLPKR CCCCCCCCHHHCCCC | 34.70 | 28889911 | |
| 57 | Phosphorylation | RDNEDFSTADLPKRS CCCCCCCHHHCCCCC | 24.96 | 21551504 | |
| 107 | Phosphorylation | PQLHLNNSNNTSLSS CCEEECCCCCCCHHH | 30.31 | 28889911 | |
| 111 | Phosphorylation | LNNSNNTSLSSLGST ECCCCCCCHHHCCCC | 28.51 | 27738172 | |
| 113 | Phosphorylation | NSNNTSLSSLGSTPT CCCCCCHHHCCCCCC | 24.23 | 27738172 | |
| 131 | Phosphorylation | SPGALRQTNSSTSLT CCCCCCCCCCCCCCC | 30.54 | 19684113 | |
| 133 | Phosphorylation | GALRQTNSSTSLTKE CCCCCCCCCCCCCHH | 38.08 | 22369663 | |
| 134 | Phosphorylation | ALRQTNSSTSLTKEQ CCCCCCCCCCCCHHH | 24.88 | 22369663 | |
| 135 | Phosphorylation | LRQTNSSTSLTKEQI CCCCCCCCCCCHHHH | 27.81 | 22369663 | |
| 136 | Phosphorylation | RQTNSSTSLTKEQIK CCCCCCCCCCHHHHH | 35.67 | 22369663 | |
| 138 | Phosphorylation | TNSSTSLTKEQIKKR CCCCCCCCHHHHHHH | 32.10 | 29734811 | |
| 139 | Ubiquitination | NSSTSLTKEQIKKRT CCCCCCCHHHHHHHC | 53.57 | 23749301 | |
| 146 | Phosphorylation | KEQIKKRTRSVDLSH HHHHHHHCCCCCCHH | 35.85 | 19779198 | |
| 148 | Phosphorylation | QIKKRTRSVDLSHMY HHHHHCCCCCCHHHE | 21.26 | 28889911 | |
| 152 | Phosphorylation | RTRSVDLSHMYLLNG HCCCCCCHHHEECCC | 11.18 | 19779198 | |
| 155 | Phosphorylation | SVDLSHMYLLNGSSD CCCCHHHEECCCCCC | 11.56 | 28889911 | |
| 160 | Phosphorylation | HMYLLNGSSDTQLTA HHEECCCCCCCCCEE | 24.78 | 21440633 | |
| 161 | Phosphorylation | MYLLNGSSDTQLTAT HEECCCCCCCCCEEC | 46.18 | 22369663 | |
| 163 | Phosphorylation | LLNGSSDTQLTATNE ECCCCCCCCCEECCC | 27.68 | 22369663 | |
| 166 | Phosphorylation | GSSDTQLTATNESVA CCCCCCCEECCCHHH | 22.94 | 22369663 | |
| 168 | Phosphorylation | SDTQLTATNESVADL CCCCCEECCCHHHHH | 33.99 | 22369663 | |
| 171 | Phosphorylation | QLTATNESVADLSHQ CCEECCCHHHHHHHH | 25.36 | 28889911 | |
| 231 | Phosphorylation | QTALTIESSNALVQD HHHHHHHCCCCCCCC | 25.66 | 21551504 | |
| 239 | Phosphorylation | SNALVQDSDKEGNVS CCCCCCCCCCCCCCC | 33.23 | 21551504 | |
| 550 | Phosphorylation | SRDGGLASIGKKQHK HCCCCCCCCCCHHHC | 36.60 | 28152593 | |
| 561 | Phosphorylation | KQHKKNKSISTLNLF HHHCCCCCCCCHHCH | 31.03 | 17330950 | |
| 563 | Phosphorylation | HKKNKSISTLNLFST HCCCCCCCCHHCHHC | 33.65 | 17330950 | |
| 564 | Phosphorylation | KKNKSISTLNLFSTV CCCCCCCCHHCHHCC | 20.28 | 17330950 | |
| 569 | Phosphorylation | ISTLNLFSTVDSQTS CCCHHCHHCCCCCCC | 30.59 | 19779198 | |
| 570 | Phosphorylation | STLNLFSTVDSQTSN CCHHCHHCCCCCCCC | 22.46 | 19779198 | |
| 573 | Phosphorylation | NLFSTVDSQTSNVGS HCHHCCCCCCCCCCC | 30.90 | 19779198 | |
| 575 | Phosphorylation | FSTVDSQTSNVGSNS HHCCCCCCCCCCCCC | 26.65 | 19779198 | |
| 585 | Phosphorylation | VGSNSRVSSKSETFF CCCCCCCCCCCCCCC | 30.82 | 23749301 | |
| 586 | Phosphorylation | GSNSRVSSKSETFFT CCCCCCCCCCCCCCC | 37.03 | 23749301 | |
| 588 | Phosphorylation | NSRVSSKSETFFTGN CCCCCCCCCCCCCCC | 43.76 | 22369663 | |
| 590 | Phosphorylation | RVSSKSETFFTGNPK CCCCCCCCCCCCCCC | 31.01 | 22369663 | |
| 620 | Phosphorylation | TNRNGIKTGSDTSIR CCCCCCCCCCCCCCC | 39.74 | 19823750 | |
| 622 | Phosphorylation | RNGIKTGSDTSIRKS CCCCCCCCCCCCCCC | 42.84 | 25752575 | |
| 624 | Phosphorylation | GIKTGSDTSIRKSSS CCCCCCCCCCCCCCC | 27.96 | 17563356 | |
| 625 | Phosphorylation | IKTGSDTSIRKSSSS CCCCCCCCCCCCCCC | 25.95 | 17563356 | |
| 634 | Acetylation | RKSSSSAKGMSREVA CCCCCCCCCCCHHHH | 58.03 | 23572591 | |
| 637 | Phosphorylation | SSSAKGMSREVAEQS CCCCCCCCHHHHHHH | 33.68 | 21551504 | |
| 644 | Phosphorylation | SREVAEQSMAAKQEV CHHHHHHHHHHHHHH | 11.24 | 21551504 | |
| 652 | Phosphorylation | MAAKQEVSLSNMGSS HHHHHHHCHHCCCCC | 25.90 | 28889911 | |
| 654 | Phosphorylation | AKQEVSLSNMGSSNM HHHHHCHHCCCCCCC | 19.77 | 28889911 | |
| 658 | Phosphorylation | VSLSNMGSSNMIRKD HCHHCCCCCCCCCCC | 14.05 | 23749301 | |
| 659 | Phosphorylation | SLSNMGSSNMIRKDF CHHCCCCCCCCCCCC | 25.37 | 27017623 | |
| 664 | Ubiquitination | GSSNMIRKDFPAVKT CCCCCCCCCCCCCCC | 53.44 | 23749301 | |
| 678 | Phosphorylation | TESKKPTSLKNKKDK CCCCCCCCCCCCCCC | 45.96 | 21551504 | |
| 693 | Methylation | QGKKKKDCVIM---- CCCCCCCCEEC---- | 2.83 | 17142567 | |
| 693 | Farnesylation | QGKKKKDCVIM---- CCCCCCCCEEC---- | 2.83 | 17142567 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SKT5_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SKT5_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SKT5_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-107; SER-136; SER-148;SER-171 AND SER-588, AND MASS SPECTROMETRY. | |
| "Analysis of phosphorylation sites on proteins from Saccharomycescerevisiae by electron transfer dissociation (ETD) massspectrometry."; Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.; Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-32, AND MASSSPECTROMETRY. | |
| "Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae."; Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.; J. Proteome Res. 6:1190-1197(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-561, AND MASSSPECTROMETRY. | |
| "Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-624, AND MASSSPECTROMETRY. | |
