MEP1_YEAST - dbPTM
MEP1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MEP1_YEAST
UniProt AC P40260
Protein Name Ammonium transporter MEP1
Gene Name MEP1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 492
Subcellular Localization Membrane
Multi-pass membrane protein.
Protein Description Transporter for ammonium (both charged and uncharged NH3 and NH4) to use as a nitrogen source. Can also transport methylamine. The affinity of MEP1 is about twenty times lower than that of MEP2. MEP3 has the lowest affinity..
Protein Sequence MESRTTGPLTTETYDGPTVAFMILGAALVFFMVPGLGFLYSGLARRKSALALIWVVLMATLVGILQWYFWGYSLAFSKSAPNNKFIGNLDSFGFRNVYGKKFDEDAYPELAYATFQMMFSCVNLSIIAGATAERGRLLPHMVFLFILATIGYCPVTYWIWSPGGWAYQWGVLDWAGGGNIEILSAVSGFVYSWFLGKRNEKLLINFRPHNVSLVTLGTSILWFGWLLFNSASSLSPNLRSVYAFMNTCLSAITGGMTWCLLDYRSEKKWSTVGLCSGIISGLVAATPSSGCITLYGSLIQGIVAGVVCNFATKLKYYAKVDDAMDILAEHGVAGVIGLIFNALFGADWVIGMDGTTEHEGGWVTHNYKQMYKQIAYIAASIGYTAAVTAIICFVLGYIPGMRLRISEEAEEAGMDEDQIGEFAYDYVEVRRDYYLWGVDEDSQRSDVNHRVNNAHLAAERSSSGTNSSSDGNGEMIQSEKILPIHQEDPANR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
442PhosphorylationLWGVDEDSQRSDVNH
EECCCCCCCCHHHCH		25.9927214570
445PhosphorylationVDEDSQRSDVNHRVN
CCCCCCCHHHCHHHH		37.9728747907
468PhosphorylationSSSGTNSSSDGNGEM
CCCCCCCCCCCCCCE		34.2228889911
480UbiquitinationGEMIQSEKILPIHQE
CCEECCEEEEECCCC		55.5823749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MEP1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MEP1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MEP1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CDC6_YEASTCDC6genetic
9832522
DOT6_YEASTDOT6genetic
9832522
HMS1_YEASTHMS1genetic
9832522
HMS2_YEASTHMS2genetic
9832522
MGA1_YEASTMGA1genetic
9832522
MSN5_YEASTMSN5genetic
9832522
MSS11_YEASTMSS11genetic
9832522
PHD1_YEASTPHD1genetic
9832522
MSN1_YEASTMSN1genetic
9832522
SKN7_YEASTSKN7genetic
9832522
TEC1_YEASTTEC1genetic
9832522
MEP2_YEASTMEP2genetic
9234685
MEP2_YEASTMEP2genetic
9482721
GST1_YEASTGTT1physical
11283351
MSS1_YEASTMSS1genetic
9832522
MEP3_YEASTMEP3genetic
9832522
SSD1_YEASTSSD1genetic
9832522
DAL80_YEASTDAL80genetic
9832522
URE2_YEASTURE2genetic
9832522
SFK1_YEASTSFK1physical
18467557
MEP3_YEASTMEP3physical
18467557
TCB3_YEASTTCB3physical
18467557
GST1_YEASTGTT1physical
18719252
MEP2_YEASTMEP2genetic
16941010
MEP3_YEASTMEP3genetic
16941010
METC_YEASTIRC7genetic
21623372
DCOR_YEASTSPE1genetic
21623372
QCR2_YEASTQCR2genetic
21623372
CY1_YEASTCYT1genetic
21623372
TPS2_YEASTTPS2genetic
21623372
ATPF_YEASTATP4genetic
21623372
ELO2_YEASTELO2genetic
21623372
ATP14_YEASTATP14genetic
21623372
KCS1_YEASTKCS1genetic
21623372
ATPO_YEASTATP5genetic
21623372
QCR8_YEASTQCR8genetic
21623372
ADK_YEASTADO1genetic
21623372
APA2_YEASTAPA2genetic
21623372
PHSG_YEASTGPH1genetic
21623372
6PGD1_YEASTGND1genetic
21623372
RRT12_YEASTRRT12genetic
27708008
IZH2_YEASTIZH2genetic
27708008
HSP7F_YEASTSSE1genetic
27708008
YAD7_YEASTYAL037Wgenetic
27708008
FUI1_YEASTFUI1genetic
27708008
TOD6_YEASTTOD6genetic
27708008
AVT5_YEASTAVT5genetic
27708008
ECM33_YEASTECM33genetic
27708008
DTR1_YEASTDTR1genetic
27708008
HPC2_YEASTHPC2genetic
27708008
TAH1_YEASTTAH1genetic
27708008
ACK1_YEASTACK1genetic
27708008
RPA14_YEASTRPA14genetic
27708008
MNN10_YEASTMNN10genetic
27708008
MSH4_YEASTMSH4genetic
27708008
WWM1_YEASTWWM1genetic
27708008
FSH1_YEASTFSH1genetic
27708008
HTD2_YEASTHTD2genetic
27708008
LRP1_YEASTLRP1genetic
27708008
TAX4_YEASTTAX4genetic
27708008
ELM1_YEASTELM1genetic
27708008
MDM35_YEASTMDM35genetic
27708008
FABG_YEASTOAR1genetic
27708008
DOA1_YEASTDOA1genetic
27708008
DID2_YEASTDID2genetic
27708008
RS21A_YEASTRPS21Agenetic
27708008
PSR1_YEASTPSR1genetic
27708008
RFU1_YEASTRFU1genetic
27708008
UPS1_YEASTUPS1genetic
27708008
CHS5_YEASTCHS5genetic
27708008
FKS1_YEASTFKS1genetic
27708008
YL346_YEASTYLR346Cgenetic
27708008
MTND_YEASTADI1genetic
27708008
FUS2_YEASTFUS2genetic
27708008
YNO0_YEASTYNL140Cgenetic
27708008
PFD4_YEASTGIM3genetic
27708008
COQ2_YEASTCOQ2genetic
27708008
ATG34_YEASTATG34genetic
27708008
EXO1_YEASTEXO1genetic
27708008
FABD_YEASTMCT1genetic
27708008
PCL8_YEASTPCL8genetic
27708008
FUMH_YEASTFUM1genetic
27708008
SPEE_YEASTSPE3genetic
27708008
MEP2_YEASTMEP2genetic
26172854
MEP3_YEASTMEP3genetic
26172854
PAR32_YEASTPAR32physical
26172854
CR3L1_HUMANCREB3L1physical
27107014
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MEP1_YEAST

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Related Literatures of Post-Translational Modification

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