| UniProt ID | RRT12_YEAST | |
|---|---|---|
| UniProt AC | P25381 | |
| Protein Name | Subtilase-type proteinase RRT12 | |
| Gene Name | RRT12 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 491 | |
| Subcellular Localization | Spore wall . | |
| Protein Description | Subtilisin-related protease involved in the formation of a protective dityrosine layer required for spore wall assembly. Identified in a screen for mutants with increased levels of rDNA transcription.. | |
| Protein Sequence | MKPQCILISLLVNLAYAEEYLVRFKNPTAFQQFTSNSNRSWRQFIDNKIEKKFSIGSFRGVTMNLSKNLVNKLKKSPLVADIVPNFRFEAFEGDSVNSAESSYTFNATAKYSYEDVEEEQNITYQPDAPRHLARISRHYQLPFDVGDKDRYKSWFNYYYEHDYQGQDVNAYIMDTGIFADHPEFEDRVIQGIDLTKEGFGDQNGHGTHVAGLVGSKTYGAAKRVNLVEVKVLGKDGSGEASNVLSGLEFIVEHCTKVSRPQGKKCVANLSLGSFRSPIINMAVEGAIEEGIVFVAAAGNFNLDAYWASPASAENVITVGAFDDHIDTIAKFSNWGPCVNIFAPGVEIESLSHLNYNDTLILSGTSMSTPIVTGVAAILLSKGIEPEMIAQEIEYLSTRNVFHRRTLFFKPSTPNQILYNGVDKLDDPYDDETFPRLNIEAIAKELEEYNATLQTPMSENLQSGSKLWGWNNDVTLPLGEIRLKRRDFMKNL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 38 | N-linked_Glycosylation | QQFTSNSNRSWRQFI HHHHCCCCHHHHHHH | 46.38 | - | |
| 64 | N-linked_Glycosylation | SFRGVTMNLSKNLVN CHHHHCCCCCHHHHH | 31.62 | - | |
| 106 | N-linked_Glycosylation | AESSYTFNATAKYSY CCCEEEEEEEEEEEC | 28.69 | - | |
| 121 | N-linked_Glycosylation | EDVEEEQNITYQPDA CCCHHHHCCCCCCCC | 31.67 | - | |
| 268 | N-linked_Glycosylation | QGKKCVANLSLGSFR CCCCEEEEECCCCCC | 15.12 | - | |
| 356 | N-linked_Glycosylation | SLSHLNYNDTLILSG ECCCCCCCCEEEEEC | 34.42 | - | |
| 449 | N-linked_Glycosylation | AKELEEYNATLQTPM HHHHHHHHCCCCCCC | 29.72 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RRT12_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RRT12_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RRT12_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PRP6_YEAST | PRP6 | genetic | 27708008 | |
| CDK1_YEAST | CDC28 | genetic | 27708008 | |
| APC11_YEAST | APC11 | genetic | 27708008 | |
| GNA1_YEAST | GNA1 | genetic | 27708008 | |
| PRS8_YEAST | RPT6 | genetic | 27708008 | |
| RPN1_YEAST | RPN1 | genetic | 27708008 | |
| BET1_YEAST | BET1 | genetic | 27708008 | |
| TIM44_YEAST | TIM44 | genetic | 27708008 | |
| PAN1_YEAST | PAN1 | genetic | 27708008 | |
| PRI1_YEAST | PRI1 | genetic | 27708008 | |
| DSN1_YEAST | DSN1 | genetic | 27708008 | |
| STS1_YEAST | STS1 | genetic | 27708008 | |
| MCM1_YEAST | MCM1 | genetic | 27708008 | |
| PRS10_YEAST | RPT4 | genetic | 27708008 | |
| BUR1_YEAST | SGV1 | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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