dbPTM

PHD1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PHD1_YEAST
UniProt AC	P36093
Protein Name	Putative transcription factor PHD1
Gene Name	PHD1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	366
Subcellular Localization	Nucleus.
Protein Description	Putative transcription factor that functions in pseudohyphal growth..
Protein Sequence	MYHVPEMRLHYPLVNTQSNAAITPTRSYDNTLPSFNELSHQSTINLPFVQRETPNAYANVAQLATSPTQAKSGYYCRYYAVPFPTYPQQPQSPYQQAVLPYATIPNSNFQPSSFPVMAVMPPEVQFDGSFLNTLHPHTELPPIIQNTNDTSVARPNNLKSIAAASPTVTATTRTPGVSSTSVLKPRVITTMWEDENTICYQVEANGISVVRRADNNMINGTKLLNVTKMTRGRRDGILRSEKVREVVKIGSMHLKGVWIPFERAYILAQREQILDHLYPLFVKDIESIVDARKPSNKASLTPKSSPAPIKQEPSDNKHEIATEIKPKSIDALSNGASTQGAGELPHLKINHIDTEAQTSRAKNELS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	TQSNAAITPTRSYDN CCCCCCCCCCCCCCC	17.55	28889911
66	Phosphorylation	NVAQLATSPTQAKSG CHHHHHCCCCHHCCC	21.97	28132839
165	Phosphorylation	LKSIAAASPTVTATT HHHHHHCCCEEEEEE	19.17	22369663
283	Ubiquitination	HLYPLFVKDIESIVD HHHHHHHHHHHHHHH	45.73	17644757
295	Phosphorylation	IVDARKPSNKASLTP HHHCCCCCCCCCCCC	54.73	23749301
299	Phosphorylation	RKPSNKASLTPKSSP CCCCCCCCCCCCCCC	34.09	21440633
301	Phosphorylation	PSNKASLTPKSSPAP CCCCCCCCCCCCCCC	26.61	20377248
304	Phosphorylation	KASLTPKSSPAPIKQ CCCCCCCCCCCCCCC	42.64	20377248
305	Phosphorylation	ASLTPKSSPAPIKQE CCCCCCCCCCCCCCC	31.07	21551504
333	Phosphorylation	PKSIDALSNGASTQG CCHHHHHHCCCCCCC	34.63	27017623
337	Phosphorylation	DALSNGASTQGAGEL HHHHCCCCCCCCCCC	23.74	27017623
354	Phosphorylation	LKINHIDTEAQTSRA EEEEECCHHHHHHHH	32.39	27017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PHD1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PHD1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PHD1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SMT3_YEAST	SMT3	physical	11283351
FLO8_YEAST	FLO8	genetic	15466424
MSS11_YEAST	MSS11	genetic	15466424
SMT3_YEAST	SMT3	physical	18719252
STB5_YEAST	STB5	genetic	20959818
AATC_YEAST	AAT2	genetic	20959818
RPA34_YEAST	RPA34	genetic	20959818
HAP5_YEAST	HAP5	genetic	20959818
STB1_YEAST	STB1	genetic	20959818
HAL5_YEAST	HAL5	genetic	21127252
HAL4_YEAST	SAT4	genetic	21127252
PP4C_YEAST	PPH3	genetic	21127252
ASK10_YEAST	ASK10	genetic	27708008
INO4_YEAST	INO4	genetic	27708008
PRP6_YEAST	PRP6	genetic	27708008
APC11_YEAST	APC11	genetic	27708008
SWC4_YEAST	SWC4	genetic	27708008
SEC22_YEAST	SEC22	genetic	27708008
LCB1_YEAST	LCB1	genetic	27708008
NUF2_YEAST	NUF2	genetic	27708008
SEC62_YEAST	SEC62	genetic	27708008
ASA1_YEAST	ASA1	genetic	27708008
PTH2_YEAST	PTH2	genetic	27708008
CHK1_YEAST	CHK1	genetic	27708008
APE3_YEAST	APE3	genetic	27708008
LDB17_YEAST	LDB17	genetic	27708008
NPY1_YEAST	NPY1	genetic	27708008
SCY1_YEAST	SCY1	genetic	27708008
MED5_YEAST	NUT1	genetic	27708008
VPS53_YEAST	VPS53	genetic	27708008
PTK2_YEAST	PTK2	genetic	27708008
VPS9_YEAST	VPS9	genetic	27708008
SOK2_YEAST	SOK2	genetic	27708008
SIN3_YEAST	SIN3	genetic	27708008
NEW1_YEAST	NEW1	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PHD1_YEAST

Related Literatures of Post-Translational Modification