dbPTM

NPY1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	NPY1_YEAST
UniProt AC	P53164
Protein Name	NADH pyrophosphatase
Gene Name	NPY1
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	384
Subcellular Localization
Protein Description
Protein Sequence	MSTAVTFFGQHVLNRVSFLRCSKEFIKKSLNHDSTVFIPFIEGEALISPENGDLVQLSNSVKSYKNILSAIVPLYTTLLNTTRSRSDESGINVTFLGLLEGTDSAFNFEWSNISYKGTPYFGLDIRVTESTLFKKVDFEPIFSYPKVTRDHIFKQTNEDASLYSQGKMYLDWLAKYKFCPGCGSPLFPVEAGTKLQCSNENRNVYCNVRDARINNVCFPRTDPTVIIALTNSDYSKCCLARSKKRYGDFVLYSTIAGFMEPSETIEEACIREIWEETGISCKNIDIVRSQPWPYPCSLMIGCLGIVQFNSKNEVINLNHDDELLDAQWFDTTEIIQALDKYAGGYRVPFKNDINLPGSTTIAFQLINHVCENYKNLRKTSSSHL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSTAVTFFG ------CCCHHHHHH	25.69	28889911
3	Phosphorylation	-----MSTAVTFFGQ -----CCCHHHHHHH	24.69	28889911
6	Phosphorylation	--MSTAVTFFGQHVL --CCCHHHHHHHHHH	15.69	28889911
154	Acetylation	VTRDHIFKQTNEDAS CCHHHHHHHCCCCCH	56.46	24489116
169	Phosphorylation	LYSQGKMYLDWLAKY HHHCCCHHHHHHHHC	12.66	22890988
176	Phosphorylation	YLDWLAKYKFCPGCG HHHHHHHCCCCCCCC	12.04	22890988
252	Phosphorylation	RYGDFVLYSTIAGFM HHCCEEEEEECCCCC	9.85	27017623
264	Phosphorylation	GFMEPSETIEEACIR CCCCCCHHHHHHHHH	37.72	27017623
277	Phosphorylation	IREIWEETGISCKNI HHHHHHHHCCCCCCC	28.44	27017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of NPY1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of NPY1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of NPY1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YRA1_YEAST	YRA1	physical	16554755
LSM12_YEAST	LSM12	physical	16554755
SPC34_YEAST	SPC34	physical	16554755
CDC31_YEAST	CDC31	physical	16554755
RXT2_YEAST	RXT2	genetic	19269370
STE50_YEAST	STE50	genetic	19269370
KCS1_YEAST	KCS1	genetic	19269370
SWR1_YEAST	SWR1	genetic	19269370
VPS72_YEAST	VPS72	genetic	19269370
VPS71_YEAST	VPS71	genetic	19269370
H2AZ_YEAST	HTZ1	genetic	19269370
TAF5_YEAST	TAF5	genetic	27708008
FBRL_YEAST	NOP1	genetic	27708008
TAF12_YEAST	TAF12	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
PAN1_YEAST	PAN1	genetic	27708008
RU1C_YEAST	YHC1	genetic	27708008
BUR1_YEAST	SGV1	genetic	27708008
KPYK1_YEAST	CDC19	genetic	27708008
SEC17_YEAST	SEC17	genetic	27708008
ALG14_YEAST	ALG14	genetic	27708008
RIB7_YEAST	RIB7	genetic	27708008
MED8_YEAST	MED8	genetic	27708008
KIN28_YEAST	KIN28	genetic	27708008
COPA_YEAST	COP1	genetic	27708008
TIM22_YEAST	TIM22	genetic	27708008
FAL1_YEAST	FAL1	genetic	27708008
CDC1_YEAST	CDC1	genetic	27708008
TCPA_YEAST	TCP1	genetic	27708008
PCF11_YEAST	PCF11	genetic	27708008
SRPR_YEAST	SRP101	genetic	27708008
GPI19_YEAST	GPI19	genetic	27708008
RSP5_YEAST	RSP5	genetic	27708008
CDC4_YEAST	CDC4	genetic	27708008
MOB2_YEAST	MOB2	genetic	27708008
RSC8_YEAST	RSC8	genetic	27708008
DAM1_YEAST	DAM1	genetic	27708008
RRP41_YEAST	SKI6	genetic	27708008
SYMC_YEAST	MES1	genetic	27708008
YHI0_YEAST	YHR020W	genetic	27708008
RRP4_YEAST	RRP4	genetic	27708008
CDC23_YEAST	CDC23	genetic	27708008
STS1_YEAST	STS1	genetic	27708008
ARP4_YEAST	ARP4	genetic	27708008
ESS1_YEAST	ESS1	genetic	27708008
ABF1_YEAST	ABF1	genetic	27708008
RSC4_YEAST	RSC4	genetic	27708008
BET3_YEAST	BET3	genetic	27708008
SEN1_YEAST	SEN1	genetic	27708008
RSC9_YEAST	RSC9	genetic	27708008
MED11_YEAST	MED11	genetic	27708008
LCB1_YEAST	LCB1	genetic	27708008
LST8_YEAST	LST8	genetic	27708008
TIM23_YEAST	TIM23	genetic	27708008
SEC12_YEAST	SEC12	genetic	27708008
MED7_YEAST	MED7	genetic	27708008
GRPE_YEAST	MGE1	genetic	27708008
TIM50_YEAST	TIM50	genetic	27708008
NAB3_YEAST	NAB3	genetic	27708008
HRR25_YEAST	HRR25	genetic	27708008
CET1_YEAST	CET1	genetic	27708008
ARP7_YEAST	ARP7	genetic	27708008
IWS1_YEAST	SPN1	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of NPY1_YEAST

Related Literatures of Post-Translational Modification