| UniProt ID | ALG14_YEAST | |
|---|---|---|
| UniProt AC | P38242 | |
| Protein Name | UDP-N-acetylglucosamine transferase subunit ALG14 | |
| Gene Name | ALG14 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 237 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Single-pass membrane protein . Nucleus membrane Single-pass membrane protein . |
|
| Protein Description | Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER.. | |
| Protein Sequence | MKTAYLASLVLIVSTAYVIRLIAILPFFHTQAGTEKDTKDGVNLLKIRKSSKKPLKIFVFLGSGGHTGEMIRLLENYQDLLLGKSIVYLGYSDEASRQRFAHFIKKFGHCKVKYYEFMKAREVKATLLQSVKTIIGTLVQSFVHVVRIRFAMCGSPHLFLLNGPGTCCIISFWLKIMELLLPLLGSSHIVYVESLARINTPSLTGKILYWVVDEFIVQWQELRDNYLPRSKWFGILV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 113 | Acetylation | KFGHCKVKYYEFMKA HHCCCEEEHHHHHHH | 27.84 | 24489116 | |
| 126 | Phosphorylation | KAREVKATLLQSVKT HHHHHHHHHHHHHHH | 23.45 | 17563356 | |
| 130 | Phosphorylation | VKATLLQSVKTIIGT HHHHHHHHHHHHHHH | 26.08 | 17563356 | |
| 155 | Phosphorylation | IRFAMCGSPHLFLLN HHHHHCCCCEEEECC | 12.29 | 29688323 | |
| 166 | Phosphorylation | FLLNGPGTCCIISFW EECCCCCCHHHHHHH | 13.82 | 29688323 | |
| 171 | Phosphorylation | PGTCCIISFWLKIME CCCHHHHHHHHHHHH | 7.17 | 29688323 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ALG14_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ALG14_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ALG14_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-126 AND SER-130, ANDMASS SPECTROMETRY. | |
