ICT1_YEAST - dbPTM
ICT1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ICT1_YEAST
UniProt AC Q12385
Protein Name 1-acylglycerol-3-phosphate O-acyltransferase ICT1
Gene Name ICT1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 394
Subcellular Localization
Protein Description Lysophosphatidic acid acyltransferase involved in membrane remodeling leading to increased organic solvent tolerance. Involved in resistance to azoles and copper..
Protein Sequence MWTNTFKWCSKTEKETTTADAKVCASVQGLKALQQQIMDSTTVRGSVNNTMTPGGINQWHFHNKRANKVCTPTVLIHGYAASSMAFYRTFENLSDNIKDLYAIDLPANGASEAPALQVNKTKKIKSLRFKHIEDDVVIPVIEKRPPAEDIKSHLEQYESYFVDRIEQWRKDNKLRKINVVGHSFGGYISFKYALKYPDSIEKLCLISPLGVENSIHAITHKWEPNTTYPLTFTDPSSRYYTRKLNVPRFIFENQLNVLKWMGPIGSKLCSNYISTAYVKVPDQIYKDYLLHSFVGKNQTVQPQTIKVFTHLFERNLIARDPIINNVRFLNPATPVMFMYGEHDWMDKYAGYLTTESMLKNKAKASYVEVPDAGHNLFLDNPQHFASSLVSFLSK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
50PhosphorylationVRGSVNNTMTPGGIN
EEECCCCCCCCCCCC		19.7429650682
199PhosphorylationYALKYPDSIEKLCLI
EEECCCCCHHHHEEE		28.3027017623
348PhosphorylationEHDWMDKYAGYLTTE
CCCHHHHHHCCCCHH		10.8628889911
351PhosphorylationWMDKYAGYLTTESML
HHHHHHCCCCHHHHH		7.8428889911
353PhosphorylationDKYAGYLTTESMLKN
HHHHCCCCHHHHHCC		21.7528889911
354PhosphorylationKYAGYLTTESMLKNK
HHHCCCCHHHHHCCC		24.3828889911
356PhosphorylationAGYLTTESMLKNKAK
HCCCCHHHHHCCCCC		27.5928889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ICT1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ICT1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ICT1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SHE1_YEASTSHE1genetic
27708008
MRM2_YEASTMRM2genetic
27708008
GID4_YEASTVID24genetic
27708008
KTR4_YEASTKTR4genetic
27708008
MAL33_YEASTMAL33genetic
27708008
PER1_YEASTPER1genetic
27708008
SAC7_YEASTSAC7genetic
27708008
SAK1_YEASTSAK1genetic
27708008
PALF_YEASTRIM8genetic
27708008
TYW3_YEASTTYW3genetic
27708008
YG5X_YEASTYGR283Cgenetic
27708008
THP2_YEASTTHP2genetic
27708008
ASF1_YEASTASF1genetic
27708008
RL14A_YEASTRPL14Agenetic
27708008
HCS1_YEASTHCS1genetic
27708008
RNH2A_YEASTRNH201genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ICT1_YEAST

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Related Literatures of Post-Translational Modification

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