| UniProt ID | GID4_YEAST | |
|---|---|---|
| UniProt AC | P38263 | |
| Protein Name | Vacuolar import and degradation protein 24 | |
| Gene Name | VID24 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 362 | |
| Subcellular Localization |
Cytoplasmic vesicle membrane Peripheral membrane protein . FBPase-containing vesicles. |
|
| Protein Description | Has a role in the negative regulation of gluconeogenesis. Required for both proteasome-dependent and vacuolar catabolite degradation of fructose-1,6-bisphosphatase (FBPase). Probably regulates FBPase targeting from the FBPase-containing vesicles to the vacuole.. | |
| Protein Sequence | MINNPKVDSVAEKPKAVTSKQSEQAASPEPTPAPPVSRNQYPITFNLTSTAPFHLHDRHRYLQEQDLYKCASRDSLSSLQQLAHTPNGSTRKKYIVEDQSPYSSENPVIVTSSYNHTVCTNYLRPRMQFTGYQISGYKRYQVTVNLKTVDLPKKDCTSLSPHLSGFLSIRGLTNQHPEISTYFEAYAVNHKELGFLSSSWKDEPVLNEFKATDQTDLEHWINFPSFRQLFLMSQKNGLNSTDDNGTTNAAKKLPPQQLPTTPSADAGNISRIFSQEKQFDNYLNERFIFMKWKEKFLVPDALLMEGVDGASYDGFYYIVHDQVTGNIQGFYYHQDAEKFQQLELVPSLKNKVESSDCSFEFA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 6 | Ubiquitination | --MINNPKVDSVAEK --CCCCCCCCCCCCC | 17644757 | ||
| 13 | Ubiquitination | KVDSVAEKPKAVTSK CCCCCCCCCCCCCCH | 23749301 | ||
| 15 | Ubiquitination | DSVAEKPKAVTSKQS CCCCCCCCCCCCHHH | 23749301 | ||
| 20 | Ubiquitination | KPKAVTSKQSEQAAS CCCCCCCHHHHCCCC | 23749301 | ||
| 27 | Phosphorylation | KQSEQAASPEPTPAP HHHHCCCCCCCCCCC | 21082442 | ||
| 69 | Ubiquitination | LQEQDLYKCASRDSL HCHHCHHHHCCCCCH | 17644757 | ||
| 75 | Phosphorylation | YKCASRDSLSSLQQL HHHCCCCCHHHHHHH | 23749301 | ||
| 85 | Phosphorylation | SLQQLAHTPNGSTRK HHHHHHCCCCCCCCC | 28889911 | ||
| 92 | Ubiquitination | TPNGSTRKKYIVEDQ CCCCCCCCEEEECCC | 17644757 | ||
| 93 | Ubiquitination | PNGSTRKKYIVEDQS CCCCCCCEEEECCCC | 17644757 | ||
| 138 | Ubiquitination | GYQISGYKRYQVTVN EEEECCEEEEEEEEE | 17644757 | ||
| 153 | Ubiquitination | LKTVDLPKKDCTSLS EEECCCCCCCCCCCC | 17644757 | ||
| 154 | Ubiquitination | KTVDLPKKDCTSLSP EECCCCCCCCCCCCH | 17644757 | ||
| 191 | Ubiquitination | EAYAVNHKELGFLSS EEEECCHHHHCCCCC | 17644757 | ||
| 210 | Ubiquitination | EPVLNEFKATDQTDL CCCHHCCCCCCCCCH | 17644757 | ||
| 235 | Ubiquitination | QLFLMSQKNGLNSTD HHHHHHHCCCCCCCC | 17644757 | ||
| 251 | Ubiquitination | NGTTNAAKKLPPQQL CCCCCHHHHCCHHHC | 17644757 | ||
| 252 | Ubiquitination | GTTNAAKKLPPQQLP CCCCHHHHCCHHHCC | 23749301 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GID4_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GID4_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GID4_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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