GID8_YEAST - dbPTM
GID8_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GID8_YEAST
UniProt AC P40208
Protein Name Glucose-induced degradation protein 8
Gene Name GID8
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 455
Subcellular Localization Nucleus . Cytoplasm .
Protein Description Has a role in the negative regulation of gluconeogenesis. Required for proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase). Required also for cell cycle progression. Positively controls G1 and the timing of START..
Protein Sequence MTISTLSNETTKSGSCSGQGKNGGKDFTYGKKCFTKEEWKEQVAKYSAMGELYANKTIHYPLKIQPNSSGGSQDEGFATIQTTPIEPTLPRLLLNYFVSMAYEDSSIRMAKELGFIRNNKDIAVFNDLYKIKERFHIKHLIKLGRINEAMEEINSIFGLEVLEETFNATGSYTGRTDRQQQQQQQQFDIDGDLHFKLLLLNLIEMIRSHHQQENITKDSNDFILNLIQYSQNKLAIKASSSVKKMQELELAMTLLLFPLSDSADSGSIKLPKSLQNLYSISLRSKIADLVNEKLLKFIHPRIQFEISNNNSKFPDLLNSDKKIITQNFTVYNNNLVNGSNGTKITHISSDQPINEKMSSNEVTAAANSVWLNQRDGNVGTGSAATTFHNLENKNYWNQTSELLSSSNGKEKGLEFNNYYSSEFPYEPRLTQIMKLWCWCENQLHHNQIGVPRVEN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MTISTLSNE
------CCCCCCCCC		24.5122369663
4Phosphorylation----MTISTLSNETT
----CCCCCCCCCCC		17.7122369663
7Phosphorylation-MTISTLSNETTKSG
-CCCCCCCCCCCCCC		32.4822369663
10PhosphorylationISTLSNETTKSGSCS
CCCCCCCCCCCCCCC		43.7222369663
11PhosphorylationSTLSNETTKSGSCSG
CCCCCCCCCCCCCCC		19.6222369663
68PhosphorylationPLKIQPNSSGGSQDE
CEECCCCCCCCCCCC		36.7230377154
69PhosphorylationLKIQPNSSGGSQDEG
EECCCCCCCCCCCCC		54.5419779198
72PhosphorylationQPNSSGGSQDEGFAT
CCCCCCCCCCCCEEE		37.6723749301
120AcetylationLGFIRNNKDIAVFND
HCCCCCCCCEEEECC		54.8024489116
240PhosphorylationKLAIKASSSVKKMQE
HHHHHCCHHHHHHHH		43.9728889911
349PhosphorylationTKITHISSDQPINEK
CEEEECCCCCCCCCC		39.3923749301
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GID8_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GID8_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GID8_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
DCR2_YEASTDCR2genetic
15590836
GID4_YEASTVID24physical
16554755
RMD5_YEASTRMD5physical
16554755
VID28_YEASTVID28physical
16554755
VID30_YEASTVID30physical
16872538
VID28_YEASTVID28physical
16872538
YD176_YEASTYDL176Wphysical
16872538
FYV10_YEASTFYV10physical
16872538
GID8_YEASTGID8physical
16872538
RMD5_YEASTRMD5physical
16872538
ODPA_YEASTPDA1genetic
17314980
GID7_YEASTGID7physical
18719252
ETR1_YEASTETR1genetic
20093466
CSG2_YEASTCSG2genetic
20093466
AIM4_YEASTAIM4genetic
20093466
ODPB_YEASTPDB1genetic
20093466
SNF5_YEASTSNF5genetic
20093466
TXTP_YEASTCTP1genetic
20093466
RV161_YEASTRVS161genetic
20093466
PRM7_YEASTPRM7genetic
20093466
MAF1_YEASTMAF1genetic
20093466
TRS85_YEASTTRS85genetic
20093466
DHSD_YEASTSDH4genetic
20093466
UME6_YEASTUME6genetic
20093466
SEM1_YEASTSEM1genetic
20093466
RV167_YEASTRVS167genetic
20093466
ODPA_YEASTPDA1genetic
20093466
XRN1_YEASTXRN1genetic
20093466
PSA3_YEASTPRE9genetic
20093466
ODPX_YEASTPDX1genetic
20093466
NPR3_YEASTNPR3genetic
20093466
HTD2_YEASTHTD2genetic
20093466
URM1_YEASTURM1genetic
20093466
RPA34_YEASTRPA34genetic
20093466
LPLA_YEASTAIM22genetic
20093466
FABG_YEASTOAR1genetic
20093466
LIPB_YEASTLIP2genetic
20093466
SCS7_YEASTSCS7genetic
20093466
ODP2_YEASTLAT1genetic
20093466
COX5A_YEASTCOX5Agenetic
20093466
DOM34_YEASTDOM34genetic
20093466
SIN3_YEASTSIN3genetic
20093466
LIPA_YEASTLIP5genetic
20093466
SEC7_YEASTSEC7genetic
27708008
REI1_YEASTREI1genetic
27708008
TFC3_YEASTTFC3genetic
27708008
CDC10_YEASTCDC10genetic
27708008
DAD1_YEASTDAD1genetic
27708008
CDC1_YEASTCDC1genetic
27708008
COG3_YEASTCOG3genetic
27708008
CDC11_YEASTCDC11genetic
27708008
SEN1_YEASTSEN1genetic
27708008
TIM23_YEASTTIM23genetic
27708008
DPM1_YEASTDPM1genetic
27708008
ETR1_YEASTETR1genetic
27708008
SEC66_YEASTSEC66genetic
27708008
AIM4_YEASTAIM4genetic
27708008
ODPB_YEASTPDB1genetic
27708008
TXTP_YEASTCTP1genetic
27708008
MAF1_YEASTMAF1genetic
27708008
TPS2_YEASTTPS2genetic
27708008
ARO1_YEASTARO1genetic
27708008
PEX7_YEASTPEX7genetic
27708008
UME6_YEASTUME6genetic
27708008
ODPA_YEASTPDA1genetic
27708008
XRN1_YEASTXRN1genetic
27708008
PSA3_YEASTPRE9genetic
27708008
ODPX_YEASTPDX1genetic
27708008
ELP2_YEASTELP2genetic
27708008
NPR3_YEASTNPR3genetic
27708008
HTD2_YEASTHTD2genetic
27708008
URM1_YEASTURM1genetic
27708008
FMC1_YEASTFMC1genetic
27708008
CBT1_YEASTCBT1genetic
27708008
SWI6_YEASTSWI6genetic
27708008
ORM2_YEASTORM2genetic
27708008
ODP2_YEASTLAT1genetic
27708008
SIN3_YEASTSIN3genetic
27708008
SDHF2_YEASTSDH5genetic
27708008
UBA3_YEASTUBA3genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GID8_YEAST

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Related Literatures of Post-Translational Modification

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