| UniProt ID | RMD5_YEAST | |
|---|---|---|
| UniProt AC | Q12508 | |
| Protein Name | Sporulation protein RMD5 | |
| Gene Name | RMD5 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 421 | |
| Subcellular Localization | Cytoplasm . | |
| Protein Description | Has a role in the negative regulation of gluconeogenesis. Required for proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase). Required specifically for the ubiquitination of FBPase. Also required for sporulation.. | |
| Protein Sequence | MSELLDSFETEFAKFYTDSNLEETNLQKCLDHTHEFKSQLKKLKAHLNKHIQESKPEVYNKLSDKEKQKFKRKRELIIEKLSKSQRQWDHSVKKQIKYVSQQSNRFNKSTLNKLKEFDIDSVYVNKLPKETMENVNEAIGYHILRYSIDNMPLGNKNEAFQYLKDVYGITNKESTEFIEMGQIVHDLKKGDTESCLKWCSNEMESLSSNHTALSSLKFDLYTLSAMQIVKHGNPVELYYQITQNAPLDCFRHREKELMQNVVPLLTKSLIGQPIEDIDSKVNKELKECTSLFIKEYCAAKHIFFDSPLFLIVLSGLISFQFFIKYKTIRELAHVDWTTKDELPFDVKLPDFLTHFHPIFICPVLKEETTTENPPYSLACHHIISKKALDRLSKNGTITFKCPYCPVNTSMSSTKKVRFVML | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 80 | Acetylation | KRELIIEKLSKSQRQ HHHHHHHHHCHHHHH | 47.88 | 24489116 | |
| 368 | Phosphorylation | CPVLKEETTTENPPY ECCCCCCCCCCCCCC | 39.86 | 27017623 | |
| 370 | Phosphorylation | VLKEETTTENPPYSL CCCCCCCCCCCCCHH | 40.98 | 27017623 | |
| 376 | Phosphorylation | TTENPPYSLACHHII CCCCCCCHHHHHHHH | 18.44 | 27017623 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RMD5_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RMD5_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RMD5_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| RPC8_YEAST | RPC25 | physical | 10688190 | |
| SIF2_YEAST | SIF2 | genetic | 17314980 | |
| VID30_YEAST | VID30 | genetic | 17986252 | |
| FYV10_YEAST | FYV10 | physical | 22044534 | |
| VID30_YEAST | VID30 | physical | 22645139 | |
| COG3_YEAST | COG3 | genetic | 27708008 | |
| BET5_YEAST | BET5 | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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