HTD2_YEAST - dbPTM
HTD2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HTD2_YEAST
UniProt AC P38790
Protein Name Hydroxyacyl-thioester dehydratase type 2, mitochondrial
Gene Name HTD2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 280
Subcellular Localization Mitochondrion .
Protein Description Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis. Required for respiratory growth and for normal mitochondrial morphology..
Protein Sequence MKSKTWIFRDVLSSHRTKAFDSLLCRRLPVSKATKHLQLGEHFLFFPPSFEKLDRDGYFNYQNPASLLGNPDLRYRRRIWGQGELVQYLPVTLDQEYTCHESIKYVKKIRDEHVVCIERTLLQERPENVSSPMDICLFERRVLMYTNSPANKTAVKMPVGEENYKILKNFTVTDMDIVAYGQMSLNPHRIHWDKEYSRYVEGYDDIIMQGPFSVQLLQKCIQPFLEQPIRQLRYRNLNYIYPNTTLSICQSLSSSSGMYTFQIRDLQKANLVYMKADVFC
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
241PhosphorylationYRNLNYIYPNTTLSI
HCCCCCCCCCCHHHH
4.6928132839
259PhosphorylationLSSSSGMYTFQIRDL
CCCCCCEEEEEEEEH
14.1328132839

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HTD2_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HTD2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HTD2_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
VPS8_YEASTVPS8genetic
20093466
RS8A_YEASTRPS8Agenetic
20093466
RS8B_YEASTRPS8Agenetic
20093466
ACH1_YEASTACH1genetic
20093466
UBP14_YEASTUBP14genetic
20093466
GID4_YEASTVID24genetic
20093466
CLPX_YEASTMCX1genetic
20093466
SPS22_YEASTSPS22genetic
20093466
THRC_YEASTTHR4genetic
20093466
YCY0_YEASTYCR090Cgenetic
20093466
YCZ2_YEASTYCR102Cgenetic
20093466
S2538_YEASTYDL119Cgenetic
20093466
QRI7_YEASTQRI7genetic
20093466
RLA1_YEASTRPP1Agenetic
20093466
PEX19_YEASTPEX19genetic
20093466
OCA6_YEASTOCA6genetic
20093466
VPS41_YEASTVPS41genetic
20093466
UBC13_YEASTUBC13genetic
20093466
ARO1_YEASTARO1genetic
20093466
CHL4_YEASTCHL4genetic
20093466
YGY5_YEASTYGL235Wgenetic
20093466
GCN1_YEASTGCN1genetic
20093466
MED5_YEASTNUT1genetic
20093466
AROC_YEASTARO2genetic
20093466
DBF2_YEASTDBF2genetic
20093466
SERB_YEASTSER2genetic
20093466
SUCB_YEASTLSC2genetic
20093466
OCA5_YEASTOCA5genetic
20093466
FMC1_YEASTFMC1genetic
20093466
VID28_YEASTVID28genetic
20093466
YJQ3_YEASTYJL163Cgenetic
20093466
PYR1_YEASTURA2genetic
20093466
YJ24_YEASTKCH1genetic
20093466
DHOM_YEASTHOM6genetic
20093466
RL14A_YEASTRPL14Agenetic
20093466
EI2BA_YEASTGCN3genetic
20093466
PCKA_YEASTPCK1genetic
20093466
YL050_YEASTYLR050Cgenetic
20093466
ERG3_YEASTERG3genetic
20093466
GLYC_YEASTSHM2genetic
20093466
ORN_YEASTREX2genetic
20093466
MID2_YEASTMID2genetic
20093466
DCR2_YEASTDCR2genetic
20093466
PEX12_YEASTPEX12genetic
20093466
GID8_YEASTGID8genetic
20093466
SWS2_YEASTSWS2genetic
20093466
SIW14_YEASTSIW14genetic
20093466
CISY1_YEASTCIT1genetic
20093466
MED9_YEASTCSE2genetic
20093466
PABS_YEASTABZ1genetic
20093466
BRE5_YEASTBRE5genetic
20093466
SUCA_YEASTLSC1genetic
20093466
AXL1_YEASTAXL1genetic
20093466
ACH1_YEASTACH1genetic
21623372
ALDH5_YEASTALD5genetic
21623372
SUCB_YEASTLSC2genetic
21623372
CEM1_YEASTCEM1genetic
21623372
CISY2_YEASTCIT2genetic
21623372
PYR1_YEASTURA2genetic
21623372
KAD2_YEASTADK1genetic
21623372
CISY1_YEASTCIT1genetic
21623372
FABD_YEASTMCT1genetic
21623372
PYRD_YEASTURA1genetic
21623372
PYRC_YEASTURA4genetic
21623372
GCSH_YEASTGCV3genetic
21623372
FABG_YEASTOAR1genetic
21623372
ADH3_YEASTADH3genetic
21623372
REI1_YEASTREI1genetic
27708008
DBF2_YEASTDBF2genetic
27708008
LPLA_YEASTAIM22genetic
27708008
RL14A_YEASTRPL14Agenetic
27708008
CISY1_YEASTCIT1genetic
27708008
VPS8_YEASTVPS8genetic
27708008
ACH1_YEASTACH1genetic
27708008
RS8A_YEASTRPS8Agenetic
27708008
RS8B_YEASTRPS8Agenetic
27708008
AVT5_YEASTAVT5genetic
27708008
CLPX_YEASTMCX1genetic
27708008
SPS22_YEASTSPS22genetic
27708008
THRC_YEASTTHR4genetic
27708008
TAH1_YEASTTAH1genetic
27708008
GPR1_YEASTGPR1genetic
27708008
PEX19_YEASTPEX19genetic
27708008
QRI7_YEASTQRI7genetic
27708008
S2538_YEASTYDL119Cgenetic
27708008
SRF1_YEASTSRF1genetic
27708008
OCA6_YEASTOCA6genetic
27708008
ARO1_YEASTARO1genetic
27708008
BCS1_YEASTBCS1genetic
27708008
AROC_YEASTARO2genetic
27708008
MED5_YEASTNUT1genetic
27708008
XRN1_YEASTXRN1genetic
27708008
GCN1_YEASTGCN1genetic
27708008
QCR9_YEASTQCR9genetic
27708008
SUCB_YEASTLSC2genetic
27708008
VID28_YEASTVID28genetic
27708008
GSH1_YEASTGSH1genetic
27708008
LSM1_YEASTLSM1genetic
27708008
PYR1_YEASTURA2genetic
27708008
DHOM_YEASTHOM6genetic
27708008
PYRD_YEASTURA1genetic
27708008
EI2BA_YEASTGCN3genetic
27708008
ERG3_YEASTERG3genetic
27708008
PEX13_YEASTPEX13genetic
27708008
ARV1_YEASTARV1genetic
27708008
CTF3_YEASTCTF3genetic
27708008
WAR1_YEASTWAR1genetic
27708008
PEX12_YEASTPEX12genetic
27708008
GCSP_YEASTGCV2genetic
27708008
RAD14_YEASTRAD14genetic
27708008
SIW14_YEASTSIW14genetic
27708008
SWS2_YEASTSWS2genetic
27708008
CY1_YEASTCYT1genetic
27708008
SUCA_YEASTLSC1genetic
27708008
RL21B_YEASTRPL21Bgenetic
27708008
KPC1_YEASTPKC1genetic
29674565
BDF2_YEASTBDF2genetic
29674565
PEX13_YEASTPEX13genetic
29674565
GTR1_YEASTGTR1genetic
29674565
LST8_YEASTLST8genetic
29674565
LSM7_YEASTLSM7genetic
29674565
SLA1_YEASTSLA1genetic
29674565
SHE1_YEASTSHE1genetic
29674565
PP2C1_YEASTPTC1genetic
29674565
SLX5_YEASTSLX5genetic
29674565
RS16A_YEASTRPS16Bgenetic
29674565
RS16B_YEASTRPS16Bgenetic
29674565
RPN6_YEASTRPN6genetic
29674565
NUM1_YEASTNUM1genetic
29674565
DHAS_YEASTHOM2genetic
29674565
TRS23_YEASTTRS23genetic
29674565
LSM6_YEASTLSM6genetic
29674565
SAC7_YEASTSAC7genetic
29674565
SDC1_YEASTSDC1genetic
29674565
SMT3_YEASTSMT3genetic
29674565
SWI4_YEASTSWI4genetic
29674565
BEM2_YEASTBEM2genetic
29674565
COG3_YEASTCOG3genetic
29674565
MED5_YEASTNUT1genetic
29674565
UPF3_YEASTUPF3genetic
29674565
DBF2_YEASTDBF2genetic
29674565
ATC7_YEASTNEO1genetic
29674565
LSM1_YEASTLSM1genetic
29674565
RPA34_YEASTRPA34genetic
29674565
ELM1_YEASTELM1genetic
29674565
KTI12_YEASTKTI12genetic
29674565
SAC1_YEASTSAC1genetic
29674565
VPS51_YEASTVPS51genetic
29674565
CSF1_YEASTCSF1genetic
29674565
GSP1_YEASTGSP1genetic
29674565
TAD3_YEASTTAD3genetic
29674565
PEX30_YEASTPEX30genetic
29674565
POB3_YEASTPOB3genetic
29674565
SUB1_YEASTSUB1genetic
29674565
INP2_YEASTINP2genetic
29674565
SCS7_YEASTSCS7genetic
29674565
BRE5_YEASTBRE5genetic
29674565
ENG1_YEASTDSE4genetic
29674565
YP066_YEASTRGL1genetic
29674565
NEW1_YEASTNEW1genetic
29674565
RPN7_YEASTRPN7genetic
29674565
SEC23_YEASTSEC23genetic
29674565
PEX22_YEASTPEX22genetic
29674565
SIF2_YEASTSIF2genetic
29674565
SNT1_YEASTSNT1genetic
29674565
PAT1_YEASTPAT1genetic
29674565
TPS2_YEASTTPS2genetic
29674565
UBC13_YEASTUBC13genetic
29674565
WDR59_YEASTMTC5genetic
29674565
UME6_YEASTUME6genetic
29674565
FCF1_YEASTFCF1genetic
29674565
GCN20_YEASTGCN20genetic
29674565
GCN1_YEASTGCN1genetic
29674565
UBCX_YEASTPEX4genetic
29674565
RPC9_YEASTRPC17genetic
29674565
TIM16_YEASTPAM16genetic
29674565
TOF2_YEASTTOF2genetic
29674565
EI2BA_YEASTGCN3genetic
29674565
PEX12_YEASTPEX12genetic
29674565
ASE1_YEASTASE1genetic
29674565

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HTD2_YEAST

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Related Literatures of Post-Translational Modification

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