PABS_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PABS_YEAST
• UniProt AC: P37254
• Protein Name: Aminodeoxychorismate synthase
• Gene Name: ABZ1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 787
• Subcellular Localization: Cytoplasm .
• Protein Description: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine. Required for the synthesis of 4-aminobenzoate (PABA), an important component in tetrahydrofolate biosynthesis..
• Protein Sequence: MLSDTIDTKQQQQQLHVLFIDSYDSFTYNVVRLIEQQTDISPGVNAVHVTTVHSDTFQSMDQLLPLLPLFDAIVVGPGPGNPNNGAQDMGIISELFENANGKLDEVPILGICLGFQAMCLAQGADVSELNTIKHGQVYEMHLNDAARACGLFSGYPDTFKSTRYHSLHVNAEGIDTLLPLCTTEDENGILLMSAQTKNKPWFGVQYHPESCCSELGGLLVSNFLKLSFINNVKTGRWEKKKLNGEFSDILSRLDRTIDRDPIYKVKEKYPKGEDTTYVKQFEVSEDPKLTFEICNIIREEKFVMSSSVISENTGEWSIIALPNSASQVFTHYGAMKKTTVHYWQDSEISYTLLKKCLDGQDSDLPGSLEVIHEDKSQFWITLGKFMENKIIDNHREIPFIGGLVGILGYEIGQYIACGRCNDDENSLVPDAKLVFINNSIVINHKQGKLYCISLDNTFPVALEQSLRDSFVRKKNIKQSLSWPKYLPEEIDFIITMPDKLDYAKAFKKCQDYMHKGDSYEMCLTTQTKVVPSAVIEPWRIFQTLVQRNPAPFSSFFEFKDIIPRQDETPPVLCFLSTSPERFLKWDADTCELRPIKGTVKKGPQMNLAKATRILKTPKEFGENLMILDLIRNDLYELVPDVRVEEFMSVQEYATVYQLVSVVKAHGLTSASKKTRYSGIDVLKHSLPPGSMTGAPKKITVQLLQDKIESKLNKHVNGGARGVYSGVTGYWSVNSNGDWSVNIRCMYSYNGGTSWQLGAGGAITVLSTLDGELEEMYNKLESNLQIFM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
706	Acetylation	TVQLLQDKIESKLNK EHHHHHHHHHHHHHH	35.10	24489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PABS_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PABS_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PABS_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ETR1_YEAST	ETR1	genetic	20093466
YD180_YEAST	YDL180W	genetic	20093466
PBP4_YEAST	PBP4	genetic	20093466
NHP10_YEAST	NHP10	genetic	20093466
YD056_YEAST	YDR056C	genetic	20093466
MNN10_YEAST	MNN10	genetic	20093466
PIB1_YEAST	PIB1	genetic	20093466
IRC4_YEAST	IRC4	genetic	20093466
CAJ1_YEAST	CAJ1	genetic	20093466
CEM1_YEAST	CEM1	genetic	20093466
YFF1_YEAST	YFL051C	genetic	20093466
GCN20_YEAST	GCN20	genetic	20093466
CWC26_YEAST	BUD13	genetic	20093466
YG34_YEAST	YGR122W	genetic	20093466
HTD2_YEAST	HTD2	genetic	20093466
LPLA_YEAST	AIM22	genetic	20093466
VPS55_YEAST	VPS55	genetic	20093466
EF1G2_YEAST	TEF4	genetic	20093466
FABG_YEAST	OAR1	genetic	20093466
AMPD_YEAST	AMD1	genetic	20093466
PKR1_YEAST	PKR1	genetic	20093466
RCE1_YEAST	RCE1	genetic	20093466
NST1_YEAST	NST1	genetic	20093466
LIPA_YEAST	LIP5	genetic	20093466
YIG1_YEAST	YIG1	genetic	20093466
PPT2_YEAST	PPT2	genetic	21623372
PDX3_YEAST	PDX3	genetic	21623372
FUN30_YEAST	FUN30	genetic	27708008
ETR1_YEAST	ETR1	genetic	27708008
GLYM_YEAST	SHM1	genetic	27708008
MCH1_YEAST	MCH1	genetic	27708008
YD056_YEAST	YDR056C	genetic	27708008
MNN10_YEAST	MNN10	genetic	27708008
CAJ1_YEAST	CAJ1	genetic	27708008
CEM1_YEAST	CEM1	genetic	27708008
ODPA_YEAST	PDA1	genetic	27708008
YFF1_YEAST	YFL051C	genetic	27708008
MON1_YEAST	MON1	genetic	27708008
CWC26_YEAST	BUD13	genetic	27708008
MDM34_YEAST	MDM34	genetic	27708008
HTD2_YEAST	HTD2	genetic	27708008
FMC1_YEAST	FMC1	genetic	27708008
DOHH_YEAST	LIA1	genetic	27708008
MDM35_YEAST	MDM35	genetic	27708008
FABG_YEAST	OAR1	genetic	27708008
EF1G2_YEAST	TEF4	genetic	27708008
CUE2_YEAST	CUE2	genetic	27708008
LIPB_YEAST	LIP2	genetic	27708008
TMA23_YEAST	TMA23	genetic	27708008
RCE1_YEAST	RCE1	genetic	27708008
LIPA_YEAST	LIP5	genetic	27708008
KAR9_YEAST	KAR9	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.