RPC9_YEAST - dbPTM
RPC9_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RPC9_YEAST
UniProt AC P47076
Protein Name DNA-directed RNA polymerase III subunit RPC9
Gene Name RPC17
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 161
Subcellular Localization Nucleus .
Protein Description DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. The RPC25/RPC8-RPC17/RPC9 subcomplex may bind Pol III transcripts emerging from the adjacent exit pore during elongation..
Protein Sequence MKVLEERNAFLSDYEVLKFLTDLEKKHLWDQKSLAALKKSRSKGKQNRPYNHPELQGITRNVVNYLSINKNFINQEDEGEERESSGAKDAEKSGISKMSDESFAELMTKLNSFKLFKAEKLQIVNQLPANMVHLYSIVEECDARFDEKTIEEMLEIISGYA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
32AcetylationKKHLWDQKSLAALKK
HHCCCCHHHHHHHHH
44.9924489116
33PhosphorylationKHLWDQKSLAALKKS
HCCCCHHHHHHHHHH
20.0126447709
40PhosphorylationSLAALKKSRSKGKQN
HHHHHHHHHCCCCCC
39.9526447709
84PhosphorylationDEGEERESSGAKDAE
CCCCCCCCCCCCHHH
40.0522369663
85PhosphorylationEGEERESSGAKDAEK
CCCCCCCCCCCHHHH
37.7122369663
99PhosphorylationKSGISKMSDESFAEL
HHCCCCCCHHHHHHH
41.8028152593

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RPC9_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RPC9_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RPC9_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RPC2_YEASTRET1physical
14759368
RPC9_YEASTRPC17physical
14759368
RPC8_YEASTRPC25physical
14759368
RPC6_YEASTRPC34physical
14759368
RPC5_YEASTRPC37physical
14759368
RPC3_YEASTRPC82physical
14759368
RPC1_YEASTRPO31physical
14759368
RPAC1_YEASTRPC40physical
14759368
RPC8_YEASTRPC25physical
12482973
RPC7_YEASTRPC31physical
10611227
TF3B_YEASTBRF1physical
10611227
RPC10_YEASTRPC11physical
10611227
RPAB1_YEASTRPB5physical
16554755
RPC8_YEASTRPC25physical
16554755
RPC5_YEASTRPC37physical
16554755
RPAC2_YEASTRPC19physical
16554755
RPC7_YEASTRPC31physical
16554755
RPC1_YEASTRPO31physical
16554755
RPC2_YEASTRET1physical
16554755
RPAC1_YEASTRPC40physical
16554755
RPC3_YEASTRPC82physical
16554755
MRT4_YEASTMRT4genetic
19061648
GBLP_YEASTASC1genetic
19061648
THP2_YEASTTHP2physical
18719252
PUT3_YEASTPUT3physical
18719252
ADA2_YEASTADA2physical
18719252
TOS8_YEASTTOS8physical
18719252
RPC8_YEASTRPC25physical
16818233

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RPC9_YEAST

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Related Literatures of Post-Translational Modification

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