| UniProt ID | RS14B_YEAST | |
|---|---|---|
| UniProt AC | P39516 | |
| Protein Name | 40S ribosomal protein S14-B {ECO:0000303|PubMed:9559554} | |
| Gene Name | RPS14B {ECO:0000303|PubMed:9559554} | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 138 | |
| Subcellular Localization | Cytoplasm . Nucleus, nucleolus . | |
| Protein Description | Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. [PubMed: 22096102 uS11 is involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly] | |
| Protein Sequence | MANDLVQARDNSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 12 | Phosphorylation | LVQARDNSQVFGVAR CCCCCCCCCEEEEEE | 31.82 | 22369663 | |
| 23 | Phosphorylation | GVARIYASFNDTFVH EEEEEEEECCCCEEE | 13.96 | 30377154 | |
| 37 | Ubiquitination | HVTDLSGKETIARVT EEEECCCCCEEEEEC | 48.59 | 23749301 | |
| 44 | Phosphorylation | KETIARVTGGMKVKA CCEEEEECCCCEEEE | 23.59 | 28889911 | |
| 48 | Ubiquitination | ARVTGGMKVKADRDE EEECCCCEEEECCCC | 43.81 | 23749301 | |
| 50 | Ubiquitination | VTGGMKVKADRDESS ECCCCEEEECCCCCC | 38.77 | 24961812 | |
| 59 | Phosphorylation | DRDESSPYAAMLAAQ CCCCCCHHHHHHHHH | 14.67 | 21440633 | |
| 71 | Ubiquitination | AAQDVAAKCKEVGIT HHHHHHHHCCCCCCE | 35.78 | 23749301 | |
| 73 | Ubiquitination | QDVAAKCKEVGITAV HHHHHHCCCCCCEEE | 55.52 | 23749301 | |
| 92 | Phosphorylation | RATGGTRTKTPGPGG EECCCCCCCCCCCCH | 38.82 | 23749301 | |
| 93 | Ubiquitination | ATGGTRTKTPGPGGQ ECCCCCCCCCCCCHH | 49.81 | 23749301 | |
| 94 | Phosphorylation | TGGTRTKTPGPGGQA CCCCCCCCCCCCHHH | 32.63 | 29136822 | |
| 120 | Phosphorylation | IGRIEDVTPVPSDST EECEEECCCCCCCCC | 30.78 | 22369663 | |
| 124 | Phosphorylation | EDVTPVPSDSTRKKG EECCCCCCCCCCCCC | 44.41 | 22369663 | |
| 126 | Phosphorylation | VTPVPSDSTRKKGGR CCCCCCCCCCCCCCC | 34.15 | 24909858 | |
| 127 | Phosphorylation | TPVPSDSTRKKGGRR CCCCCCCCCCCCCCC | 52.04 | 19779198 | |
| 129 | Ubiquitination | VPSDSTRKKGGRRGR CCCCCCCCCCCCCCC | 56.72 | 17644757 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RS14B_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RS14B_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RS14B_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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