YKK0_YEAST - dbPTM
YKK0_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID YKK0_YEAST
UniProt AC P34248
Protein Name Probable intramembrane protease YKL100C
Gene Name YKL100C
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 587
Subcellular Localization Membrane
Multi-pass membrane protein. Endoplasmic reticulum membrane
Multi-pass membrane protein.
Protein Description May act as intramembrane protease..
Protein Sequence MDKYLNSFVDHLSEWSSRAFRNNSSSANQSASNKELEQVFEQINAIVENHNNKLTTAFDKISYRVAHKITHLVESHSLVFNYATLVLIASALVVIGSFTSISSIPFTALPPTREHSLFDPTDFDVDHDCHVIYRENDEDKKKKKKSKRFFDMMDEKHAIILPLTSGCTLLALYFVIKKLHLNWLKYVVKILNFNITLLNIPAGTFVYSYFLNSLFRNLSHLASWNPLVVLPRYRVTIADDNEDLNKIGGFVTNLNYKDGLTNSVVHKKTLDEIEKDHWMKHFYRRELVEPKDIKSKRQISNMYLNSALIVSFVLSIVSTVYFYLSPNDWLISNAVSMNMAIWSIAQLKLKNLKSGALILIALFFYDICFVFGTDVMVTVATNLDIPVKLSLPVKFNTAQNNFNFSILGLGDIALPGMFIAMCYKYDIWKWHLDHDDTEFHFLNWSYVGKYFITAMVSYVASLVSAMVSLSIFNTAQPALLYIVPSLLISTILVACWNKDFKQFWNFQYDTIEVDKSLKKAIEKKENSITYSTFILSEYYNDADKYALLGDDVNENFDDDEEFVQEEDLSDSSEEELSEEDLLDDESS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
3Ubiquitination-----MDKYLNSFVD
-----CHHHHHHHHH		50.7917644757
60AcetylationKLTTAFDKISYRVAH
CCCHHHHHHHHHHHH		27.3924489116
246UbiquitinationDDNEDLNKIGGFVTN
CCCCHHHHHCCEECC		50.4523749301
257UbiquitinationFVTNLNYKDGLTNSV
EECCCCCCCCCCCCC		44.2224961812
257AcetylationFVTNLNYKDGLTNSV
EECCCCCCCCCCCCC		44.2224489116
275AcetylationKTLDEIEKDHWMKHF
HHHHHHHHHHHHHHH		61.6324489116
280AcetylationIEKDHWMKHFYRREL
HHHHHHHHHHHHHHC		25.9324489116
527PhosphorylationAIEKKENSITYSTFI
HHHHHCCCCCHHHHH		19.8724961812
529PhosphorylationEKKENSITYSTFILS
HHHCCCCCHHHHHHH		15.9624961812
530PhosphorylationKKENSITYSTFILSE
HHCCCCCHHHHHHHH		12.2124961812
531PhosphorylationKENSITYSTFILSEY
HCCCCCHHHHHHHHH		14.2724961812
532PhosphorylationENSITYSTFILSEYY
CCCCCHHHHHHHHHC		12.3224961812
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of YKK0_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of YKK0_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of YKK0_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
AVT5_YEASTAVT5genetic
20093466
GID4_YEASTVID24genetic
20093466
PUS2_YEASTPUS2genetic
20093466
TGS1_YEASTTGS1genetic
20093466
ZRT1_YEASTZRT1physical
25454947
DFM1_YEASTDFM1physical
25454947
AVT5_YEASTAVT5genetic
27708008
RL35A_YEASTRPL35Agenetic
27708008
RL35B_YEASTRPL35Agenetic
27708008
FMP16_YEASTFMP16genetic
27708008
TRM1_YEASTTRM1genetic
27708008
NKP1_YEASTNKP1genetic
27708008
ASK10_YEASTASK10genetic
27708008
GSH1_YEASTGSH1genetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
YJ94_YEASTYJR124Cgenetic
27708008
RL31B_YEASTRPL31Bgenetic
27708008
RIM11_YEASTRIM11genetic
27708008
MET22_YEASTMET22genetic
27708008
VAM3_YEASTVAM3genetic
27708008
TGS1_YEASTTGS1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of YKK0_YEAST

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Related Literatures of Post-Translational Modification

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