ZRT1_YEAST - dbPTM
ZRT1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZRT1_YEAST
UniProt AC P32804
Protein Name Zinc-regulated transporter 1
Gene Name ZRT1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 376
Subcellular Localization Membrane
Multi-pass membrane protein .
Protein Description High-affinity zinc transport protein..
Protein Sequence MSNVTTPWWKQWDPSEVTLADKTPDDVWKTCVLQGVYFGGNEYNGNLGARISSVFVILFVSTFFTMFPLISTKVKRLRIPLYVYLFAKYFGSGVIVATAFIHLMDPAYGAIGGTTCVGQTGNWGLYSWCPAIMLTSLTFTFLTDLFSSVWVERKYGLSHDHTHDEIKDTVVRNTAAVSSENDNENGTANGSHDTKNGVEYYEDSDATSMDVVQSFQAQFYAFLILEFGVIFHSVMIGLNLGSVGDEFSSLYPVLVFHQSFEGLGIGARLSAIEFPRSKRWWPWALCVAYGLTTPICVAIGLGVRTRYVSGSYTALVISGVLDAISAGILLYTGLVELLARDFIFNPQRTKDLRELSFNVICTLFGAGIMALIGKWA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
22AcetylationSEVTLADKTPDDVWK
HHCCCCCCCCCHHHH
57.2424489116
155PhosphorylationSVWVERKYGLSHDHT
HHHHHHHHCCCCCCC
29.5322369663
158PhosphorylationVERKYGLSHDHTHDE
HHHHHCCCCCCCHHH
23.6222369663
162PhosphorylationYGLSHDHTHDEIKDT
HCCCCCCCHHHHHHH
36.7622369663
167UbiquitinationDHTHDEIKDTVVRNT
CCCHHHHHHHHHHCC
45.3523793018
167AcetylationDHTHDEIKDTVVRNT
CCCHHHHHHHHHHCC
45.3524489116
169PhosphorylationTHDEIKDTVVRNTAA
CHHHHHHHHHHCCCC
18.8522369663
174PhosphorylationKDTVVRNTAAVSSEN
HHHHHHCCCCCCCCC
12.8722369663
178PhosphorylationVRNTAAVSSENDNEN
HHCCCCCCCCCCCCC
27.4922369663
179PhosphorylationRNTAAVSSENDNENG
HCCCCCCCCCCCCCC
33.5422369663
187PhosphorylationENDNENGTANGSHDT
CCCCCCCCCCCCCCC
28.6522369663
191PhosphorylationENGTANGSHDTKNGV
CCCCCCCCCCCCCCE
20.2822369663
194PhosphorylationTANGSHDTKNGVEYY
CCCCCCCCCCCEEEE
22.4522369663
195UbiquitinationANGSHDTKNGVEYYE
CCCCCCCCCCEEEEC
58.73-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseRSP5P39940
PMID:22199232

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZRT1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZRT1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ZRT2_YEASTZRT2genetic
10856230
ZRT3_YEASTZRT3genetic
10856230
ZRT2_YEASTZRT2genetic
9271382
ZRT2_YEASTZRT2genetic
8798516
PP4R2_YEASTPSY4genetic
17314980
UBP13_YEASTUBP13genetic
17314980
HTL1_YEASTHTL1genetic
17314980
SEC66_YEASTSEC66genetic
17314980
UBX1_YEASTSHP1genetic
17314980
UBC8_YEASTUBC8genetic
17314980
SAS3_YEASTSAS3genetic
17314980
FKBP2_YEASTFPR2genetic
17314980
YBI6_YEASTYBL086Cgenetic
17314980
SPT2_YEASTSPT2genetic
17314980
SSN2_YEASTSSN2genetic
17314980
RKM4_YEASTRKM4genetic
17314980
RAD50_YEASTRAD50genetic
18073441
RAD50_YEASTRAD50genetic
21515092
ETR1_YEASTETR1genetic
21515092
RAD51_YEASTRAD51genetic
21515092
RAD52_YEASTRAD52genetic
21515092
RAD1_YEASTRAD1genetic
21515092
RAD59_YEASTRAD59genetic
21515092
DNLI4_YEASTDNL4genetic
21515092
PRP9_YEASTPRP9genetic
27708008
TAF12_YEASTTAF12genetic
27708008
PCF11_YEASTPCF11genetic
27708008
ACT_YEASTACT1genetic
27708008
NUP85_YEASTNUP85genetic
27708008
ARPC2_YEASTARC35genetic
27708008
NOG2_YEASTNOG2genetic
27708008
PROF_YEASTPFY1genetic
27708008
ERF3_YEASTSUP35genetic
27708008
GPI11_YEASTGPI11genetic
27708008
GPI8_YEASTGPI8genetic
27708008
COG3_YEASTCOG3genetic
27708008
RPN11_YEASTRPN11genetic
27708008
MED14_YEASTRGR1genetic
27708008
VTI1_YEASTVTI1genetic
27708008
IF6_YEASTTIF6genetic
27708008
UBP13_YEASTUBP13genetic
27708008
SEC66_YEASTSEC66genetic
27708008
AP3M_YEASTAPM3genetic
27708008
ATG22_YEASTATG22genetic
27708008
ATG20_YEASTATG20genetic
27708008
YD180_YEASTYDL180Wgenetic
27708008
DTD_YEASTDTD1genetic
27708008
RAD57_YEASTRAD57genetic
27708008
TRS85_YEASTTRS85genetic
27708008
TRM1_YEASTTRM1genetic
27708008
MSC2_YEASTMSC2genetic
27708008
STP1_YEASTSTP1genetic
27708008
BST1_YEASTBST1genetic
27708008
YG2G_YEASTYGR079Wgenetic
27708008
SDS3_YEASTSDS3genetic
27708008
SNX4_YEASTSNX4genetic
27708008
IDS2_YEASTIDS2genetic
27708008
ZRT3_YEASTZRT3genetic
27708008
DOA1_YEASTDOA1genetic
27708008
FRE2_YEASTFRE2genetic
27708008
PTR2_YEASTPTR2genetic
27708008
RL40A_YEASTRPL40Bgenetic
27708008
RL40B_YEASTRPL40Bgenetic
27708008
ZRT2_YEASTZRT2genetic
27708008
ATG23_YEASTATG23genetic
27708008
MDM1_YEASTMDM1genetic
27708008
YM39_YEASTYMR166Cgenetic
27708008
RGM1_YEASTRGM1genetic
27708008
ADH2_YEASTADH2genetic
27708008
UBP15_YEASTUBP15genetic
27708008
YNE0_YEASTYNL040Wgenetic
27708008
COG6_YEASTCOG6genetic
27708008
TOM7_YEASTTOM7genetic
27708008
CMC1_YEASTSAL1genetic
27708008
ZRG17_YEASTZRG17genetic
27708008
BRE5_YEASTBRE5genetic
27708008
YN94_YEASTYNR065Cgenetic
27708008
BSC5_YEASTBSC5genetic
27708008
MPD2_YEASTMPD2genetic
27708008
MSH2_YEASTMSH2genetic
27708008
MPC70_YEASTSPO21genetic
27708008
NDJ1_YEASTNDJ1genetic
27708008
WSC3_YEASTWSC3genetic
27708008
VAM3_YEASTVAM3genetic
27708008
PDR5_YEASTPDR5genetic
27708008
SIZ2_YEASTNFI1genetic
27708008
ODC2_YEASTODC2genetic
27708008
YO223_YEASTDSC3genetic
27708008
YO292_YEASTYOR292Cgenetic
27708008
UBC11_YEASTUBC11genetic
27708008
PPQ1_YEASTPPQ1genetic
27708008
HSP82_YEASTHSP82genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZRT1_YEAST

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Related Literatures of Post-Translational Modification

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