FKBP2_YEAST - dbPTM
FKBP2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FKBP2_YEAST
UniProt AC P32472
Protein Name Peptidyl-prolyl cis-trans isomerase FPR2
Gene Name FPR2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 135
Subcellular Localization Endoplasmic reticulum membrane
Peripheral membrane protein. Is not secreted and probably localized in the endoplasmic reticulum.
Protein Description PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. FKBP-13 may play a role in protein trafficking in the ER..
Protein Sequence MMFNIYLFVTFFSTILAGSLSDLEIGIIKRIPVEDCLIKAMPGDKVKVHYTGSLLESGTVFDSSYSRGSPIAFELGVGRVIKGWDQGVAGMCVGEKRKLQIPSSLAYGERGVPGVIPPSADLVFDVELVDVKSAA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
96AcetylationAGMCVGEKRKLQIPS
CCEEECCCEEECCCC
49.2424489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FKBP2_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FKBP2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FKBP2_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PUF4_YEASTPUF4physical
16554755
MPD2_YEASTMPD2physical
16554755
AP3M_YEASTAPM3genetic
16269340
HSP72_YEASTSSA2physical
22940862
FKBP2_YEASTFPR2physical
22940862
SSB1_YEASTSSB1physical
22940862
RPB7_YEASTRPB7genetic
27708008
RSP5_YEASTRSP5genetic
27708008
SEC65_YEASTSEC65genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FKBP2_YEAST

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Related Literatures of Post-Translational Modification

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