NDJ1_YEAST - dbPTM
NDJ1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NDJ1_YEAST
UniProt AC Q12366
Protein Name Non-disjunction protein 1
Gene Name NDJ1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 352
Subcellular Localization Nucleus . Chromosome, telomere .
Protein Description Required for telomeric clustering (bouquet stage) during meiosis 1 prophase, formation and efficient homolog pairing, meiosis 1 disjunction, and telomere deletion during meiosis. Promotes also meiotic recombination..
Protein Sequence MSKDNRLASILLQPVASSSGNCTEFHDSKLHTLQEELNFLPLEGVASNVCPPMFRGHKNYVFVLYCLNQVDLVTNLQDSTKRYYPLQIFKDCQLSSLVQKDFSHYFQLSRQKEGEDRNDSDTTLVNVVNSGVSRHRSQLLKMCIIPRICSFDKSNSKTYKLIQEYVNRFETVLTKFGPEKDFTKVYANWSKLIESFNELILHDLLVKWQQWSELTQPNATVHQNIPNVLRELVIKLTQRYFTFQPSYSCSIDEFTTILLNKNALSLLDVFRKPRKYKLNFGLWLDCQNGILIFTNGIVQMADEITSERVKSFVRPAHLLVLEDHSNDEAVKKLMFFTFSAILQCFTDEILNC
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
17PhosphorylationILLQPVASSSGNCTE
HHHHCCCCCCCCCCC		25.8527214570
18PhosphorylationLLQPVASSSGNCTEF
HHHCCCCCCCCCCCC		32.3127214570
74PhosphorylationLNQVDLVTNLQDSTK
CCCCCHHHCCCCCCC		37.1928889911
120PhosphorylationEGEDRNDSDTTLVNV
CCCCCCCCCCCHHHH		40.1727214570
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NDJ1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NDJ1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NDJ1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PCH2_YEASTPCH2genetic
17174924
RAD17_YEASTRAD17genetic
17174924
CSM4_YEASTCSM4physical
18818742
RAD4_YEASTRAD4genetic
20093466
YOR1_YEASTYOR1genetic
20093466
RS27B_YEASTRPS27Bgenetic
20093466
LST4_YEASTLST4genetic
20093466
YMD8_YEASTYMD8genetic
20093466
MEK1_YEASTMEK1genetic
20888230
CND2_YEASTBRN1genetic
27708008
RPN12_YEASTRPN12genetic
27708008
CLP1_YEASTCLP1genetic
27708008
PSB6_YEASTPRE7genetic
27708008
PRP6_YEASTPRP6genetic
27708008
TEL2_YEASTTEL2genetic
27708008
MED6_YEASTMED6genetic
27708008
RIF1_YEASTRIF1physical
28455351
ESC8_YEASTESC8physical
28455351
NOP56_YEASTNOP56physical
28455351
NUP2_YEASTNUP2physical
28455351
NUP2_YEASTNUP2genetic
28455351
SPO11_YEASTSPO11genetic
28455351
MPS3_YEASTMPS3physical
25897084
SPC72_YEASTSPC72physical
25897084
RAP1_YEASTRAP1physical
25897084
SPO11_YEASTSPO11genetic
25897084
MPS3_YEASTMPS3genetic
25897084
PO152_YEASTPOM152genetic
25897084
NDJ1_YEASTNDJ1physical
25897084
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NDJ1_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-74, AND MASSSPECTROMETRY.

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