| UniProt ID | MEK1_YEAST | |
|---|---|---|
| UniProt AC | P24719 | |
| Protein Name | Meiosis-specific serine/threonine-protein kinase MEK1 | |
| Gene Name | MEK1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 497 | |
| Subcellular Localization | ||
| Protein Description | Probable protein kinase required for meiotic recombination.. | |
| Protein Sequence | MRPLYSCNLATKDDIEMAGGVAPAHLEVNVGGYNTEQTIPIVKHQLVKVGRNDKECQLVLTNPSISSVHCVFWCVFFDEDSIPMFYVKDCSLNGTYLNGLLLKRDKTYLLKHCDVIELSQGSEENDIKKTRLVFMINDDLQSSLDPKLLDQMGFLREVDQWEITNRIVGNGTFGHVLITHNSKERDEDVCYHPENYAVKIIKLKPNKFDKEARILLRLDHPNIIKVYHTFCDRNNHLYIFQDLIPGGDLFSYLAKGDCLTSMSETESLLIVFQILQALNYLHDQDIVHRDLKLDNILLCTPEPCTRIVLADFGIAKDLNSNKERMHTVVGTPEYCAPEVGFRANRKAYQSFSRAATLEQRGYDSKCDLWSLGVITHIMLTGISPFYGDGSERSIIQNAKIGKLNFKLKQWDIVSDNAKSFVKDLLQTDVVKRLNSKQGLKHIWIAKHLSQLERLYYKKILCNNEGPKLESINSDWKRKLPKSVIISQAIPKKKKVLE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 143 | Phosphorylation | INDDLQSSLDPKLLD ECCHHHHCCCHHHHH | 24.67 | 27214570 | |
| 300 | Phosphorylation | LDNILLCTPEPCTRI CCCEEEECCCCCCEE | 30.56 | 27214570 | |
| 327 | Phosphorylation | SNKERMHTVVGTPEY CCCCCCEEECCCHHH | 13.93 | 27214570 | |
| 331 | Phosphorylation | RMHTVVGTPEYCAPE CCEEECCCHHHCCHH | 11.01 | 27214570 | |
| 350 | Phosphorylation | ANRKAYQSFSRAATL CCHHHHHHHHHHHHH | 16.71 | 27214570 | |
| 356 | Phosphorylation | QSFSRAATLEQRGYD HHHHHHHHHHHCCCC | 29.82 | 27214570 | |
| 364 | Phosphorylation | LEQRGYDSKCDLWSL HHHCCCCCCCCHHHH | 27.05 | 27017623 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MEK1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MEK1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MEK1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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