HED1_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HED1_YEAST
• UniProt AC: Q03937
• Protein Name: Meiosis-specific protein HED1
• Gene Name: HED1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 162
• Subcellular Localization: Nucleus . Chromosome . Localizes as foci on meiotic chromosomes.
• Protein Description: Involved in regulation of meiotic recombination and repair of DNA damage. Inhibits RAD51-mediated recombination when the meiotic recombination machinery is impaired..
• Protein Sequence: MQQRSNRRSCSYIPLGVHNNAEKSLCTEVAPARKNKRSITTSPIVNINVVERRLFNLELEKQQLRAKNLSENTGGGSPNGGAYLDAKKGVREQDQYQGGPSKELDRLQPPPSMKKSPPRKKKSLKDLIYETNKTFYQVDSNKVKYKVGLSKKQLLPSKTVDN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
77	Phosphorylation	SENTGGGSPNGGAYL CCCCCCCCCCCCHHC	20.61	27017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HED1_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HED1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HED1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HED1_YEAST	HED1	physical	16818607
RAD51_YEAST	RAD51	physical	16818607
RAD51_YEAST	RAD51	physical	18347097
HED1_YEAST	HED1	physical	22115747
RAD51_YEAST	RAD51	physical	22115747
HOP1_YEAST	HOP1	genetic	26225562
RAD54_YEAST	RAD54	genetic	24465215

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.