dbPTM

FUB1_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FUB1_YEAST
UniProt AC	P25659
Protein Name	Silencing boundary-establishment protein FUB1 {ECO:0000305\|PubMed:22362029}
Gene Name	FUB1 {ECO:0000303\|PubMed:22362029}
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	250
Subcellular Localization
Protein Description	Plays a role in the establishment of transcriptional silencing boundaries, preventing the propagation of heterochromatic silencing..
Protein Sequence	MIENKVELVAELVLESIGKTEVVSRHTEGTKSCQVSFRIKDSPSEKGSTSFLSELVVIQTLDDNDKYTVVIRHGTSITMACVVGYSDFKLPTELKWPLERESLPVEPDLKPIMTQLKRQTAGSADMPKFDDEYQAQARQNQGTAPLNPYPGLTVTEPSFANPAGGYADGDLYPVGTSHPDWSGGLPNPLGNPSSQGGMIFDPNRRPAPRREDMPPGWMPGSKYDEPFGPGSGGFGGSGSGGFGGSGSGFI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
221	Phosphorylation	PPGWMPGSKYDEPFG CCCCCCCCCCCCCCC		27017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of FUB1_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FUB1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FUB1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PSB3_YEAST	PUP3	physical	16554755
PSA4_YEAST	PRE6	physical	22362029
PSA2_YEAST	PRE8	physical	22362029
PSA3_YEAST	PRE9	physical	22362029
PSB7_YEAST	PRE4	physical	22362029
PSA6_YEAST	PRE5	physical	22362029
PSB6_YEAST	PRE7	physical	22362029
PSB5_YEAST	PRE2	genetic	22362029
RPN1_YEAST	RPN1	genetic	22362029
PRS7_YEAST	RPT1	genetic	22362029
PRS10_YEAST	RPT4	genetic	22362029
PRS8_YEAST	RPT6	genetic	22362029
POC4_YEAST	POC4	genetic	25332237
PSA6_YEAST	PRE5	physical	25332237
PSA5_YEAST	PUP2	physical	25332237
PSA3_YEAST	PRE9	genetic	25332237
PSA7_YEAST	PRE10	genetic	25332237
CSG2_YEAST	CSG2	genetic	27708008
SAC3_YEAST	SAC3	genetic	27708008
UME6_YEAST	UME6	genetic	27708008
RLA4_YEAST	RPP2B	genetic	27708008
RTF1_YEAST	RTF1	genetic	27708008
MET28_YEAST	MET28	genetic	27708008
VPS53_YEAST	VPS53	genetic	27708008
SDHX_YEAST	YJL045W	genetic	27708008
MRX5_YEAST	YJL147C	genetic	27708008
SNA3_YEAST	SNA3	genetic	27708008
CSN12_YEAST	YJR084W	genetic	27708008
POC3_YEAST	IRC25	genetic	27708008
RL22A_YEAST	RPL22A	genetic	27708008
POC4_YEAST	POC4	genetic	27708008
ATG41_YEAST	ICY2	genetic	27708008
NAA30_YEAST	MAK3	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FUB1_YEAST

Related Literatures of Post-Translational Modification