| UniProt ID | ARD1_YEAST | |
|---|---|---|
| UniProt AC | P07347 | |
| Protein Name | N-terminal acetyltransferase A complex catalytic subunit ARD1 | |
| Gene Name | ARD1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 238 | |
| Subcellular Localization | Cytoplasm . | |
| Protein Description | Catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover.. | |
| Protein Sequence | MPINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDCEDSDEQDENDKLELTLDGTNDGRTIKLDPTYLAPGEKLVGYVLVKMNDDPDQQNEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQISNFTHRRLKENEEKLEDDLESDLLEDIIKQGVNDIIV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 80 | Acetylation | TNDGRTIKLDPTYLA CCCCCEEEECCCCCC | 46.34 | 24489116 | |
| 91 | Ubiquitination | TYLAPGEKLVGYVLV CCCCCCCEEEEEEEE | 55.15 | 24961812 | |
| 191 | Acetylation | GEDAYAMKKVLKLEE CCCHHHHHHHHHHHH | 31.40 | 24489116 | |
| 195 | Acetylation | YAMKKVLKLEELQIS HHHHHHHHHHHHHCC | 57.76 | 24489116 | |
| 222 | Phosphorylation | KLEDDLESDLLEDII HHHHHHHHHHHHHHH | 40.64 | 22369663 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ARD1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ARD1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ARD1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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