dbPTM

PEX8_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PEX8_YEAST
UniProt AC	P53248
Protein Name	Peroxisomal biogenesis factor 8
Gene Name	PEX8
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	589
Subcellular Localization	Peroxisome matrix .
Protein Description	Required for peroxisome assembly..
Protein Sequence	MFDHDVEYLITALSSETRIQYDQRLLDEIAANVVYYVPRVKSPDTLYRLVGALFRSQFIVQLPPLRLLHIVKDVFLWKLEVSEPTLPISKFYLVWNAVFESHRATWNLSQLMVLDGVLVTYPSFKQLNNAYFIDESSNKTALYYRNWKLQLFSPIWAQLWNTAIVRANLSIQHCLLIALALLFNQSNRSALLHGVDVSWNLVTEKLLDLLEEYVHGIVQPMEIFSTDSVLSTNLNHLASCLTSSITRSNEATLVNSVRKLERICRYLSDTVASLKEQQLDFKFQNVFILIILALKELSAMNMTILPNHKDTFYSMICLSLFHVHVLTQKIGTVGFPSYDYVYDNLVTYFIVMDDLSKITTVLELMKRNNTKQDPNKLVFYINFLNKITNYYGCRIRLPFITEFIEPLLHFDVFFSGKTGNTLDIEIKESIHTLTITVLSIDSSYSSQVAQWQVSRILVYLKMSMDQFIAGKLSANQILLIFGHLSTQLPSLHNYNKHLLRDSLHETYIRIVNVKNPEKKNVLIECLIVQIAFINNPHHLIGWLNICLQLINTHNKKLLQQLWEMVSSLESSLAIDWWYTTVLSSQSSKL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
514	Ubiquitination	YIRIVNVKNPEKKNV EEEEEECCCHHHCCH	62.67	23749301

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PEX8_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PEX8_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PEX8_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PEX14_YEAST	PEX14	physical	12667447
PEX2_YEAST	PEX2	physical	12667447
PEX12_YEAST	PEX12	physical	12667447
PEX13_YEAST	PEX13	physical	12667447
PEX17_YEAST	PEX17	physical	12667447
PEX5_YEAST	PEX5	physical	12667447
PEX5_YEAST	PEX5	physical	10652355
PEX7_YEAST	PEX7	physical	20655618
PEX12_YEAST	PEX12	genetic	23891562
ICE2_YEAST	ICE2	genetic	23891562
APC11_YEAST	APC11	genetic	27708008
RPN5_YEAST	RPN5	genetic	27708008
CDC1_YEAST	CDC1	genetic	27708008
GPI11_YEAST	GPI11	genetic	27708008
CDC12_YEAST	CDC12	genetic	27708008
CFT2_YEAST	CFT2	genetic	27708008
DBP9_YEAST	DBP9	genetic	27708008
LST8_YEAST	LST8	genetic	27708008
TIM23_YEAST	TIM23	genetic	27708008
TIM50_YEAST	TIM50	genetic	27708008
SWD1_YEAST	SWD1	genetic	27708008
ODPB_YEAST	PDB1	genetic	27708008
TXTP_YEAST	CTP1	genetic	27708008
THRC_YEAST	THR4	genetic	27708008
NHP10_YEAST	NHP10	genetic	27708008
BRE1_YEAST	BRE1	genetic	27708008
THI3_YEAST	THI3	genetic	27708008
RV167_YEAST	RVS167	genetic	27708008
ODPA_YEAST	PDA1	genetic	27708008
RTF1_YEAST	RTF1	genetic	27708008
NPR3_YEAST	NPR3	genetic	27708008
IXR1_YEAST	IXR1	genetic	27708008
RS21A_YEAST	RPS21A	genetic	27708008
VPS13_YEAST	VPS13	genetic	27708008
BRE2_YEAST	BRE2	genetic	27708008
UPS1_YEAST	UPS1	genetic	27708008
PET8_YEAST	PET8	genetic	27708008
ODP2_YEAST	LAT1	genetic	27708008
VPS17_YEAST	VPS17	genetic	27708008
PMA2_YEAST	PMA2	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PEX8_YEAST

Related Literatures of Post-Translational Modification