| UniProt ID | DBP9_YEAST | |
|---|---|---|
| UniProt AC | Q06218 | |
| Protein Name | ATP-dependent RNA helicase DBP9 | |
| Gene Name | DBP9 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 594 | |
| Subcellular Localization | Nucleus, nucleolus . | |
| Protein Description | ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.. | |
| Protein Sequence | MSYEKKSVEGAYIDDSTTFEAFHLDSRLLQAIKNIGFQYPTLIQSHAIPLALQQKRDIIAKAATGSGKTLAYLIPVIETILEYKKTIDNGEENGTLGIILVPTRELAQQVYNVLEKLVLYCSKDIRTLNISSDMSDSVLSTLLMDQPEIIVGTPGKLLDLLQTKINSISLNELKFLVVDEVDLVLTFGYQDDLNKIGEYLPLKKNLQTFLMSATLNDDIQALKQKFCRSPAILKFNDEEINKNQNKLLQYYVKVSEFDKFLLCYVIFKLNLIKGKTLIFVNNIDRGYRLKLVMEQFGIKSCILNSELPVNSRQHIVDQFNKNVYQLLIATDDTEYIKEEDDEIEEGHNTENQEEKSLEGEPENDKKPSKKKKVQVKKDKEYGVSRGVDFKNVACVLNFDLPTTAKSYVHRVGRTARGGKTGTAISFVVPLKEFGKHKPSMLQTAKKDERILSRIIKQQSKLGLELQPYKFDQKQVEAFRYRMEDGFRAVTQVAIREARVKELKQELLASEKLKRHFEENPKELQSLRHDKELHPARVQQHLKRVPDYLLPESARGNGTKVKFVPFHNAKKRHSHKKGRVSKPKNGKVDPLKNFK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 123 | Acetylation | KLVLYCSKDIRTLNI HHHHHHCCCCCCCCC | 54.32 | 24489116 | |
| 164 | Acetylation | LLDLLQTKINSISLN HHHHHHHHHHCCCHH | 27.25 | 24489116 | |
| 229 | Phosphorylation | LKQKFCRSPAILKFN HHHHHCCCCHHHHCC | 21.62 | 21551504 | |
| 234 | Acetylation | CRSPAILKFNDEEIN CCCCHHHHCCHHHHH | 35.69 | 24489116 | |
| 246 | Acetylation | EINKNQNKLLQYYVK HHHHHHHHHHHHHHH | 40.59 | 24489116 | |
| 300 | Phosphorylation | MEQFGIKSCILNSEL HHHHCCCCCCCCCCC | 12.41 | 25882841 | |
| 305 | Phosphorylation | IKSCILNSELPVNSR CCCCCCCCCCCCCCC | 36.74 | 25882841 | |
| 324 | Phosphorylation | DQFNKNVYQLLIATD HHCCHHHHHEEEECC | 11.66 | 28132839 | |
| 349 | Phosphorylation | EIEEGHNTENQEEKS CHHCCCCCCCHHHHH | 30.55 | 28889911 | |
| 356 | Phosphorylation | TENQEEKSLEGEPEN CCCHHHHHCCCCCCC | 34.63 | 25521595 | |
| 390 | Ubiquitination | VSRGVDFKNVACVLN CCCCCCCCCEEEEEE | 46.15 | 17644757 | |
| 390 | Acetylation | VSRGVDFKNVACVLN CCCCCCCCCEEEEEE | 46.15 | 24489116 | |
| 405 | Ubiquitination | FDLPTTAKSYVHRVG CCCCCCHHHHHHHCC | 39.98 | 17644757 | |
| 419 | Ubiquitination | GRTARGGKTGTAISF CCCCCCCCCCCEEEE | 46.75 | 17644757 | |
| 431 | Ubiquitination | ISFVVPLKEFGKHKP EEEEEEHHHHCCCCC | 44.95 | 17644757 | |
| 435 | Ubiquitination | VPLKEFGKHKPSMLQ EEHHHHCCCCCHHHH | 54.50 | 17644757 | |
| 469 | Acetylation | GLELQPYKFDQKQVE CCEECCCCCCHHHHH | 49.50 | 24489116 | |
| 473 | Acetylation | QPYKFDQKQVEAFRY CCCCCCHHHHHHHHH | 59.15 | 24489116 | |
| 503 | Acetylation | EARVKELKQELLASE HHHHHHHHHHHHHHH | 42.70 | 24489116 | |
| 521 | Acetylation | RHFEENPKELQSLRH HHHHHCHHHHHHHHC | 80.69 | 24489116 | |
| 542 | Acetylation | ARVQQHLKRVPDYLL HHHHHHHHCCCCCCC | 49.58 | 25381059 | |
| 561 | Acetylation | RGNGTKVKFVPFHNA CCCCCEEEEEECCCC | 42.05 | 25381059 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of DBP9_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of DBP9_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of DBP9_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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