MRH4_YEAST - dbPTM
MRH4_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MRH4_YEAST
UniProt AC P53166
Protein Name ATP-dependent RNA helicase MRH4, mitochondrial
Gene Name MRH4
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 561
Subcellular Localization Mitochondrion .
Protein Description ATP-binding RNA helicase involved in mitochondrial RNA metabolism. Required for maintenance of mitochondrial DNA..
Protein Sequence MSLFFKPVISPQWSFPVLLKIGVRSYAGGPRTKHKGNSPLASVPTGSSNKNRKQKAKGKKGNKKNDPDQAFNFGEYGGLKKDVEMNMDSTNKLIQKISNFDQLLILPPVRDAVKEIISKESLKLQDSRKKTSENIIPSPIQTVAIKRISKNLMDPKLQIHAIAAETGSGKTMAYLIPLIDYLKRQELETPELWETLRKNVLIRSIILVPTHELVDQVYETVSKTKTLLGLNSFKWDKATSYRDLLENIKNRIDILVTTPGKLLNLFSIRMITRPDKVLSKVGFVVLDEADTLLDRSWLEETHSAIKRIPNINHLIFCSATIPQEFNKTMQRLFPTVVPIMTPRLHKLPFALDFKVINSALSPFKGSKIKALAQTLYAISNDDTEPGFEKRCIIFVNEKKNVPEIVNLLNKKFGHNAIGLTGEDTFEERSEKIMPFLSPPRPLSEVVAQSTSPPTSLKKFEIPDSNIVIGKLKNTNSNGTAPSNKSLHVLVTTDLMARGLNFKGVRNVVLYDVPKTSIDLIHRVGRTARMKQGGRVFMLTDSKTKSWAKALPKIIKKHQRLS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
25PhosphorylationLLKIGVRSYAGGPRT
EEEECCEECCCCCCC		19.5427017623
38PhosphorylationRTKHKGNSPLASVPT
CCCCCCCCCCCCCCC		29.9327017623
45PhosphorylationSPLASVPTGSSNKNR
CCCCCCCCCCCCHHH		47.7628889911
48PhosphorylationASVPTGSSNKNRKQK
CCCCCCCCCHHHHHH		53.8427017623
149PhosphorylationTVAIKRISKNLMDPK
HHHHHHHHHHCCCCC		21.3719795423
257PhosphorylationNRIDILVTTPGKLLN
HCCCEEEECCHHHHH		24.6727017623
258PhosphorylationRIDILVTTPGKLLNL
CCCEEEECCHHHHHH		23.6727017623
328PhosphorylationIPQEFNKTMQRLFPT
CCHHHHHHHHHHCCC		21.4619823750
335PhosphorylationTMQRLFPTVVPIMTP
HHHHHCCCCCCCCCC		27.1419823750
341PhosphorylationPTVVPIMTPRLHKLP
CCCCCCCCCCCCCCC		13.1319823750
361PhosphorylationKVINSALSPFKGSKI
EEHHHHCCCCCCHHH		28.1827214570
541PhosphorylationRVFMLTDSKTKSWAK
EEEEEECCCCHHHHH		36.6727017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MRH4_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MRH4_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MRH4_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RRP8_YEASTRRP8genetic
19061648
LRP1_YEASTLRP1genetic
19061648
EIF3J_YEASTHCR1genetic
19061648
RS8A_YEASTRPS8Agenetic
19061648
RS8B_YEASTRPS8Agenetic
19061648
NMD5_YEASTNMD5genetic
19061648
HSP71_YEASTSSA1physical
19536198
MRH4_YEASTMRH4physical
22940862
HSP71_YEASTSSA1physical
22940862
RM40_YEASTMRPL40physical
24206665
SGT1_YEASTSGT1genetic
27708008
MAK5_YEASTMAK5genetic
27708008
TAF5_YEASTTAF5genetic
27708008
AME1_YEASTAME1genetic
27708008
DPOD_YEASTPOL3genetic
27708008
NSE4_YEASTNSE4genetic
27708008
TIM22_YEASTTIM22genetic
27708008
SLU7_YEASTSLU7genetic
27708008
RMRP_YEASTSNM1genetic
27708008
SLD5_YEASTSLD5genetic
27708008
PRP31_YEASTPRP31genetic
27708008
MED6_YEASTMED6genetic
27708008
NNF1_YEASTNNF1genetic
27708008
DBP6_YEASTDBP6genetic
27708008
RU1A_YEASTMUD1genetic
27708008
SDHX_YEASTYJL045Wgenetic
27708008
PIR1_YEASTPIR1genetic
27708008
PFKA2_YEASTPFK2genetic
27708008
TOM70_YEASTTOM70genetic
27708008
IRA2_YEASTIRA2genetic
27708008
INO4_YEASTINO4genetic
27708008
PDE2_YEASTPDE2genetic
27708008
MS116_YEASTMSS116physical
28520979
DSS1_YEASTDSS1physical
28520979
SUV3_YEASTSUV3physical
28520979
MRM1_YEASTMRM1physical
28520979
MTG1_YEASTMTG1physical
28520979
IMG1_YEASTIMG1physical
28520979
MNP1_YEASTMNP1physical
28520979
RM02_YEASTMRP7physical
28520979
RM09_YEASTMRPL9physical
28520979
RM16_YEASTMRPL16physical
28520979
RM32_YEASTMRPL32physical
28520979
RM07_YEASTMRPL7physical
28520979
RM35_YEASTMRPL35physical
28520979
RM22_YEASTMRPL22physical
28520979
RM15_YEASTMRPL15physical
28520979
RM17_YEASTMRPL17physical
28520979
RM28_YEASTMRPL28physical
28520979
RT28_YEASTMRPS28physical
28520979
RT22_YEASTRSM22physical
28520979
RT07_YEASTRSM7physical
28520979
RT13_YEASTMRP13physical
28520979
RTPT_YEASTPET123physical
28520979
RT31_YEASTYMR31physical
28520979
OXA1_YEASTOXA1physical
28520979
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MRH4_YEAST

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Related Literatures of Post-Translational Modification

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