| UniProt ID | MS116_YEAST | |
|---|---|---|
| UniProt AC | P15424 | |
| Protein Name | ATP-dependent RNA helicase MSS116, mitochondrial | |
| Gene Name | MSS116 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 664 | |
| Subcellular Localization | Mitochondrion matrix . | |
| Protein Description | ATP-dependent RNA helicase required for mitochondrial splicing of group I and II introns. Specifically involved in the ATP-dependent splicing of the bl1 intron of COB. Also required for efficient mitochondrial translation.. | |
| Protein Sequence | MLTSILIKGRTPVLASRNLLAALSNCNHITWAVSRRLYNDGNRDQRNFGRNQRNNNSNRYRNSRFNSRPRTRSREDDDEVHFDKTTFSKLIHVPKEDNSKEVTLDSLLEEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVVISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSILKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGRTARSGKEGSSVLFICKDELPFVRELEDAKNIVIAKQEKYEPSEEIKSEVLEAVTEEPEDISDIVISLISSYRSCIKEYRFSERRILPEIASTYGVLLNDPQLKIPVSRRFLDKLGLSRSPIGKAMFEIRDYSSRDGNNKSYDYDDDSEISFRGNKNYNNRSQNRDYDDEPFRRSNNNRRSFSRSNDKNNYSSRNSNIY | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 84 | Acetylation | DDEVHFDKTTFSKLI CCCCEECCCCCHHHC | 48.82 | 24489116 | |
| 100 | Acetylation | VPKEDNSKEVTLDSL CCCCCCCCEECHHHH | 63.56 | 24489116 | |
| 136 | Phosphorylation | LTPVQQKTIKPILSS CCCCCCCCCCCCCCC | 29.87 | 22369663 | |
| 138 | Acetylation | PVQQKTIKPILSSED CCCCCCCCCCCCCCC | 31.10 | 24489116 | |
| 142 | Phosphorylation | KTIKPILSSEDHDVI CCCCCCCCCCCCCEE | 32.19 | 22369663 | |
| 143 | Phosphorylation | TIKPILSSEDHDVIA CCCCCCCCCCCCEEE | 43.53 | 22369663 | |
| 233 | Acetylation | AAMNKMNKLRPNIVI HHHHHHHCCCCCEEE | 42.23 | 24489116 | |
| 252 | Acetylation | RLIDVLEKYSNKFFR HHHHHHHHHCCCHHH | 50.22 | 24489116 | |
| 263 | Phosphorylation | KFFRFVDYKVLDEAD CHHHHCCHHHHHHHH | 9.55 | 28889911 | |
| 345 | Phosphorylation | AHERIDQSVVISEKF HHHHCCCHHHHCHHH | 18.01 | 29734811 | |
| 349 | Phosphorylation | IDQSVVISEKFANSI CCCHHHHCHHHHHHH | 24.11 | 29734811 | |
| 495 | Acetylation | VRELEDAKNIVIAKQ CEEHHHHHCEEEEEC | 60.57 | 24489116 | |
| 579 | Acetylation | VSRRFLDKLGLSRSP CCHHHHHHHCCCCCC | 46.75 | 22865919 | |
| 613 | Phosphorylation | SYDYDDDSEISFRGN CCCCCCCCCEEECCC | 43.77 | 21440633 | |
| 616 | Phosphorylation | YDDDSEISFRGNKNY CCCCCCEEECCCCCC | 12.58 | 28889911 | |
| 640 | Phosphorylation | DDEPFRRSNNNRRSF CCCCCCCCCCCCCCC | 39.39 | 25882841 | |
| 661 | Phosphorylation | NNYSSRNSNIY---- CCCCCCCCCCC---- | 24.40 | 21440633 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MS116_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MS116_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MS116_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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