| UniProt ID | PIR1_YEAST | |
|---|---|---|
| UniProt AC | Q03178 | |
| Protein Name | Cell wall mannoprotein PIR1 | |
| Gene Name | PIR1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 341 | |
| Subcellular Localization | Secreted, cell wall . Covalently attached to the cell wall. | |
| Protein Description | Component of the outer cell wall layer. Required for stability of the cell wall and for optimal growth. Required for resistance against several antifungal and cell wall-perturbing agents and for tolerance to heat shock.. | |
| Protein Sequence | MQYKKSLVASALVATSLAAYAPKDPWSTLTPSATYKGGITDYSSTFGIAVEPIATTASSKAKRAAAISQIGDGQIQATTKTTAAAVSQIGDGQIQATTKTKAAAVSQIGDGQIQATTKTTSAKTTAAAVSQIGDGQIQATTKTKAAAVSQIGDGQIQATTKTTAAAVSQIGDGQIQATTKTTAAAVSQIGDGQIQATTNTTVAPVSQITDGQIQATTLTSATIIPSPAPAPITNGTDPVTAETCKSSGTLEMNLKGGILTDGKGRIGSIVANRQFQFDGPPPQAGAIYAAGWSITPEGNLAIGDQDTFYQCLSGNFYNLYDEHIGTQCNAVHLQAIDLLNC | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 6 | Phosphorylation | --MQYKKSLVASALV --CCCCHHHHHHHHH | 24.75 | 22890988 | |
| 10 | Phosphorylation | YKKSLVASALVATSL CCHHHHHHHHHHHHH | 18.04 | 22890988 | |
| 15 | Phosphorylation | VASALVATSLAAYAP HHHHHHHHHHHHHCC | 19.45 | 22890988 | |
| 16 | Phosphorylation | ASALVATSLAAYAPK HHHHHHHHHHHHCCC | 13.28 | 22890988 | |
| 20 | Phosphorylation | VATSLAAYAPKDPWS HHHHHHHHCCCCCCC | 20.16 | 22890988 | |
| 27 | Phosphorylation | YAPKDPWSTLTPSAT HCCCCCCCCCCCCCE | 20.94 | 22890988 | |
| 28 | Phosphorylation | APKDPWSTLTPSATY CCCCCCCCCCCCCEE | 30.68 | 22890988 | |
| 30 | Phosphorylation | KDPWSTLTPSATYKG CCCCCCCCCCCEECC | 18.45 | 22890988 | |
| 32 | Phosphorylation | PWSTLTPSATYKGGI CCCCCCCCCEECCCC | 28.18 | 22890988 | |
| 34 | Phosphorylation | STLTPSATYKGGITD CCCCCCCEECCCCCC | 30.06 | 22890988 | |
| 35 | Phosphorylation | TLTPSATYKGGITDY CCCCCCEECCCCCCC | 13.83 | 22890988 | |
| 268 | Phosphorylation | DGKGRIGSIVANRQF CCCCCEEEEEECCEE | 16.12 | 25752575 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PIR1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PIR1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PIR1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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