DSS1_YEAST - dbPTM
DSS1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DSS1_YEAST
UniProt AC P39112
Protein Name Exoribonuclease II, mitochondrial
Gene Name DSS1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 969
Subcellular Localization Mitochondrion matrix .
Protein Description Essential for mitochondrial biogenesis.; Required for intron-independent turnover and processing of mitochondrial RNA. Participates in 3' mtRNA processing where it hydrolyzes single-stranded RNA or partially double-stranded RNA with 3' single-stranded tails..
Protein Sequence MVVRRKVHVLLIARSFHSYTPCFRVTTRGKRQRSKSKQQAKVELDHTRELDNDQATETVVDRSVGPEKDIESINKDFLQRTKGLEPDIELKQLPQIKQEFNQRYKDRYVKPSEDWYVNSWRSLTKPKIPLYKLINSDFQLITKLKAPNPMEFQPVQLMESPLNVGDFVLLKMRPNELAMCVSLPSSTMDPRYTFVTIDGTMCFATKNRVLLRIPHKLPAGIHSLIQPESHHKHLPIGTVKNFSNQTNILPIVARQLITSRYPAQISKLAWKDLPITTKKLQLLHRSLQNYMGPWQIPFFTLVGLVQKLDLNKALDDKNGINYLTSLVNNYHTVNDIPINSPTFVSTYWAIMQQQESNLWGEIHLNTALLSPISVTIIPLKSQHLYYAQVIEKLEANSYREVNKFVKLVNERKYRDISALYPSVIQLLKDFAAGNFHNNGIIVALISKIFRKIERYKDCDITRDICQDLINEITPNSIPNPLLLNMDLALPASSKLVKWQQKLYDLTNIEELQWKKSGTDDDRYDFGDLRVFCIDSETAHEIDDGVSVKNYGRDGLYTLYIHIADPTSMFPESTNVDIEGISTDILNVALKRSFTTYLPDTVVPMLPQSICHLSDLGKQGQRTKTISFSVDVKITSKCSGKSIEIMYDSFKIRKGIVSNFPKATYEDVDRILGTPNSEASPVKKDLESLSMISKLLREQRIKNSNAVIFGEGFNKGLVMLNADSEGELTEVTFSDQEETLSTILVSEMMILANTLTGRYFAENKIGGVFRCYKQLPLGEVAQQQYDSMITSTKKGIFPKLKDIVKLSSLLNSSFYTGRPFRHEMIGAKQYLTVTSPLRRFPDLINHLQIHRHLQKKPLCFNQTQIDSLIWPIQSRADILKRASRNSSTYWTLNYLKKLTKLEPERTFDVMVTSVPQNGFTGCVFPDLSFARGTLKLHPSSMHYPMIGDIVKNCKISKIDCLEGMLELEKL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
258PhosphorylationIVARQLITSRYPAQI
HHHHHHHHCCCCHHH		18.7521126336
259PhosphorylationVARQLITSRYPAQIS
HHHHHHHCCCCHHHH		23.8721126336
398PhosphorylationEKLEANSYREVNKFV
HHHHCCCHHHHHHHH		15.5925371407
689PhosphorylationKKDLESLSMISKLLR
HHHHHHHHHHHHHHH		24.2928889911
692PhosphorylationLESLSMISKLLREQR
HHHHHHHHHHHHHHH		14.4928889911
771PhosphorylationIGGVFRCYKQLPLGE
CCCEEEEEECCCHHH		9.4928889911
784PhosphorylationGEVAQQQYDSMITST
HHHHHHHHHHHHHHH		12.9728889911
786PhosphorylationVAQQQYDSMITSTKK
HHHHHHHHHHHHHCC		13.7228889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DSS1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DSS1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DSS1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PT127_YEASTPET127genetic
10397341
IF2M_YEASTIFM1genetic
19061648
AEP3_YEASTAEP3genetic
19061648
GAL1_YEASTGAL1genetic
19269370
RPA14_YEASTRPA14genetic
19269370
PFKA1_YEASTPFK1genetic
19269370
SCH9_YEASTSCH9genetic
19269370
SIP4_YEASTSIP4genetic
19269370
PBS2_YEASTPBS2genetic
19269370
RPA34_YEASTRPA34genetic
19269370
YMR1_YEASTYMR1genetic
19269370
MUD2_YEASTMUD2genetic
19269370
SSK1_YEASTSSK1genetic
19269370
CTL1_YEASTCTL1genetic
19269370
OCA1_YEASTOCA1genetic
19269370
INP52_YEASTINP52genetic
19269370
SSU72_YEASTSSU72genetic
19269370
BNI4_YEASTBNI4genetic
19269370
KCC2_YEASTCMK2genetic
19269370
INP53_YEASTINP53genetic
19269370
CG12_YEASTCLN2genetic
19269370
SUV3_YEASTSUV3physical
21911497
RPN3_YEASTRPN3physical
18775730
BUD31_YEASTBUD31genetic
27708008
STE13_YEASTSTE13genetic
27708008
SNC2_YEASTSNC2genetic
27708008
LCL1_YEASTLCL1genetic
27708008
MRX4_YEASTYPL168Wgenetic
27708008
WDR6_YEASTRTT10genetic
27708008
RBG1_YEASTRBG1genetic
27708008
GEM1_YEASTGEM1genetic
27708008
QRI7_YEASTQRI7genetic
27708008
INV2_YEASTSUC2genetic
27708008
YJU6_YEASTYJL206Cgenetic
27708008
LDB18_YEASTLDB18genetic
27708008
IZH3_YEASTIZH3genetic
27708008
PUR91_YEASTADE16genetic
27708008
SRN2_YEASTSRN2genetic
27708008
SWS2_YEASTSWS2genetic
27708008
NBA1_YEASTNBA1genetic
27708008
IRA2_YEASTIRA2genetic
27708008
RUD3_YEASTRUD3genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DSS1_YEAST

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Related Literatures of Post-Translational Modification

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