UniProt ID | BNI4_YEAST | |
---|---|---|
UniProt AC | P53858 | |
Protein Name | Protein BNI4 | |
Gene Name | BNI4 | |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
Sequence Length | 892 | |
Subcellular Localization | ||
Protein Description | ||
Protein Sequence | MSDSISDSKSSELLNSTFYSSTSINTLDHARTFRNSLILKEISDQSLNSSIKPCESVLDRDVESSVLQRSFGESNARDSEVQTVNMTTSPSLSALADILNERSKYADQKTRKAQNIESSIIEEEEEAEEQNNSINYHEDITGSRLSVREEANENLAMTSPNLIDIDGSNSIQVAPLSLPSFEEPDFLSTPRVKPDSQGPRSKVSTRRTILERDNNLPVKREENTIINSETESTTHSAPFLKEDPKPSPPSSKLYNPKVRLNKAEARKYTDSSAQRTTSAGSVLEDTSMHKKKKSIFSFLKKKEPKPVIGNNSVTNEKNKMSSSSTFSMNIQTSLKTPEKLKKKSHSSSSIFNSFLKGKIETSDSPRKEPMRQKKRTPKSKDKKQDTEQIIDAASVLSTESPLLRKNHDDTPVKIDHVTRSIDQRKPTPLNMDLILGGDKQINTPLQEHVREDDDAKNDLQLPTKDNFLSLDYEAPSPAFSKHDTGEVLFPKFLDNHEVDSIVSLERTRSTKSNKRSSMNSQRRSLTDTLSIKAQSEGMFITEASSVVLSTPDLTKSPASSILKNGRFEYSDNFSREHSYEGTTNEDFLDIKDDSGPLKKDDIFLESIEQKFDQLVMASDEEKTEVERDVPKPREEPLKKDSERQSVFADDDNELISDIMEFASFINFGDDDLNLDLDLGDTTASYATETPEPVGNDEVNRSGTFDTRNNKEDSYKERETQSYSAAGATTYGDERQGQLHTFEQDGSEINDNEFENEDFNKHIEQPIEVTPRNNAYLPEFEPNRPVSMSFKGLKAPRMNTSFIDSMTPDSPVKSDLTSLGEVYVNSNNDQGVRFSSQIILYDTYGEFEYDRHPEISTCNQLTPQLAQMIKLELNELKSAMEVHDDSRCYTHFY | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
2 | Phosphorylation | ------MSDSISDSK ------CCCCCCCCH | 39.81 | 30377154 | |
4 | Phosphorylation | ----MSDSISDSKSS ----CCCCCCCCHHH | 19.38 | 27717283 | |
6 | Phosphorylation | --MSDSISDSKSSEL --CCCCCCCCHHHHH | 39.52 | 30377154 | |
8 | Phosphorylation | MSDSISDSKSSELLN CCCCCCCCHHHHHHH | 27.87 | 30377154 | |
16 | Phosphorylation | KSSELLNSTFYSSTS HHHHHHHHCCCCCCC | 21.62 | 22369663 | |
17 | Phosphorylation | SSELLNSTFYSSTSI HHHHHHHCCCCCCCC | 26.06 | 22369663 | |
19 | Phosphorylation | ELLNSTFYSSTSINT HHHHHCCCCCCCCCH | 11.20 | 22369663 | |
20 | Phosphorylation | LLNSTFYSSTSINTL HHHHCCCCCCCCCHH | 23.97 | 22369663 | |
21 | Phosphorylation | LNSTFYSSTSINTLD HHHCCCCCCCCCHHH | 18.13 | 22369663 | |
22 | Phosphorylation | NSTFYSSTSINTLDH HHCCCCCCCCCHHHH | 27.90 | 22369663 | |
23 | Phosphorylation | STFYSSTSINTLDHA HCCCCCCCCCHHHHH | 18.78 | 22369663 | |
26 | Phosphorylation | YSSTSINTLDHARTF CCCCCCCHHHHHHHH | 31.71 | 22369663 | |
32 | Phosphorylation | NTLDHARTFRNSLIL CHHHHHHHHHHHHHH | 27.94 | 22369663 | |
36 | Phosphorylation | HARTFRNSLILKEIS HHHHHHHHHHHHHCC | 16.72 | 22369663 | |
43 | Phosphorylation | SLILKEISDQSLNSS HHHHHHCCCCCCCCC | 30.59 | 28889911 | |
46 | Phosphorylation | LKEISDQSLNSSIKP HHHCCCCCCCCCCCC | 34.21 | 28889911 | |
49 | Phosphorylation | ISDQSLNSSIKPCES CCCCCCCCCCCCCHH | 38.44 | 19779198 | |
50 | Phosphorylation | SDQSLNSSIKPCESV CCCCCCCCCCCCHHH | 33.29 | 19779198 | |
64 | Phosphorylation | VLDRDVESSVLQRSF HHCHHHHHHHHHHHH | 26.12 | 28132839 | |
70 | Phosphorylation | ESSVLQRSFGESNAR HHHHHHHHHCCCCCC | 25.33 | 22369663 | |
79 | Phosphorylation | GESNARDSEVQTVNM CCCCCCCCCCEEEEC | 33.83 | 30377154 | |
83 | Phosphorylation | ARDSEVQTVNMTTSP CCCCCCEEEECCCCH | 21.01 | 28132839 | |
87 | Phosphorylation | EVQTVNMTTSPSLSA CCEEEECCCCHHHHH | 20.93 | 28132839 | |
88 | Phosphorylation | VQTVNMTTSPSLSAL CEEEECCCCHHHHHH | 28.07 | 28132839 | |
89 | Phosphorylation | QTVNMTTSPSLSALA EEEECCCCHHHHHHH | 11.88 | 28132839 | |
91 | Phosphorylation | VNMTTSPSLSALADI EECCCCHHHHHHHHH | 34.42 | 29650682 | |
93 | Phosphorylation | MTTSPSLSALADILN CCCCHHHHHHHHHHH | 26.10 | 21440633 | |
104 | Acetylation | DILNERSKYADQKTR HHHHHHHHHHHHHHH | 51.16 | 25381059 | |
109 | Acetylation | RSKYADQKTRKAQNI HHHHHHHHHHHHHHH | 51.34 | 25381059 | |
110 | Phosphorylation | SKYADQKTRKAQNIE HHHHHHHHHHHHHHH | 31.59 | 28889911 | |
118 | Phosphorylation | RKAQNIESSIIEEEE HHHHHHHHHHHHHHH | 24.04 | 22369663 | |
119 | Phosphorylation | KAQNIESSIIEEEEE HHHHHHHHHHHHHHH | 18.13 | 22369663 | |
133 | Phosphorylation | EAEEQNNSINYHEDI HHHHHHCCCCCCCCC | 21.54 | 22369663 | |
136 | Phosphorylation | EQNNSINYHEDITGS HHHCCCCCCCCCCCC | 12.62 | 22369663 | |
141 | Phosphorylation | INYHEDITGSRLSVR CCCCCCCCCCCCCHH | 41.23 | 19779198 | |
143 | Phosphorylation | YHEDITGSRLSVREE CCCCCCCCCCCHHHH | 22.77 | 22369663 | |
180 | Phosphorylation | VAPLSLPSFEEPDFL EECCCCCCCCCCCCC | 51.05 | 28889911 | |
196 | Phosphorylation | TPRVKPDSQGPRSKV CCCCCCCCCCCCCCC | 45.63 | 23749301 | |
224 | Phosphorylation | PVKREENTIINSETE CCCCCCCCEEECCCC | 26.89 | 22369663 | |
228 | Phosphorylation | EENTIINSETESTTH CCCCEEECCCCCCCC | 35.17 | 22369663 | |
230 | Phosphorylation | NTIINSETESTTHSA CCEEECCCCCCCCCC | 34.75 | 22369663 | |
232 | Phosphorylation | IINSETESTTHSAPF EEECCCCCCCCCCCC | 46.13 | 21440633 | |
233 | Phosphorylation | INSETESTTHSAPFL EECCCCCCCCCCCCC | 23.46 | 22369663 | |
234 | Phosphorylation | NSETESTTHSAPFLK ECCCCCCCCCCCCCC | 24.10 | 22369663 | |
236 | Phosphorylation | ETESTTHSAPFLKED CCCCCCCCCCCCCCC | 35.23 | 22369663 | |
247 | Phosphorylation | LKEDPKPSPPSSKLY CCCCCCCCCCCHHCC | 56.41 | 25752575 | |
250 | Phosphorylation | DPKPSPPSSKLYNPK CCCCCCCCHHCCCCC | 43.41 | 29734811 | |
251 | Phosphorylation | PKPSPPSSKLYNPKV CCCCCCCHHCCCCCC | 32.24 | 24961812 | |
268 | Phosphorylation | NKAEARKYTDSSAQR CHHHHHHCCCCCCCH | 15.38 | 19823750 | |
269 | Phosphorylation | KAEARKYTDSSAQRT HHHHHHCCCCCCCHH | 32.23 | 19823750 | |
271 | Phosphorylation | EARKYTDSSAQRTTS HHHHCCCCCCCHHCC | 21.55 | 21440633 | |
272 | Phosphorylation | ARKYTDSSAQRTTSA HHHCCCCCCCHHCCC | 31.09 | 19823750 | |
276 | Phosphorylation | TDSSAQRTTSAGSVL CCCCCCHHCCCCCHH | 17.02 | 22369663 | |
277 | Phosphorylation | DSSAQRTTSAGSVLE CCCCCHHCCCCCHHH | 20.83 | 20377248 | |
278 | Phosphorylation | SSAQRTTSAGSVLED CCCCHHCCCCCHHHC | 29.98 | 22369663 | |
281 | Phosphorylation | QRTTSAGSVLEDTSM CHHCCCCCHHHCCCC | 24.20 | 22369663 | |
286 | Phosphorylation | AGSVLEDTSMHKKKK CCCHHHCCCCHHCHH | 20.69 | 22369663 | |
287 | Phosphorylation | GSVLEDTSMHKKKKS CCHHHCCCCHHCHHH | 31.07 | 22369663 | |
293 | Acetylation | TSMHKKKKSIFSFLK CCCHHCHHHHHHHHH | 58.63 | 24489116 | |
294 | Phosphorylation | SMHKKKKSIFSFLKK CCHHCHHHHHHHHHC | 37.43 | 21440633 | |
297 | Phosphorylation | KKKKSIFSFLKKKEP HCHHHHHHHHHCCCC | 28.18 | 21440633 | |
305 | Acetylation | FLKKKEPKPVIGNNS HHHCCCCCCCCCCCC | 53.67 | 25381059 | |
312 | Phosphorylation | KPVIGNNSVTNEKNK CCCCCCCCCCCCCCC | 34.03 | 27717283 | |
314 | Phosphorylation | VIGNNSVTNEKNKMS CCCCCCCCCCCCCCC | 37.16 | 27717283 | |
321 | Phosphorylation | TNEKNKMSSSSTFSM CCCCCCCCCCCEEEE | 28.78 | 28889911 | |
322 | Phosphorylation | NEKNKMSSSSTFSMN CCCCCCCCCCEEEEE | 25.47 | 28889911 | |
323 | Phosphorylation | EKNKMSSSSTFSMNI CCCCCCCCCEEEEEH | 26.54 | 28889911 | |
324 | Phosphorylation | KNKMSSSSTFSMNIQ CCCCCCCCEEEEEHH | 35.11 | 28889911 | |
325 | Phosphorylation | NKMSSSSTFSMNIQT CCCCCCCEEEEEHHH | 22.98 | 28889911 | |
327 | Phosphorylation | MSSSSTFSMNIQTSL CCCCCEEEEEHHHCC | 15.82 | 28889911 | |
332 | Phosphorylation | TFSMNIQTSLKTPEK EEEEEHHHCCCCHHH | 32.03 | 28889911 | |
333 | Phosphorylation | FSMNIQTSLKTPEKL EEEEHHHCCCCHHHH | 16.11 | 28889911 | |
336 | Phosphorylation | NIQTSLKTPEKLKKK EHHHCCCCHHHHHHC | 41.81 | 28889911 | |
344 | Phosphorylation | PEKLKKKSHSSSSIF HHHHHHCCCCCHHHH | 37.16 | 22369663 | |
346 | Phosphorylation | KLKKKSHSSSSIFNS HHHHCCCCCHHHHHH | 38.72 | 22369663 | |
347 | Phosphorylation | LKKKSHSSSSIFNSF HHHCCCCCHHHHHHH | 23.76 | 22369663 | |
348 | Phosphorylation | KKKSHSSSSIFNSFL HHCCCCCHHHHHHHH | 30.39 | 22369663 | |
349 | Phosphorylation | KKSHSSSSIFNSFLK HCCCCCHHHHHHHHC | 32.90 | 22369663 | |
353 | Phosphorylation | SSSSIFNSFLKGKIE CCHHHHHHHHCCCCC | 22.62 | 22369663 | |
362 | Phosphorylation | LKGKIETSDSPRKEP HCCCCCCCCCCCCCC | 24.25 | 19779198 | |
364 | Phosphorylation | GKIETSDSPRKEPMR CCCCCCCCCCCCCCC | 26.77 | 25521595 | |
386 | Phosphorylation | SKDKKQDTEQIIDAA CCCCCCCHHHHHHHH | 27.56 | 22369663 | |
394 | Phosphorylation | EQIIDAASVLSTESP HHHHHHHHHHCCCCC | 25.88 | 20377248 | |
397 | Phosphorylation | IDAASVLSTESPLLR HHHHHHHCCCCCHHH | 28.15 | 25521595 | |
398 | Phosphorylation | DAASVLSTESPLLRK HHHHHHCCCCCHHHC | 36.00 | 20377248 | |
400 | Phosphorylation | ASVLSTESPLLRKNH HHHHCCCCCHHHCCC | 22.42 | 22369663 | |
410 | Phosphorylation | LRKNHDDTPVKIDHV HHCCCCCCCCCCCEE | 35.72 | 28889911 | |
413 | Ubiquitination | NHDDTPVKIDHVTRS CCCCCCCCCCEECCC | 43.55 | 23749301 | |
443 | Phosphorylation | GGDKQINTPLQEHVR CCCCCCCCCHHHHCC | 27.31 | 21440633 | |
469 | Phosphorylation | PTKDNFLSLDYEAPS CCCCCCCCCCCCCCC | 18.30 | 23607784 | |
472 | Phosphorylation | DNFLSLDYEAPSPAF CCCCCCCCCCCCCCC | 21.20 | 23607784 | |
476 | Phosphorylation | SLDYEAPSPAFSKHD CCCCCCCCCCCCCCC | 35.59 | 22369663 | |
480 | Phosphorylation | EAPSPAFSKHDTGEV CCCCCCCCCCCCCCE | 31.05 | 21440633 | |
484 | Phosphorylation | PAFSKHDTGEVLFPK CCCCCCCCCCEECHH | 34.65 | 23607784 | |
500 | Phosphorylation | LDNHEVDSIVSLERT CCCCCCCEEEEEEEC | 30.02 | 22369663 | |
503 | Phosphorylation | HEVDSIVSLERTRST CCCCEEEEEEECCCC | 23.89 | 22369663 | |
507 | Phosphorylation | SIVSLERTRSTKSNK EEEEEEECCCCCCCC | 21.42 | 21440633 | |
509 | Phosphorylation | VSLERTRSTKSNKRS EEEEECCCCCCCCCH | 39.30 | 20377248 | |
510 | Phosphorylation | SLERTRSTKSNKRSS EEEECCCCCCCCCHH | 34.89 | 21440633 | |
516 | Phosphorylation | STKSNKRSSMNSQRR CCCCCCCHHCHHHHC | 35.23 | 24961812 | |
517 | Phosphorylation | TKSNKRSSMNSQRRS CCCCCCHHCHHHHCH | 26.47 | 19823750 | |
520 | Phosphorylation | NKRSSMNSQRRSLTD CCCHHCHHHHCHHHH | 19.20 | 24961812 | |
524 | Phosphorylation | SMNSQRRSLTDTLSI HCHHHHCHHHHHHHH | 37.50 | 22369663 | |
526 | Phosphorylation | NSQRRSLTDTLSIKA HHHHCHHHHHHHHEE | 28.34 | 22369663 | |
528 | Phosphorylation | QRRSLTDTLSIKAQS HHCHHHHHHHHEEEC | 19.71 | 22369663 | |
530 | Phosphorylation | RSLTDTLSIKAQSEG CHHHHHHHHEEECCC | 24.92 | 24930733 | |
556 | Phosphorylation | STPDLTKSPASSILK CCCCCCCCCHHHHHH | 22.06 | 21440633 | |
559 | Phosphorylation | DLTKSPASSILKNGR CCCCCCHHHHHHCCC | 22.69 | 21440633 | |
560 | Phosphorylation | LTKSPASSILKNGRF CCCCCHHHHHHCCCE | 33.76 | 21440633 | |
570 | Phosphorylation | KNGRFEYSDNFSREH HCCCEECCCCCCCCC | 20.91 | 28889911 | |
574 | Phosphorylation | FEYSDNFSREHSYEG EECCCCCCCCCCCCC | 42.91 | 22369663 | |
578 | Phosphorylation | DNFSREHSYEGTTNE CCCCCCCCCCCCCCC | 21.81 | 22369663 | |
579 | Phosphorylation | NFSREHSYEGTTNED CCCCCCCCCCCCCCC | 21.93 | 22369663 | |
582 | Phosphorylation | REHSYEGTTNEDFLD CCCCCCCCCCCCCCC | 17.95 | 22369663 | |
583 | Phosphorylation | EHSYEGTTNEDFLDI CCCCCCCCCCCCCCC | 47.68 | 19795423 | |
594 | Phosphorylation | FLDIKDDSGPLKKDD CCCCCCCCCCCCHHH | 53.06 | 22369663 | |
618 | Phosphorylation | FDQLVMASDEEKTEV HHHHHCCCHHHHCHH | 27.71 | 22369663 | |
623 | Phosphorylation | MASDEEKTEVERDVP CCCHHHHCHHCCCCC | 48.84 | 28889911 | |
689 | Phosphorylation | TASYATETPEPVGND CCCCCCCCCCCCCCC | 28.70 | 28889911 | |
701 | Phosphorylation | GNDEVNRSGTFDTRN CCCCCCCCCCCCCCC | 36.66 | 28889911 | |
703 | Phosphorylation | DEVNRSGTFDTRNNK CCCCCCCCCCCCCCC | 21.42 | 25752575 | |
719 | Phosphorylation | DSYKERETQSYSAAG CCHHHHHCCCCCCCC | 29.09 | 23749301 | |
721 | Phosphorylation | YKERETQSYSAAGAT HHHHHCCCCCCCCCE | 28.60 | 28889911 | |
722 | Phosphorylation | KERETQSYSAAGATT HHHHCCCCCCCCCEE | 7.78 | 27017623 | |
723 | Phosphorylation | ERETQSYSAAGATTY HHHCCCCCCCCCEEC | 19.52 | 19779198 | |
740 | Phosphorylation | ERQGQLHTFEQDGSE CCCCEEEEEECCCCC | 37.14 | 22369663 | |
746 | Phosphorylation | HTFEQDGSEINDNEF EEEECCCCCCCCCCC | 43.52 | 22369663 | |
769 | Phosphorylation | IEQPIEVTPRNNAYL CCCCCEECCCCCCCC | 12.07 | 17563356 | |
786 | Phosphorylation | FEPNRPVSMSFKGLK CCCCCCCCCCCCCCC | 16.05 | 21440633 | |
788 | Phosphorylation | PNRPVSMSFKGLKAP CCCCCCCCCCCCCCC | 19.12 | 28152593 | |
799 | Phosphorylation | LKAPRMNTSFIDSMT CCCCCCCCCCHHCCC | 18.70 | 22890988 | |
800 | Phosphorylation | KAPRMNTSFIDSMTP CCCCCCCCCHHCCCC | 18.39 | 22890988 | |
804 | Phosphorylation | MNTSFIDSMTPDSPV CCCCCHHCCCCCCCC | 21.53 | 22890988 | |
806 | Phosphorylation | TSFIDSMTPDSPVKS CCCHHCCCCCCCCCC | 28.09 | 22890988 | |
809 | Phosphorylation | IDSMTPDSPVKSDLT HHCCCCCCCCCCCCC | 32.56 | 22369663 | |
813 | Phosphorylation | TPDSPVKSDLTSLGE CCCCCCCCCCCCCCE | 37.78 | 22369663 | |
816 | Phosphorylation | SPVKSDLTSLGEVYV CCCCCCCCCCCEEEE | 27.22 | 22369663 | |
817 | Phosphorylation | PVKSDLTSLGEVYVN CCCCCCCCCCEEEEC | 41.49 | 22369663 | |
822 | Phosphorylation | LTSLGEVYVNSNNDQ CCCCCEEEECCCCCC | 6.93 | 22369663 | |
825 | Phosphorylation | LGEVYVNSNNDQGVR CCEEEECCCCCCCCE | 27.28 | 22369663 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of BNI4_YEAST !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of BNI4_YEAST !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of BNI4_YEAST !! |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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Phosphorylation | |
Reference | PubMed |
"A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-70; SER-180; SER-278;SER-397; SER-400; SER-476; SER-503; SER-618; THR-623; THR-689;THR-703; SER-721; SER-746; THR-769; SER-809; THR-816; SER-817 ANDSER-825, AND MASS SPECTROMETRY. | |
"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-503; SER-746 ANDTHR-769, AND MASS SPECTROMETRY. | |
"Analysis of phosphorylation sites on proteins from Saccharomycescerevisiae by electron transfer dissociation (ETD) massspectrometry."; Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.; Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-364, AND MASSSPECTROMETRY. | |
"Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae."; Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.; J. Proteome Res. 6:1190-1197(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-618, AND MASSSPECTROMETRY. |