ERFD_YEAST - dbPTM
ERFD_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ERFD_YEAST
UniProt AC P41912
Protein Name Ras modification protein ERF4
Gene Name SHR5
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 237
Subcellular Localization Endoplasmic reticulum membrane
Peripheral membrane protein .
Protein Description The ERF2-SHR5 complex is a palmitoyltransferase specific for Ras proteins. Palmitoylates RAS2, which is required for its proper plasma membrane localization..
Protein Sequence MCDSHQKEEDNANTSERALFFNYHEFSYSFYEDLGSEDAKPTEHDEDHKLCITHFPNVYAARGSAEFQVTRVVRVPRRFDESRSSLETPQFSTQLPGSEPAAIVGDDGTSFVRCGRYDIGDHVFGCSSVSPLSEYLSAAELAEVVHRVNGFLLREEGEVFGWRNLSGLLLDMLTGGLWSWVLGPLLSRPVFQESLALEQYVAQLNSPGGLLHERGVRLVLPRRSGCLSLDFVVPRPK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of ERFD_YEAST !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ERFD_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ERFD_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ERFD_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ERFB_YEASTERF2physical
12379641
RAS2_YEASTRAS2genetic
12379641
SSO2_YEASTSSO2genetic
16269340
STE14_YEASTSTE14genetic
16269340
MON2_YEASTMON2genetic
16269340
CTR2_YEASTCTR2genetic
16269340
CYB5_YEASTCYB5genetic
16269340
COPE_YEASTSEC28genetic
16269340
MTC4_YEASTMTC4genetic
16269340
SCS7_YEASTSCS7genetic
16269340
RIC1_YEASTRIC1genetic
16269340
UBC7_YEASTUBC7genetic
22904317
DOA10_YEASTSSM4genetic
22904317
RPN10_YEASTRPN10genetic
22904317
HRD1_YEASTHRD1genetic
22904317
ERFB_YEASTERF2genetic
22904317
SLX5_YEASTSLX5genetic
27708008
YL413_YEASTINA1genetic
27708008
SST2_YEASTSST2genetic
27708008
SSO2_YEASTSSO2genetic
27708008
OCA2_YEASTOCA2genetic
27708008
RAS2_YEASTRAS2genetic
27708008
SUCA_YEASTLSC1genetic
27708008
SRO7_YEASTSRO7genetic
27708008
SPEE_YEASTSPE3genetic
27708008
COG3_YEASTCOG3genetic
29674565
CCZ1_YEASTCCZ1genetic
29674565
TCPA_YEASTTCP1genetic
29674565
RPB7_YEASTRPB7genetic
29674565
RSP5_YEASTRSP5genetic
29674565
VPS24_YEASTVPS24genetic
29674565
MMS22_YEASTMMS22genetic
29674565
SCS7_YEASTSCS7genetic
29674565
ZDS1_YEASTZDS1genetic
29674565
LST8_YEASTLST8genetic
29674565
DPOZ_YEASTREV3genetic
29674565
SEC8_YEASTSEC8genetic
29674565
EKI1_YEASTEKI1genetic
29674565
MON1_YEASTMON1genetic
29674565
VAM7_YEASTVAM7genetic
29674565
SAC1_YEASTSAC1genetic
29674565
NMT_YEASTNMT1genetic
29674565
RL9B_YEASTRPL9Bgenetic
29674565
VPS5_YEASTVPS5genetic
29674565

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ERFD_YEAST

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Related Literatures of Post-Translational Modification

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