| UniProt ID | FET4_YEAST | |
|---|---|---|
| UniProt AC | P40988 | |
| Protein Name | Low-affinity Fe(2+) transport protein | |
| Gene Name | FET4 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 552 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein. |
|
| Protein Description | Required for Fe(2+) ion low affinity uptake.. | |
| Protein Sequence | MGKIAEFLGNPGARPDVHHRAPTVDCKQYEEFGDSNDYKNDDVVRVVSHSDESTDDELCNVNLTETGAIFTSKGFTGLSKGFTDKTLDFLVRVAGSQAVFFIVWIILIIWVVIGIVYNAPFNWQVVMQDGQSIQSYVWDTLLMRQQLMSTHEQILICGRLKSRLASFKNYLTRSTPEEEKADCTVEANEVSSVENHIDPSAINGELPVENWYDRLSNVASRYMGSIAAMVIFWIGIFVWIGCGAIPKDAGNTPPYTGETTGSNPRLKKFSDAWQMYINTAVAVSLLICTTFLQNIRARHDYFTGRFLVDIFDMDEKIDYRIRKHFNDFETPHPVVTIESKKRSTGRKMIDWYADIIGTGIGVLIGVAVFATWIGIGSPMKWDDNWWLIIGTYTGLIGFLDGFVLREVYFRIVQHEEKNYSDVAKEDLELFQELGIECPEEFSGKAPEINTIGYRTSQYINRICSTPWSVLVSVIIIIGLICIASGLRWSTTGQLIANTPTMIIEEFFLLVLLQAHNWADRQRRVEVTALYARRRILLSYVEKRFPEVMMLEK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 35 | Phosphorylation | QYEEFGDSNDYKNDD HHHHHCCCCCCCCCC | 31.79 | 25521595 | |
| 38 | Phosphorylation | EFGDSNDYKNDDVVR HHCCCCCCCCCCEEE | 18.88 | 25521595 | |
| 39 | Ubiquitination | FGDSNDYKNDDVVRV HCCCCCCCCCCEEEE | 57.68 | 23749301 | |
| 48 | Phosphorylation | DDVVRVVSHSDESTD CCEEEEEECCCCCCC | 17.89 | 20377248 | |
| 50 | Phosphorylation | VVRVVSHSDESTDDE EEEEEECCCCCCCCC | 35.25 | 20377248 | |
| 53 | Phosphorylation | VVSHSDESTDDELCN EEECCCCCCCCCCCC | 41.97 | 28889911 | |
| 54 | Phosphorylation | VSHSDESTDDELCNV EECCCCCCCCCCCCC | 45.48 | 20377248 | |
| 149 | Phosphorylation | LMRQQLMSTHEQILI HHHHHHHCCCHHHHH | 34.89 | 28889911 | |
| 150 | Phosphorylation | MRQQLMSTHEQILIC HHHHHHCCCHHHHHH | 18.57 | 28889911 | |
| 174 | Phosphorylation | FKNYLTRSTPEEEKA HHHHHHCCCCHHHHC | 42.98 | 19779198 | |
| 175 | Phosphorylation | KNYLTRSTPEEEKAD HHHHHCCCCHHHHCC | 31.28 | 19779198 | |
| 180 | Ubiquitination | RSTPEEEKADCTVEA CCCCHHHHCCCEEEC | 53.45 | 23749301 | |
| 184 | Phosphorylation | EEEKADCTVEANEVS HHHHCCCEEECCCCC | 23.17 | 19779198 | |
| 191 | Phosphorylation | TVEANEVSSVENHID EEECCCCCCCCCCCC | 23.61 | 23749301 | |
| 323 | Ubiquitination | KIDYRIRKHFNDFET HHCHHHHHHCCCCCC | 50.61 | 17644757 | |
| 340 | Ubiquitination | PVVTIESKKRSTGRK CEEEEEECCCCCCCH | 39.14 | 17644757 | |
| 341 | Ubiquitination | VVTIESKKRSTGRKM EEEEEECCCCCCCHH | 61.94 | 17644757 | |
| 539 | Phosphorylation | RRRILLSYVEKRFPE HHHHHHHHHHHHCCH | 16.76 | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of FET4_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of FET4_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of FET4_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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