YMR1_YEAST - dbPTM
YMR1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID YMR1_YEAST
UniProt AC P47147
Protein Name Phosphoinositide 3-phosphatase
Gene Name YMR1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 688
Subcellular Localization Cytoplasm .
Protein Description Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P). Involved in the control of PI3P-dependent signaling and in the maintenance of endosomal system integrity..
Protein Sequence MEYIKIAKVSNVVLHRRGTATQGTLHLTTHHLIFESPQLSTEFWFPYPLIYGVHKNPGSTLLSKLTSTNQIQLEGTDSQNYKLYQGKDLWSFVNIKVIGKDYAVFSLDFGGDLHLQARKVYDSILNLTVLSNITQLYAFIYISNNLERKLPSPDSWDIYDPIKEFRRQGLDSKDETCPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQPLPGLINQRSIQDEKLVWESFNSFCNKDIRRTKHVIVDARPRTNALAQMALGGGTENMDNYNFFLADNNMGVDKSLKLPTVTRLFLGIDNIHIVSNTAAYMTEVICQGGDLNLPLEQNLIRSQKFSNWLKLNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHLNSDIRFHDNTMHSNFNDVDTNGDDLDIGVNTQDDYAEDDEGGEDETNLINLSRISKKFNENFKLNKKSLKFVSPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVYHLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYFRSRRKQFINPNFIQRKRSGMNEHDQNLEEEEKVEWISPDLKKVQWWWQLYGRKDSEMNDELRHKRDSVPISVDKKSKEHSNSDGGKGLNLSIFGFDMFNRK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
82UbiquitinationGTDSQNYKLYQGKDL
CCCCCCEEEECCCCC		48.5523749301
152PhosphorylationNLERKLPSPDSWDIY
CHHHCCCCCCCCCCC		52.3428889911
155PhosphorylationRKLPSPDSWDIYDPI
HCCCCCCCCCCCHHH		29.9928889911
173UbiquitinationRRQGLDSKDETCPWR
HHCCCCCCCCCCCCC		60.2923749301
203PhosphorylationSKLFVPRSTSDILLK
CCCCCCCCHHHHHHH		26.6230377154
378PhosphorylationLNTLILKSVDMLLKS
HHHHHHHHHHHHHHH		21.6527214570
642PhosphorylationQLYGRKDSEMNDELR
HHHCCCCHHHCHHHH		41.6030377154
654PhosphorylationELRHKRDSVPISVDK
HHHHCCCCCCCCCCC		33.5519823750
658PhosphorylationKRDSVPISVDKKSKE
CCCCCCCCCCCCCCC		20.4228889911
663PhosphorylationPISVDKKSKEHSNSD
CCCCCCCCCCCCCCC		49.3628889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of YMR1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of YMR1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of YMR1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MED14_YEASTRGR1physical
11805837
INP52_YEASTINP52genetic
15169871
KPC1_YEASTPKC1genetic
16306222
SAC7_YEASTSAC7genetic
16306222
MSG5_YEASTMSG5genetic
16306222
OSH7_YEASTOSH7genetic
16306222
YPT1_YEASTYPT1genetic
16306222
VAM6_YEASTVAM6genetic
16306222
ROY1_YEASTROY1genetic
16306222
ARF3_YEASTARF3genetic
16306222
RME1_YEASTRME1genetic
16306222
AZF1_YEASTAZF1genetic
16306222
ATG21_YEASTATG21genetic
16306222
ELP4_YEASTELP4genetic
16306222
SCS2_YEASTSCS2genetic
16306222
GLO3_YEASTGLO3genetic
16306222
HMRA1_YEASTHMRA1genetic
16306222
SSB1_YEASTSSB1genetic
16306222
RAS2_YEASTRAS2genetic
19269370
ERB1_YEASTERB1physical
20489023
GCN2_YEASTGCN2physical
20489023
NOC2_YEASTNOC2physical
20489023
NOC3_YEASTNOC3physical
20489023
NUG1_YEASTNUG1physical
20489023
PSH1_YEASTPSH1physical
20489023
RPB2_YEASTRPB2physical
20489023
RPB1_YEASTRPO21physical
20489023
VPS35_YEASTVPS35physical
20489023
VPS5_YEASTVPS5physical
20489023
INP52_YEASTINP52genetic
16306222
INP53_YEASTINP53genetic
16306222
BECN1_YEASTVPS30genetic
16306222
ROM2_YEASTROM2genetic
16306222
TOR1_YEASTTOR1genetic
21127252
BCK1_YEASTBCK1genetic
21127252
UME6_YEASTUME6genetic
21127252
CALM_YEASTCMD1genetic
27708008
RPB1_YEASTRPO21genetic
27708008
RPN5_YEASTRPN5genetic
27708008
RRP1_YEASTRRP1genetic
27708008
MED6_YEASTMED6genetic
27708008
PRI2_YEASTPRI2genetic
27708008
PRS7_YEASTRPT1genetic
27708008
MCM1_YEASTMCM1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of YMR1_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-654, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory