| UniProt ID | RRP1_YEAST | |
|---|---|---|
| UniProt AC | P35178 | |
| Protein Name | Ribosomal RNA-processing protein 1 | |
| Gene Name | RRP1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 278 | |
| Subcellular Localization | Nucleus, nucleolus. | |
| Protein Description | Required for 27S rRNA processing to 25S and 5.8S.. | |
| Protein Sequence | METSNFVKQLSSNNRKTRVNALEALKKYLTAKQFKENKQIEFNKLWKGLYYAMWFSDRPRPQQRLANELGELHGLYFDPKDNSTADELTTNDKAFIKFSRGFWKVMCFEWFNIDRYRLDKYLLLIRRVLFSQLKYLQSRNWDKKLVDEYIKKVLRWLPLSGSPKVYTGIPIHIVDILLDEWERLLKDGDEDDEDEENKEEEMRKIAESAKKTPLADVIAIFQDIVADYNNSKVLREKIKEDLFSDTRLVSWDILEGETQHNDSSNESEEEEEEEWKGF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------METSNFVK -------CCCHHHHH | 13.15 | 22814378 | |
| 3 | Phosphorylation | -----METSNFVKQL -----CCCHHHHHHH | 27.89 | 30377154 | |
| 4 | Phosphorylation | ----METSNFVKQLS ----CCCHHHHHHHH | 18.24 | 30377154 | |
| 11 | Phosphorylation | SNFVKQLSSNNRKTR HHHHHHHHCCCHHHH | 28.64 | 30377154 | |
| 12 | Phosphorylation | NFVKQLSSNNRKTRV HHHHHHHCCCHHHHH | 46.87 | 30377154 | |
| 26 | Acetylation | VNALEALKKYLTAKQ HHHHHHHHHHHHHHH | 46.55 | 24489116 | |
| 44 | Acetylation | NKQIEFNKLWKGLYY CCCHHHHHHHHHHHH | 62.13 | 24489116 | |
| 80 | Acetylation | HGLYFDPKDNSTADE CCCCCCCCCCCCCCC | 71.97 | 24489116 | |
| 84 | Phosphorylation | FDPKDNSTADELTTN CCCCCCCCCCCCCCC | 44.37 | 27214570 | |
| 93 | Acetylation | DELTTNDKAFIKFSR CCCCCCCHHHHHCCC | 47.46 | 24489116 | |
| 97 | Acetylation | TNDKAFIKFSRGFWK CCCHHHHHCCCCHHH | 30.73 | 24489116 | |
| 237 | Acetylation | NSKVLREKIKEDLFS CCHHHHHHHHHHHCC | 53.28 | 24489116 | |
| 239 | Acetylation | KVLREKIKEDLFSDT HHHHHHHHHHHCCCC | 57.13 | 24489116 | |
| 244 | Phosphorylation | KIKEDLFSDTRLVSW HHHHHHCCCCEEEEE | 45.42 | 24961812 | |
| 246 | Phosphorylation | KEDLFSDTRLVSWDI HHHHCCCCEEEEEHH | 25.38 | 24961812 | |
| 250 | Phosphorylation | FSDTRLVSWDILEGE CCCCEEEEEHHHHCC | 24.51 | 19795423 | |
| 258 | Phosphorylation | WDILEGETQHNDSSN EHHHHCCCCCCCCCC | 46.08 | 28889911 | |
| 263 | Phosphorylation | GETQHNDSSNESEEE CCCCCCCCCCCCHHH | 40.14 | 17330950 | |
| 264 | Phosphorylation | ETQHNDSSNESEEEE CCCCCCCCCCCHHHH | 47.70 | 17330950 | |
| 267 | Phosphorylation | HNDSSNESEEEEEEE CCCCCCCCHHHHHHH | 55.34 | 17330950 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RRP1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RRP1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RRP1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae."; Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.; J. Proteome Res. 6:1190-1197(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-267, AND MASSSPECTROMETRY. | |
