MRS3_YEAST - dbPTM
MRS3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MRS3_YEAST
UniProt AC P10566
Protein Name Mitochondrial RNA-splicing protein MRS3
Gene Name MRS3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 314
Subcellular Localization Mitochondrion inner membrane
Multi-pass membrane protein.
Protein Description MRS3 suppresses a mitochondrial splice defect in the first intron of the COB gene. It may act as a carrier, exerting its suppressor activity via modulation of solute concentrations in the mitochondrion (possibly of cations)..
Protein Sequence MVENSSSNNSTRPIPAIPMDLPDYEALPTHAPLYHQLIAGAFAGIMEHSVMFPIDALKTRIQSANAKSLSAKNMLSQISHISTSEGTLALWKGVQSVILGAGPAHAVYFGTYEFCKKNLIDSSDTQTHHPFKTAISGACATTASDALMNPFDTIKQRIQLNTSASVWQTTKQIYQSEGLAAFYYSYPTTLVMNIPFAAFNFVIYESSTKFLNPSNEYNPLIHCLCGSISGSTCAAITTPLDCIKTVLQIRGSQTVSLEIMRKADTFSKAASAIYQVYGWKGFWRGWKPRIVANMPATAISWTAYECAKHFLMTY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
171UbiquitinationASVWQTTKQIYQSEG
HHHHHHHHHHHHHCC		37.7817644757
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MRS3_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MRS3_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MRS3_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
FRDA_YEASTYFH1genetic
15767258
FRDA_YEASTYFH1genetic
16769722
MRS4_YEASTMRS4genetic
16511496
MRS4_YEASTMRS4genetic
19285482
RV167_YEASTRVS167genetic
20093466
MRS4_YEASTMRS4genetic
20093466
NST1_YEASTNST1genetic
20093466
CCC1_YEASTCCC1genetic
20139087
FRA1_YEASTFRA1genetic
20139087
RIM2_YEASTRIM2genetic
20139087
RIM2_YEASTRIM2genetic
21115478
RIM2_YEASTRIM2genetic
21777202
MRS4_YEASTMRS4genetic
23800229
RIM2_YEASTRIM2genetic
23800229
MRS4_YEASTMRS4genetic
24624902
CCC1_YEASTCCC1genetic
24798331
CSN12_YEASTYJR084Wgenetic
27708008
MRS4_YEASTMRS4genetic
27708008
RNP1_YEASTRNP1genetic
27708008
ENV10_YEASTENV10genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MRS3_YEAST

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Related Literatures of Post-Translational Modification

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