TPP1_YEAST - dbPTM
TPP1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TPP1_YEAST
UniProt AC Q03796
Protein Name Polynucleotide 3'-phosphatase
Gene Name TPP1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 238
Subcellular Localization Nucleus .
Protein Description Dephosphorylate DNA's 3'-phosphate termini. Has a role in the repair of breaks in single-stranded DNA..
Protein Sequence MSHKLTILPFLIKFTPKFPQSIDHDEHGLNVYAFDLDHTIIKPKSPNISFSRSASDWQFINFNSKKSTLDYLCNIIDNDPTAVIVIFSNQGGVITVPRTSKSCTKYTNKILLFLKAIKNDERGETLSHRLWLYAAPKRPKTFAANHSKITFASLGESYNNDPNIFEKVRKPMTGMVEFFKRDLESAYRVSEQISPIKLNWIYYCGDAAGRKKDFSDSDIKFAENLHVEFKYPEEIFHG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
49PhosphorylationKPKSPNISFSRSASD
CCCCCCCCCCCCCCC		24.6530377154
55PhosphorylationISFSRSASDWQFINF
CCCCCCCCCCEEEEC		40.4030377154
106PhosphorylationTSKSCTKYTNKILLF
CCCCCCHHHHHHHHH		9.4419795423
107PhosphorylationSKSCTKYTNKILLFL
CCCCCHHHHHHHHHH		31.4319795423
148AcetylationTFAANHSKITFASLG
CEECCCCCEEEEECH		37.9124489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TPP1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TPP1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TPP1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RAD52_YEASTRAD52genetic
11585902
SPT4_YEASTSPT4genetic
17314980
PP11_YEASTSIT4genetic
19269370
FAB1_YEASTFAB1genetic
19269370
MNN11_YEASTMNN11genetic
19269370
PUR92_YEASTADE17genetic
19269370
CG11_YEASTCLN1genetic
19269370
APN2_YEASTAPN2genetic
11585902
APN1_YEASTAPN1genetic
11585902
APTX_YEASTHNT3genetic
20399152
APN2_YEASTAPN2genetic
12783866
RAD1_YEASTRAD1genetic
12783866
RAD1_YEASTRAD1genetic
15687272
CHK1_YEASTCHK1genetic
15687272
RAD9_YEASTRAD9genetic
15687272
DUN1_YEASTDUN1genetic
15687272
SML1_YEASTSML1genetic
15687272
RAD17_YEASTRAD17genetic
15687272
MEC3_YEASTMEC3genetic
15687272
DDC1_YEASTDDC1genetic
15687272
RAD24_YEASTRAD24genetic
15687272
RAD53_YEASTRAD53genetic
15687272
RT107_YEASTRTT107genetic
15687272
TOF1_YEASTTOF1genetic
15687272
MRC1_YEASTMRC1genetic
15687272
MAD2_YEASTMAD2genetic
15687272
SECU_YEASTPDS1genetic
15687272
UNG_YEASTUNG1genetic
15687272
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TPP1_YEAST

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Related Literatures of Post-Translational Modification

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