IGD1_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IGD1_YEAST
• UniProt AC: P43598
• Protein Name: Inhibitor of glycogen debranching 1
• Gene Name: IGD1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 195
• Subcellular Localization: Cytoplasm .
• Protein Description: Acts as an inhibitor of GDB1, enhancing the ability of cells to store glucose as glycogen..
• Protein Sequence: MTDPHLNTPQVSTSPTFERSQDFLNIDEPPCAQETPSVSTFNLPGPSAPAQSVDKPVPMIRRRSTNYMDALNSREQARERESSIGEHAPGAERRSSGPMDFQNTIHNMQYRTTNDSDLSHAGVDMGDSISHTPICSRAGNRPIFKNSYLDNNSNGNSARVPHGSPPQLGTRRKSSFKYEDFKKDIYNQLHMFGEK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTDPHLNTP ------CCCCCCCCC		30377154
8	Phosphorylation	MTDPHLNTPQVSTSP CCCCCCCCCCCCCCC		24909858
12	Phosphorylation	HLNTPQVSTSPTFER CCCCCCCCCCCCCCC		22369663
13	Phosphorylation	LNTPQVSTSPTFERS CCCCCCCCCCCCCCC		22369663
14	Phosphorylation	NTPQVSTSPTFERSQ CCCCCCCCCCCCCCC		22369663
16	Phosphorylation	PQVSTSPTFERSQDF CCCCCCCCCCCCCCC		22369663
64	Phosphorylation	VPMIRRRSTNYMDAL CCCEECCCCCHHHHH		22369663
65	Phosphorylation	PMIRRRSTNYMDALN CCEECCCCCHHHHHH		22369663
67	Phosphorylation	IRRRSTNYMDALNSR EECCCCCHHHHHHHH		22369663
73	Phosphorylation	NYMDALNSREQARER CHHHHHHHHHHHHHH		22369663
82	Phosphorylation	EQARERESSIGEHAP HHHHHHHHHHCCCCC		22369663
83	Phosphorylation	QARERESSIGEHAPG HHHHHHHHHCCCCCC		22369663
95	Phosphorylation	APGAERRSSGPMDFQ CCCCCCCCCCCCCHH		22369663
96	Phosphorylation	PGAERRSSGPMDFQN CCCCCCCCCCCCHHH		22369663
104	Phosphorylation	GPMDFQNTIHNMQYR CCCCHHHHHHCCEEE		19779198
110	Phosphorylation	NTIHNMQYRTTNDSD HHHHCCEEECCCCHH		22369663
112	Phosphorylation	IHNMQYRTTNDSDLS HHCCEEECCCCHHHH		30377154
116	Phosphorylation	QYRTTNDSDLSHAGV EEECCCCHHHHHCCC		19779198
119	Phosphorylation	TTNDSDLSHAGVDMG CCCCHHHHHCCCCCC		19779198
128	Phosphorylation	AGVDMGDSISHTPIC CCCCCCCCCCCCCCC		23749301
130	Phosphorylation	VDMGDSISHTPICSR CCCCCCCCCCCCCCC		28889911
132	Phosphorylation	MGDSISHTPICSRAG CCCCCCCCCCCCCCC		28889911
136	Phosphorylation	ISHTPICSRAGNRPI CCCCCCCCCCCCCCC		26447709
145	Acetylation	AGNRPIFKNSYLDNN CCCCCCCCCCCCCCC		25381059
147	Phosphorylation	NRPIFKNSYLDNNSN CCCCCCCCCCCCCCC		22369663
153	Phosphorylation	NSYLDNNSNGNSARV CCCCCCCCCCCCCCC		22369663
157	Phosphorylation	DNNSNGNSARVPHGS CCCCCCCCCCCCCCC		21440633
164	Phosphorylation	SARVPHGSPPQLGTR CCCCCCCCCCCCCCC		22369663
170	Phosphorylation	GSPPQLGTRRKSSFK CCCCCCCCCCCCCCC		24961812
174	Phosphorylation	QLGTRRKSSFKYEDF CCCCCCCCCCCHHHH		22369663
175	Phosphorylation	LGTRRKSSFKYEDFK CCCCCCCCCCHHHHH		20377248
178	Phosphorylation	RRKSSFKYEDFKKDI CCCCCCCHHHHHHHH		22369663

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IGD1_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IGD1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IGD1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GDE_YEAST	GDB1	physical	16554755
BMH1_YEAST	BMH1	physical	16554755
GDE_YEAST	GDB1	physical	21585652
CDC1_YEAST	CDC1	genetic	27708008
SYG_YEAST	GRS1	genetic	27708008
PRP9_YEAST	PRP9	genetic	27708008
CDC37_YEAST	CDC37	genetic	27708008
GPI8_YEAST	GPI8	genetic	27708008
RMRP_YEAST	SNM1	genetic	27708008
ORC6_YEAST	ORC6	genetic	27708008
YHS2_YEAST	CIA2	genetic	27708008
CDC11_YEAST	CDC11	genetic	27708008
ORC1_YEAST	ORC1	genetic	27708008
NAB3_YEAST	NAB3	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.