UBX3_YEAST - dbPTM
UBX3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID UBX3_YEAST
UniProt AC Q12229
Protein Name UBX domain-containing protein 3
Gene Name UBX3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 455
Subcellular Localization Cytoplasm .
Protein Description Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway. Involved in delivery of substrates to the 26S proteasome. Also required for membrane fusion (By similarity)..
Protein Sequence MDIFRHTFGNNDDSFIRIPGAFREEPPADLNGRTEDQNSNTNEPTQSRDGRLKSILHFLFQAPLIVLYYLLNFIVRSSRLLKPLLRLHGFYQRKHNRLLDHSSQLHRLLENLENEAQAVTCSEGNGNNDDGSNTDSTSNNESSGVQFSFGSLYNPENGTFSKSIMQNSYTELLDACSEQVKFGVIYLHDPLLDNHMDYVNKILCSEAFVNMIRKYQVLLWYGDVTTSEGLQVSNALKIRQYPLLGIISLKAEKKIELIARVEGSISNYKAQDLEAIFSKNYSRLIQLRQQRQNIEMQRLIRQQQDSRYQDSLRRDQQRESERLEQTQREQMEREHQRIENQWLLWRKSQLKPEPSSDKDASKVAIRLENGQRLVRKFDASLPTEEIYAFVELQLHDMLNSENDTLPVYQPANYQHQYSFKLITPVPRRELDLSTKISDVSGIYPSGNIVMERLDE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
14PhosphorylationTFGNNDDSFIRIPGA
CCCCCCCCCEECCCC		25.9927214570
34PhosphorylationPADLNGRTEDQNSNT
CCCCCCCCCCCCCCC		45.3622890988
39PhosphorylationGRTEDQNSNTNEPTQ
CCCCCCCCCCCCCCC		39.1222890988
41PhosphorylationTEDQNSNTNEPTQSR
CCCCCCCCCCCCCCC		40.5622890988
169PhosphorylationKSIMQNSYTELLDAC
HHHHHCCHHHHHHHH		16.2828132839
215PhosphorylationFVNMIRKYQVLLWYG
HHHHHHHCCEEEEEC		8.2630377154
221PhosphorylationKYQVLLWYGDVTTSE
HCCEEEEECCEECCC		11.9230377154
225PhosphorylationLLWYGDVTTSEGLQV
EEEECCEECCCCEEC		29.3730377154
226PhosphorylationLWYGDVTTSEGLQVS
EEECCEECCCCEECC		25.3230377154
227PhosphorylationWYGDVTTSEGLQVSN
EECCEECCCCEECCC		21.9430377154
423PhosphorylationQYSFKLITPVPRREL
EEEEEEEECCCHHHC		28.7728889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of UBX3_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of UBX3_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of UBX3_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RER1_YEASTRER1genetic
16269340
PLMT_YEASTOPI3genetic
16269340
COPE_YEASTSEC28genetic
16269340
PGA3_YEASTPGA3genetic
16269340
RER1_YEASTRER1genetic
20093466
VPS60_YEASTVPS60genetic
20093466
MTO1_YEASTMTO1genetic
20093466
ARO8_YEASTARO8genetic
20093466
MED5_YEASTNUT1genetic
20093466
CYT2_YEASTCYT2genetic
20093466
VPS24_YEASTVPS24genetic
20093466
SRN2_YEASTSRN2genetic
20093466
FAR10_YEASTFAR10genetic
20093466
ATG17_YEASTATG17genetic
20093466
YM39_YEASTYMR166Cgenetic
20093466
NST1_YEASTNST1genetic
20093466
VPS27_YEASTVPS27genetic
20093466
COQ2_YEASTCOQ2genetic
20093466
BUB3_YEASTBUB3genetic
20093466
PNT1_YEASTPNT1genetic
20093466
HAP5_YEASTHAP5genetic
20093466
AP3D_YEASTAPL5genetic
20093466
MRX4_YEASTYPL168Wgenetic
20093466
SRO7_YEASTSRO7genetic
20093466
HSP71_YEASTSSA1physical
22940862
HSP72_YEASTSSA2physical
22940862
TUL1_YEASTTUL1physical
25078903
YO073_YEASTDSC2physical
25078903
YO223_YEASTDSC3physical
25078903
UBI4P_YEASTUBI4genetic
25078903
CDC48_YEASTCDC48physical
15258615
CLH_YEASTCHC1physical
26362318
CDC48_YEASTCDC48physical
26362318
TUL1_YEASTTUL1physical
26527740
YO223_YEASTDSC3physical
26527740
YO073_YEASTDSC2physical
26527740
CDC48_YEASTCDC48physical
26527740
LGE1_YEASTLGE1genetic
25183520
LGE1_YEASTLGE1physical
25183520
YO073_YEASTDSC2physical
29355480
YO223_YEASTDSC3physical
29355480
TUL1_YEASTTUL1physical
29355480
CDC48_YEASTCDC48physical
29355480
YIT4_YEASTYIR014Wphysical
29355480
YPR09_YEASTYPR109Wphysical
29355480
CSG2_YEASTCSG2genetic
29674565
LCB2_YEASTLCB2genetic
29674565
VPS60_YEASTVPS60genetic
29674565
COG3_YEASTCOG3genetic
29674565
ATC7_YEASTNEO1genetic
29674565
VPS24_YEASTVPS24genetic
29674565
SRN2_YEASTSRN2genetic
29674565
GAS1_YEASTGAS1genetic
29674565
ECM1_YEASTECM1genetic
29674565
RS6A_YEASTRPS6Bgenetic
29674565
RS6B_YEASTRPS6Bgenetic
29674565
PDC2_YEASTPDC2genetic
29674565
RRP8_YEASTRRP8genetic
29674565
SAC3_YEASTSAC3genetic
29674565
DBP3_YEASTDBP3genetic
29674565
TCD1_YEASTTCD1genetic
29674565
BTN1_YEASTYHC3genetic
29674565
ASF1_YEASTASF1genetic
29674565
CYP7_YEASTCPR7genetic
29674565
LAC1_YEASTLAC1genetic
29674565
ELM1_YEASTELM1genetic
29674565
PGM1_YEASTPGM1genetic
29674565
HBS1_YEASTHBS1genetic
29674565
FMP25_YEASTFMP25genetic
29674565
SSO2_YEASTSSO2genetic
29674565
ODP2_YEASTLAT1genetic
29674565
DYR_YEASTDFR1genetic
29674565
SCP1_YEASTSCP1genetic
29674565
ARL3_YEASTARL3genetic
29674565
ELP4_YEASTELP4genetic
29674565
NEW1_YEASTNEW1genetic
29674565
CGS5_YEASTCLB5genetic
29674565
HDA3_YEASTHDA3genetic
29674565
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of UBX3_YEAST

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Related Literatures of Post-Translational Modification

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