| UniProt ID | VPS60_YEAST | |
|---|---|---|
| UniProt AC | Q03390 | |
| Protein Name | Vacuolar protein-sorting-associated protein 60 | |
| Gene Name | VPS60 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 229 | |
| Subcellular Localization |
Endosome membrane Peripheral membrane protein. Vacuole membrane Peripheral membrane protein. |
|
| Protein Description | Has a role in a late stage of multivesicular body (MVB) formation. Can stimulate VPS4 ATPase activity via VTA1.. | |
| Protein Sequence | MNRIFGYGNKKSHDQLLQESNQSMNQAQQSLSNRISQLDTQIAQLNFQLQNIQKNLQRSNNKQPSLRKQALKILNKRKQLENMKDSLDSQSWSMTQAQLTNDNLQNTMITINALKQTNNAMKAQYGKINIDKLQDMQDEMLDLIEQGDELQEVLAMNNNSGELDDISDAELDAELDALAQEDFTLPTSENSLGNDMPSYLLGANAPPAFIDEEPNLDTEDKNKALESAQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 10 | Acetylation | RIFGYGNKKSHDQLL CCCCCCCCHHHHHHH | 51.82 | 25381059 | |
| 12 | Phosphorylation | FGYGNKKSHDQLLQE CCCCCCHHHHHHHHH | 33.63 | 22369663 | |
| 20 | Phosphorylation | HDQLLQESNQSMNQA HHHHHHHHHHHHHHH | 27.49 | 30377154 | |
| 23 | Phosphorylation | LLQESNQSMNQAQQS HHHHHHHHHHHHHHH | 24.77 | 23749301 | |
| 59 | Phosphorylation | IQKNLQRSNNKQPSL HHHHHHHCCCCCHHH | 31.62 | 27214570 | |
| 65 | Phosphorylation | RSNNKQPSLRKQALK HCCCCCHHHHHHHHH | 38.01 | 27214570 | |
| 122 | Ubiquitination | KQTNNAMKAQYGKIN HHHCHHHHHHHCCCC | 29.90 | 23749301 | |
| 127 | Ubiquitination | AMKAQYGKINIDKLQ HHHHHHCCCCHHHHH | 27.87 | 22817900 | |
| 127 | Acetylation | AMKAQYGKINIDKLQ HHHHHHCCCCHHHHH | 27.87 | 25381059 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of VPS60_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of VPS60_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of VPS60_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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