KTHY_YEAST - dbPTM
KTHY_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID KTHY_YEAST
UniProt AC P00572
Protein Name Thymidylate kinase
Gene Name CDC8
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 216
Subcellular Localization
Protein Description Catalyzes the conversion of dTMP to dTDP..
Protein Sequence MMGRGKLILIEGLDRTGKTTQCNILYKKLQPNCKLLKFPERSTRIGGLINEYLTDDSFQLSDQAIHLLFSANRWEIVDKIKKDLLEGKNIVMDRYVYSGVAYSAAKGTNGMDLDWCLQPDVGLLKPDLTLFLSTQDVDNNAEKSGFGDERYETVKFQEKVKQTFMKLLDKEIRKGDESITIVDVTNKGIQEVEALIWQIVEPVLSTHIDHDKFSFF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
27AcetylationTQCNILYKKLQPNCK
CHHHHHHHHCCCCCE
43.4922865919
155AcetylationDERYETVKFQEKVKQ
CCHHHHHHHHHHHHH
49.0724489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of KTHY_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of KTHY_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of KTHY_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PPN1_YEASTPPN1genetic
14764870
TSA2_YEASTTSA2genetic
14764870
HEH2_YEASTHEH2genetic
14764870
XRN1_YEASTXRN1genetic
14764870
STB5_YEASTSTB5genetic
14764870
PT191_YEASTPET191genetic
14764870
APN1_YEASTAPN1genetic
14764870
TOP3_YEASTTOP3genetic
14764870
SEC22_YEASTSEC22genetic
14764870
URE2_YEASTURE2genetic
14764870
G6PD_YEASTZWF1genetic
14764870
TRF5_YEASTTRF5genetic
14764870
KCY_YEASTURA6genetic
2549068
RAD51_YEASTRAD51genetic
45608
KTHY_YEASTCDC8physical
18719252
MNN10_YEASTMNN10genetic
19269370
NUP60_YEASTNUP60genetic
20093466
MRC1_YEASTMRC1genetic
20093466
CSM1_YEASTCSM1genetic
20093466
OCA4_YEASTOCA4genetic
20093466
GET3_YEASTGET3genetic
20093466
OCA6_YEASTOCA6genetic
20093466
DPB4_YEASTDPB4genetic
20093466
ARO1_YEASTARO1genetic
20093466
WDR59_YEASTMTC5genetic
20093466
SAC3_YEASTSAC3genetic
20093466
NBP2_YEASTNBP2genetic
20093466
RAD9_YEASTRAD9genetic
20093466
IPK1_YEASTIPK1genetic
20093466
SLX8_YEASTSLX8genetic
20093466
RAD24_YEASTRAD24genetic
20093466
VAM7_YEASTVAM7genetic
20093466
HOS2_YEASTHOS2genetic
20093466
AROC_YEASTARO2genetic
20093466
ITC1_YEASTITC1genetic
20093466
PIB2_YEASTPIB2genetic
20093466
RL24B_YEASTRPL24Bgenetic
20093466
MAL12_YEASTMAL12genetic
20093466
OCA5_YEASTOCA5genetic
20093466
PACC_YEASTRIM101genetic
20093466
VPS29_YEASTVPS29genetic
20093466
STB5_YEASTSTB5genetic
20093466
APN1_YEASTAPN1genetic
20093466
SET3_YEASTSET3genetic
20093466
ALAM_YEASTALT1genetic
20093466
MMR1_YEASTMMR1genetic
20093466
VIP1_YEASTVIP1genetic
20093466
SGS1_YEASTSGS1genetic
20093466
OCA1_YEASTOCA1genetic
20093466
BRE5_YEASTBRE5genetic
20093466
TRM11_YEASTTRM11genetic
20093466
PHO80_YEASTPHO80genetic
20093466
VAM10_YEASTVAM10genetic
20093466
ISW2_YEASTISW2genetic
20093466
RAD17_YEASTRAD17genetic
20093466
DDC1_YEASTDDC1genetic
20093466
RL21B_YEASTRPL21Bgenetic
20093466
LGE1_YEASTLGE1genetic
20093466
CDC14_YEASTCDC14physical
20489023
NET1_YEASTNET1physical
20489023
RRN9_YEASTRRN9physical
20489023
SIR2_YEASTSIR2physical
20489023
MMS4_YEASTMMS4genetic
14764870
MRC1_YEASTMRC1genetic
14764870
CSM1_YEASTCSM1genetic
14764870
THI74_YEASTTHI74genetic
14764870
ECM11_YEASTECM11genetic
14764870
PKH1_YEASTPKH1genetic
14764870
BCK2_YEASTBCK2genetic
14764870
RAD24_YEASTRAD24genetic
14764870
GET1_YEASTGET1genetic
14764870
IXR1_YEASTIXR1genetic
14764870
MTC2_YEASTMTC2genetic
14764870
FEN1_YEASTRAD27genetic
14764870
SGS1_YEASTSGS1genetic
14764870
CIK1_YEASTCIK1genetic
14764870
WRIP1_YEASTMGS1genetic
14764870
ISW2_YEASTISW2genetic
14764870
DDC1_YEASTDDC1genetic
14764870
FUMH_YEASTFUM1genetic
21623372
CSG2_YEASTCSG2genetic
21623372
ADH3_YEASTADH3genetic
21623372
ATP5E_YEASTATP15genetic
21623372
GGPPS_YEASTBTS1genetic
21623372
HTD2_YEASTHTD2genetic
21623372
TPS2_YEASTTPS2genetic
21623372
6PGD1_YEASTGND1genetic
21623372
ETR1_YEASTETR1genetic
21623372
ERG2_YEASTERG2genetic
21623372
CBF3B_YEASTCEP3genetic
27708008
BRE5_YEASTBRE5genetic
27708008
SGF29_YEASTSGF29genetic
27708008
IMG2_YEASTIMG2genetic
27708008
GST2_YEASTGTT2genetic
27708008
LSM7_YEASTLSM7genetic
27708008
SFL1_YEASTSFL1genetic
27708008
PDE2_YEASTPDE2genetic
27708008
THP3_YEASTTHP3genetic
27708008
KPYK1_YEASTCDC19genetic
27708008
RFA1_YEASTRFA1genetic
27708008
ORC2_YEASTORC2genetic
27708008
RFC5_YEASTRFC5genetic
27708008
MCM7_YEASTMCM7genetic
27708008
DPOD_YEASTPOL3genetic
27708008
NSE4_YEASTNSE4genetic
27708008
NSE3_YEASTNSE3genetic
27708008
SMT3_YEASTSMT3genetic
27708008
RSP5_YEASTRSP5genetic
27708008
ACT_YEASTACT1genetic
27708008
STT3_YEASTSTT3genetic
27708008
RNA15_YEASTRNA15genetic
27708008
DAM1_YEASTDAM1genetic
27708008
MCM10_YEASTMCM10genetic
27708008
RSC4_YEASTRSC4genetic
27708008
TAD3_YEASTTAD3genetic
27708008
RPC6_YEASTRPC34genetic
27708008
HRP1_YEASTHRP1genetic
27708008
PGTB2_YEASTBET2genetic
27708008
PCF11_YEASTPCF11genetic
27708008
GPI8_YEASTGPI8genetic
27708008
TBP_YEASTSPT15genetic
27708008
SLD3_YEASTSLD3genetic
27708008
CDC20_YEASTCDC20genetic
27708008
NUP57_YEASTNUP57genetic
27708008
ORC6_YEASTORC6genetic
27708008
ORC3_YEASTORC3genetic
27708008
BOS1_YEASTBOS1genetic
27708008
NEP1_YEASTEMG1genetic
27708008
SEC22_YEASTSEC22genetic
27708008
SEN1_YEASTSEN1genetic
27708008
ORC1_YEASTORC1genetic
27708008
RSC9_YEASTRSC9genetic
27708008
GPI12_YEASTGPI12genetic
27708008
NOP2_YEASTNOP2genetic
27708008
MVD1_YEASTMVD1genetic
27708008
CH10_YEASTHSP10genetic
27708008
TYSY_YEASTCDC21genetic
27708008
DYR_YEASTDFR1genetic
27708008
PRS10_YEASTRPT4genetic
27708008
CET1_YEASTCET1genetic
27708008
ASA1_YEASTASA1genetic
27708008
ORC4_YEASTORC4genetic
27708008
MED10_YEASTNUT2genetic
27708008
NUP60_YEASTNUP60genetic
27708008
MRC1_YEASTMRC1genetic
27708008
CSM1_YEASTCSM1genetic
27708008
OCA4_YEASTOCA4genetic
27708008
GET3_YEASTGET3genetic
27708008
RAD57_YEASTRAD57genetic
27708008
OCA6_YEASTOCA6genetic
27708008
DPB4_YEASTDPB4genetic
27708008
ARO1_YEASTARO1genetic
27708008
WDR59_YEASTMTC5genetic
27708008
NBP2_YEASTNBP2genetic
27708008
RAD9_YEASTRAD9genetic
27708008
IPK1_YEASTIPK1genetic
27708008
GET1_YEASTGET1genetic
27708008
PIB2_YEASTPIB2genetic
27708008
ITC1_YEASTITC1genetic
27708008
AROC_YEASTARO2genetic
27708008
HOS2_YEASTHOS2genetic
27708008
VAM7_YEASTVAM7genetic
27708008
RL24B_YEASTRPL24Bgenetic
27708008
OCA5_YEASTOCA5genetic
27708008
VPS29_YEASTVPS29genetic
27708008
MED20_YEASTSRB2genetic
27708008
STB5_YEASTSTB5genetic
27708008
YIA6_YEASTYIA6genetic
27708008
APN1_YEASTAPN1genetic
27708008
SET3_YEASTSET3genetic
27708008
ALAM_YEASTALT1genetic
27708008
ACE2_YEASTACE2genetic
27708008
TOP3_YEASTTOP3genetic
27708008
ARV1_YEASTARV1genetic
27708008
VIP1_YEASTVIP1genetic
27708008
SGS1_YEASTSGS1genetic
27708008
IDH1_YEASTIDH1genetic
27708008
MKS1_YEASTMKS1genetic
27708008
PHO80_YEASTPHO80genetic
27708008
ISW2_YEASTISW2genetic
27708008
RAD17_YEASTRAD17genetic
27708008
RMI1_YEASTRMI1genetic
27708008
PMA2_YEASTPMA2genetic
27708008
LGE1_YEASTLGE1genetic
27708008
DDC1_YEASTDDC1genetic
27708008
VPS10_YEASTPEP1genetic
27708008
FUI1_YEASTFUI1genetic
27708008
NU170_YEASTNUP170genetic
27708008
ETR1_YEASTETR1genetic
27708008
SWC5_YEASTSWC5genetic
27708008
YB92_YEASTYBR242Wgenetic
27708008
MTC4_YEASTMTC4genetic
27708008
GBP2_YEASTGBP2genetic
27708008
DCC1_YEASTDCC1genetic
27708008
RRT12_YEASTRRT12genetic
27708008
BUD31_YEASTBUD31genetic
27708008
ATG15_YEASTATG15genetic
27708008
PP2C1_YEASTPTC1genetic
27708008
SLX5_YEASTSLX5genetic
27708008
MBP1_YEASTMBP1genetic
27708008
BRE1_YEASTBRE1genetic
27708008
LCMT1_YEASTPPM1genetic
27708008
STP1_YEASTSTP1genetic
27708008
GET2_YEASTGET2genetic
27708008
SLX8_YEASTSLX8genetic
27708008
RAD24_YEASTRAD24genetic
27708008
ODPA_YEASTPDA1genetic
27708008
SA155_YEASTSAP155genetic
27708008
PDK2_YEASTPKP2genetic
27708008
MRM2_YEASTMRM2genetic
27708008
RTF1_YEASTRTF1genetic
27708008
TNA1_YEASTTNA1genetic
27708008
OPI1_YEASTOPI1genetic
27708008
SNF6_YEASTSNF6genetic
27708008
PPME1_YEASTPPE1genetic
27708008
WSS1_YEASTWSS1genetic
27708008
MTC6_YEASTMTC6genetic
27708008
CTF8_YEASTCTF8genetic
27708008
DAL81_YEASTDAL81genetic
27708008
IXR1_YEASTIXR1genetic
27708008
FABG_YEASTOAR1genetic
27708008
FRMSR_YEASTYKL069Wgenetic
27708008
FEN1_YEASTRAD27genetic
27708008
LST4_YEASTLST4genetic
27708008
SAC1_YEASTSAC1genetic
27708008
CSF1_YEASTCSF1genetic
27708008
SWI6_YEASTSWI6genetic
27708008
LIPB_YEASTLIP2genetic
27708008
VRP1_YEASTVRP1genetic
27708008
CDC73_YEASTCDC73genetic
27708008
CTF18_YEASTCTF18genetic
27708008
GBLP_YEASTASC1genetic
27708008
SIW14_YEASTSIW14genetic
27708008
OCA2_YEASTOCA2genetic
27708008
PHO23_YEASTPHO23genetic
27708008
PFA4_YEASTPFA4genetic
27708008
SIN3_YEASTSIN3genetic
27708008
KPR5_YEASTPRS5genetic
27708008
MSN1_YEASTMSN1genetic
27708008
GAS4_YEASTGAS4genetic
27708008
VAM10_YEASTVAM10genetic
27708008
VPS5_YEASTVPS5genetic
27708008
IDH2_YEASTIDH2genetic
27708008
LIPA_YEASTLIP5genetic
27708008
PALA_YEASTRIM20genetic
27708008
GDS1_YEASTGDS1genetic
27708008
ARL3_YEASTARL3genetic
27708008
CHMU_YEASTARO7genetic
27708008
CTF4_YEASTCTF4genetic
27708008
YP153_YEASTYPR153Wgenetic
27708008
HDA3_YEASTHDA3genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of KTHY_YEAST

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Related Literatures of Post-Translational Modification

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