WRIP1_YEAST - dbPTM
WRIP1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID WRIP1_YEAST
UniProt AC P40151
Protein Name DNA-dependent ATPase MGS1
Gene Name MGS1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 587
Subcellular Localization Nucleus .
Protein Description Involved in the maintenance of proper DNA topology and chromosome integrity via annealing of single-stranded DNA breaks. Modulates DNA polymerase delta during replication or replication-associated repair. May function as a modulator for SGS1 when DNA is damaged..
Protein Sequence MSNKRTSVEQLISCPICSRKVFFSLINSHLDICGKEKSKPSSRPQTVSSLLAGPKKRKQANSEKFIDLENKDHEIKPGLKSESDDIEIVENESKRFKAAPSTDFAKSIVEPASSRDQLHNDYESRWLQKISHLPLSEKLRPKELRDYVGQQHILSQDNGTLFKYIKQGTIPSMILWGPPGVGKTSLARLLTKTATTSSNESNVGSRYFMIETSATKANTQELRGIFEKSKKEYQLTKRRTVLFIDEIHRFNKVQQDLLLPHVENGDIILIGATTENPSFQLNNALISRCLIFVLEKLNVNELCIVLSRGIALLNKCRKQVWNIENPLKLSRSILEYVVDLSVGDTRRALNMLEMIEVSTRERKADEEELSIDDVRDIIKNNSSNGLNTYYDPKGDNHYDTISAFHKSIRGGDENASLYYLARMLQGGEDPLYVARRMIRIASEDIGLRDSSLLPLAVAAHDAVMKVGLPEADLALAQCCVALARAPKSVELYRAWKKLRAMMSENMYSLASSEIPMHIRNAPTKLMEELGYHKGYKYNPDYIEGKVQQDYFPKEVLEKCPNKTDLKFLDGKHLGDKEDPDLRQSYQG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
7Phosphorylation-MSNKRTSVEQLISC
-CCCCCCCHHHHHCC
27.9121440633
64AcetylationRKQANSEKFIDLENK
HCCCCCCCCCCCCCC
47.6524489116
332PhosphorylationNPLKLSRSILEYVVD
CHHHHCHHHHHHHHH
28.3128889911
345PhosphorylationVDLSVGDTRRALNML
HHCCHHHHHHHHHHH
19.0028889911
535PhosphorylationELGYHKGYKYNPDYI
HHCCCCCCCCCHHHH
18.3324930733

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of WRIP1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of WRIP1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of WRIP1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MAD2_YEASTMAD2physical
10688190
WRIP1_YEASTMGS1physical
10688190
SGS1_YEASTSGS1genetic
12509289
TOP3_YEASTTOP3genetic
11459965
ACT_YEASTACT1physical
16429126
RAD18_YEASTRAD18genetic
16809783
RAD5_YEASTRAD5genetic
16809783
PCNA_YEASTPOL30genetic
16809783
SIZ1_YEASTSIZ1genetic
16809783
ESC2_YEASTESC2genetic
17314980
SGS1_YEASTSGS1genetic
17314980
RAD18_YEASTRAD18genetic
17314980
VID22_YEASTVID22genetic
17314980
SPT4_YEASTSPT4genetic
17314980
RFA1_YEASTRFA1genetic
17314980
MET18_YEASTMET18genetic
17314980
TOP3_YEASTTOP3genetic
17314980
MED20_YEASTSRB2genetic
17314980
FUS3_YEASTFUS3genetic
17314980
KU80_YEASTYKU80genetic
17314980
SUS1_YEASTSUS1genetic
17314980
RAD5_YEASTRAD5genetic
11953321
DPOD_YEASTPOL3genetic
11953321
RAD18_YEASTRAD18genetic
11953321
SRS2_YEASTSRS2genetic
11953321
RAD52_YEASTRAD52genetic
11953321
UBC2_YEASTRAD6genetic
11953321
MRE11_YEASTMRE11genetic
19547744
SWD3_YEASTSWD3genetic
19547744
UBC13_YEASTUBC13genetic
21911365
POLH_YEASTRAD30genetic
21911365
REV1_YEASTREV1genetic
21911365
DPOZ_YEASTREV3genetic
21911365
PCNA_YEASTPOL30physical
21911365
RNH2C_YEASTRNH203genetic
24550002
TAF12_YEASTTAF12genetic
27708008
UAP1_YEASTQRI1genetic
27708008
NSE4_YEASTNSE4genetic
27708008
PDC2_YEASTPDC2genetic
27708008
NSE3_YEASTNSE3genetic
27708008
TFB1_YEASTTFB1genetic
27708008
SMT3_YEASTSMT3genetic
27708008
ACT_YEASTACT1genetic
27708008
CDC12_YEASTCDC12genetic
27708008
DNA2_YEASTDNA2genetic
27708008
NSE1_YEASTNSE1genetic
27708008
SMC6_YEASTSMC6genetic
27708008
NSE5_YEASTNSE5genetic
27708008
TIM23_YEASTTIM23genetic
27708008
TBF1_YEASTTBF1genetic
27708008
UBC9_HUMANUBE2Iphysical
27107014
IMA7_HUMANKPNA6physical
27107014

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of WRIP1_YEAST

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Related Literatures of Post-Translational Modification

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