THI74_YEAST - dbPTM
THI74_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID THI74_YEAST
UniProt AC Q04083
Protein Name Thiamine-repressible mitochondrial transport protein THI74
Gene Name THI74
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 370
Subcellular Localization Mitochondrion membrane
Multi-pass membrane protein .
Protein Description May be involved in thiaminediphosphate transport across the mitochondrial membrane..
Protein Sequence MNRVGIDVDHMIGVLLLAVVVVFWVGASCLTNELLETNAYNKPFFLTYLNISSFALYLTPDLWRIIQSRRKSLQERTERTLPIHTQESFSEFLPLLSSTPSTSSNLSSIADTKVKDTMRLSLLFCVLWFVANLAANAALSYTTVASSTILSSTSSFFTLFLATSLGIETFSTKKLLGLFVSLFGIILIVMQSSKQQDSVSASSFLVGNTLALLGSLGYSVYTTLLKYEISSKGLRLDIQMFLGYVGIFTFLLFWPILIILDITHMETFELPSNFHISFLVMLNCIIIFVSDYFWCKALILTSPLVVTVALTFTIPLAMFADFVWREAFFTPWYIIGVIFIFVSFFLVNHRGESAVEKDCAAVEKGPILDA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
364UbiquitinationKDCAAVEKGPILDA-
HHCCHHHCCCCCCC-
64.4923749301

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of THI74_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of THI74_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of THI74_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
REI1_YEASTREI1genetic
20093466
BRE1_YEASTBRE1genetic
20093466
RTG2_YEASTRTG2genetic
20093466
SGF73_YEASTSGF73genetic
20093466
PACC_YEASTRIM101genetic
20093466
IME1_YEASTIME1genetic
20093466
RL22A_YEASTRPL22Agenetic
20093466
SSO2_YEASTSSO2genetic
20093466
REI1_YEASTREI1genetic
27708008
BRE1_YEASTBRE1genetic
27708008
SGF73_YEASTSGF73genetic
27708008
RTG2_YEASTRTG2genetic
27708008
MED20_YEASTSRB2genetic
27708008
RL22A_YEASTRPL22Agenetic
27708008
SCS7_YEASTSCS7genetic
27708008
EOS1_YEASTEOS1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of THI74_YEAST

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Related Literatures of Post-Translational Modification

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