LCMT1_YEAST - dbPTM
LCMT1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID LCMT1_YEAST
UniProt AC Q04081
Protein Name Leucine carboxyl methyltransferase 1
Gene Name PPM1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 328
Subcellular Localization
Protein Description Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. Acts on the two major protein phosphatase 2A catalytic subunits, PPH21 and PPH22..
Protein Sequence MERIIQQTDYDALSCKLAAISVGYLPSSGLQRLSVDLSKKYTEWHRSYLITLKKFSRRAFGKVDKAMRSSFPVMNYGTYLRTVGIDAAILEFLVANEKVQVVNLGCGSDLRMLPLLQMFPHLAYVDIDYNESVELKNSILRESEILRISLGLSKEDTAKSPFLIDQGRYKLAACDLNDITETTRLLDVCTKREIPTIVISECLLCYMHNNESQLLINTIMSKFSHGLWISYDPIGGSQPNDRFGAIMQSNLKESRNLEMPTLMTYNSKEKYASRWSAAPNVIVNDMWEIFNAQIPESERKRLRSLQFLDELEELKVMQTHYILMKAQW
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of LCMT1_YEAST !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of LCMT1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of LCMT1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of LCMT1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SLT2_YEASTSLT2genetic
19269370
PP2C1_YEASTPTC1genetic
19269370
NBP2_YEASTNBP2genetic
19269370
SEM1_YEASTSEM1genetic
19269370
CUL8_YEASTRTT101genetic
19269370
MNN11_YEASTMNN11genetic
19269370
ELM1_YEASTELM1genetic
19269370
SEC22_YEASTSEC22genetic
19269370
RAD52_YEASTRAD52genetic
19269370
PTPA2_YEASTRRD2genetic
19269370
DEP1_YEASTDEP1genetic
20093466
ECM33_YEASTECM33genetic
20093466
CCZ1_YEASTCCZ1genetic
20093466
BEM1_YEASTBEM1genetic
20093466
AGP1_YEASTAGP1genetic
20093466
CSM1_YEASTCSM1genetic
20093466
VAM6_YEASTVAM6genetic
20093466
PP2C1_YEASTPTC1genetic
20093466
NHP10_YEASTNHP10genetic
20093466
MAF1_YEASTMAF1genetic
20093466
IES5_YEASTIES5genetic
20093466
IES1_YEASTIES1genetic
20093466
KAPC_YEASTTPK3genetic
20093466
MRT4_YEASTMRT4genetic
20093466
VPS13_YEASTVPS13genetic
20093466
RT109_YEASTRTT109genetic
20093466
THI73_YEASTTHI73genetic
20093466
RAD5_YEASTRAD5genetic
20093466
EMP46_YEASTEMP46genetic
20093466
MMR1_YEASTMMR1genetic
20093466
PFD6_YEASTYKE2genetic
20093466
MMS22_YEASTMMS22genetic
20093466
RL38_YEASTRPL38genetic
20093466
YL346_YEASTYLR346Cgenetic
20093466
VAC14_YEASTVAC14genetic
20093466
SST2_YEASTSST2genetic
20093466
MSC1_YEASTMSC1genetic
20093466
VPS9_YEASTVPS9genetic
20093466
YMD8_YEASTYMD8genetic
20093466
SOK2_YEASTSOK2genetic
20093466
ERG2_YEASTERG2genetic
20093466
HDA1_YEASTHDA1genetic
20093466
MED9_YEASTCSE2genetic
20093466
IRA2_YEASTIRA2genetic
20093466
BUB3_YEASTBUB3genetic
20093466
VAM10_YEASTVAM10genetic
20093466
DIA2_YEASTDIA2genetic
20093466
DDC1_YEASTDDC1genetic
20093466
TCO89_YEASTTCO89genetic
20093466
PTPA2_YEASTRRD2genetic
20093466
MED1_YEASTMED1genetic
20093466
KAR3_YEASTKAR3genetic
20093466
MMS1_YEASTMMS1genetic
20093466
MET16_YEASTMET16genetic
20093466
2ABA_YEASTCDC55genetic
11060018
RS27A_YEASTRPS27Agenetic
27708008
CCZ1_YEASTCCZ1genetic
27708008
REI1_YEASTREI1genetic
27708008
SGF29_YEASTSGF29genetic
27708008
AGP1_YEASTAGP1genetic
27708008
CSM1_YEASTCSM1genetic
27708008
NHP10_YEASTNHP10genetic
27708008
PP2C1_YEASTPTC1genetic
27708008
MAF1_YEASTMAF1genetic
27708008
IES5_YEASTIES5genetic
27708008
IES1_YEASTIES1genetic
27708008
ERJ5_YEASTERJ5genetic
27708008
PALF_YEASTRIM8genetic
27708008
SGF73_YEASTSGF73genetic
27708008
MED5_YEASTNUT1genetic
27708008
ATC1_YEASTPMR1genetic
27708008
HUR1_YEASTHUR1genetic
27708008
RTG2_YEASTRTG2genetic
27708008
OPI1_YEASTOPI1genetic
27708008
MED20_YEASTSRB2genetic
27708008
PTPA1_YEASTRRD1genetic
27708008
IMPX_YEASTIMP2genetic
27708008
THIK_YEASTPOT1genetic
27708008
ASF1_YEASTASF1genetic
27708008
PTK2_YEASTPTK2genetic
27708008
CSN12_YEASTYJR084Wgenetic
27708008
MRT4_YEASTMRT4genetic
27708008
RT109_YEASTRTT109genetic
27708008
VPS13_YEASTVPS13genetic
27708008
THI73_YEASTTHI73genetic
27708008
MMR1_YEASTMMR1genetic
27708008
PFD6_YEASTYKE2genetic
27708008
MMS22_YEASTMMS22genetic
27708008
TO6BL_YEASTREC102genetic
27708008
YL346_YEASTYLR346Cgenetic
27708008
RS3A2_YEASTRPS1Bgenetic
27708008
VPS9_YEASTVPS9genetic
27708008
NU188_YEASTNUP188genetic
27708008
SOK2_YEASTSOK2genetic
27708008
MAC1_YEASTMAC1genetic
27708008
ERG2_YEASTERG2genetic
27708008
ADE_YEASTAAH1genetic
27708008
BUB3_YEASTBUB3genetic
27708008
DIA2_YEASTDIA2genetic
27708008
PTPA2_YEASTRRD2genetic
27708008
MED1_YEASTMED1genetic
27708008
CTF4_YEASTCTF4genetic
27708008
KAR3_YEASTKAR3genetic
27708008
MET16_YEASTMET16genetic
27708008
ELP3_YEASTELP3genetic
28357221

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of LCMT1_YEAST

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Related Literatures of Post-Translational Modification

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